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P77156 (YDCU_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Inner membrane ABC transporter permease protein YdcU
Gene names
Name:ydcU
Ordered Locus Names:b1442, JW1437
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length313 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Probably part of the binding-protein-dependent transport system YdcSTUV; probably responsible for the translocation of the substrate across the membrane.

Subcellular location

Cell inner membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.

Contains 1 ABC transmembrane type-1 domain.

Ontologies

Keywords
   Biological processTransport
   Cellular componentCell inner membrane
Cell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontransporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 313313Inner membrane ABC transporter permease protein YdcU
PRO_0000060242

Regions

Topological domain1 – 2525Cytoplasmic Potential
Transmembrane26 – 4621Helical; Potential
Topological domain47 – 9246Periplasmic Potential
Transmembrane93 – 11321Helical; Potential
Topological domain114 – 1229Cytoplasmic Potential
Transmembrane123 – 14321Helical; Potential
Topological domain144 – 15411Periplasmic Potential
Transmembrane155 – 17521Helical; Potential
Topological domain176 – 18712Cytoplasmic Potential
Transmembrane188 – 20821Helical; Potential
Topological domain209 – 23022Periplasmic Potential
Transmembrane231 – 25121Helical; Potential
Topological domain2521Cytoplasmic Potential
Transmembrane253 – 27321Helical; Potential
Topological domain274 – 28310Periplasmic Potential
Transmembrane284 – 30421Helical; Potential
Topological domain305 – 3139Cytoplasmic Potential
Domain87 – 302216ABC transmembrane type-1

Sequences

Sequence LengthMass (Da)Tools
P77156 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 1B7353627183720F

FASTA31334,360
        10         20         30         40         50         60 
MAMNVLQSPS RPGLGKVSGF FWHNPGLGLF LLLLGPLMWF GIVYFGSLLT LLWQGFYTFD 

        70         80         90        100        110        120 
DFTMSVTPEL TLANIRALFN PANYDIILRT LTMAVAVTIA SAILAFPMAW YMARYTSGKM 

       130        140        150        160        170        180 
KAFFYIAVML PMWASYIVKA YAWTLLLAKD GVAQWFLQHL GLEPLLTAFL TLPAVGGNTL 

       190        200        210        220        230        240 
STSGLGRFLV FLYIWLPFMI LPVQAALERL PPSLLQASAD LGARPRQTFR YVVLPLAIPG 

       250        260        270        280        290        300 
IAAGSIFTFS LTLGDFIVPQ LVGPPGYFIG NMVYSQQGAI GNMPMAAAFT LVPIILIALY 

       310 
LAFVKRLGAF DAL

« Hide

References

[1]"A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map."
Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K. expand/collapse author list , Nakade S., Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y., Wada C., Yamamoto Y., Horiuchi T.
DNA Res. 3:363-377(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]"Global topology analysis of the Escherichia coli inner membrane proteome."
Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: K12 / MG1655 / ATCC 47076.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U00096 Genomic DNA. Translation: AAC74524.1.
AP009048 Genomic DNA. Translation: BAA15071.1.
PIRE64896.
RefSeqNP_415959.1. NC_000913.2.
YP_489707.1. NC_007779.1.

3D structure databases

ProteinModelPortalP77156.
ModBaseSearch...

Protein-protein interaction databases

STRING511145.b1442.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC74524; AAC74524; b1442.
BAA15071; BAA15071; BAA15071.
GeneID12931197.
945976.
KEGGecj:Y75_p1418.
eco:b1442.
PATRIC32118174. VBIEscCol129921_1507.

Organism-specific databases

EchoBASEEB3527.
EcoGeneEG13764. ydcU.

Phylogenomic databases

eggNOGCOG1176.
HOGENOMHOG000263581.
KOK02054.
OMAAYYMARY.
ProtClustDBCLSK864269.

Enzyme and pathway databases

BioCycEcoCyc:YDCU-MONOMER.
ECOL316407:JW1437-MONOMER.

Gene expression databases

GenevestigatorP77156.

Family and domain databases

InterProIPR000515. BPD_transp.
[Graphical view]
PfamPF00528. BPD_transp_1. 1 hit.
[Graphical view]
PROSITEPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYDCU_ECOLI
AccessionPrimary (citable) accession number: P77156
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 1, 1997
Last modified: May 1, 2013
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

SIMILARITY comments

Index of protein domains and families

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