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Protein

Inner membrane ABC transporter permease protein YdcU

Gene

ydcU

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probably part of the ABC transporter complex YdcSTUV. Probably responsible for the translocation of the substrate across the membrane.Curated

GO - Biological processi

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:YDCU-MONOMER
MetaCyc:YDCU-MONOMER

Protein family/group databases

TCDBi3.A.1.11.9 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane ABC transporter permease protein YdcUCurated
Gene namesi
Name:ydcU
Ordered Locus Names:b1442, JW1437
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13764 ydcU

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 25CytoplasmicCuratedAdd BLAST25
Transmembranei26 – 46HelicalSequence analysisAdd BLAST21
Topological domaini47 – 92PeriplasmicCuratedAdd BLAST46
Transmembranei93 – 113HelicalSequence analysisAdd BLAST21
Topological domaini114 – 122CytoplasmicCurated9
Transmembranei123 – 143HelicalSequence analysisAdd BLAST21
Topological domaini144 – 154PeriplasmicCuratedAdd BLAST11
Transmembranei155 – 175HelicalSequence analysisAdd BLAST21
Topological domaini176 – 187CytoplasmicCuratedAdd BLAST12
Transmembranei188 – 208HelicalSequence analysisAdd BLAST21
Topological domaini209 – 230PeriplasmicCuratedAdd BLAST22
Transmembranei231 – 251HelicalSequence analysisAdd BLAST21
Topological domaini252CytoplasmicCurated1
Transmembranei253 – 273HelicalSequence analysisAdd BLAST21
Topological domaini274 – 283PeriplasmicCurated10
Transmembranei284 – 304HelicalSequence analysisAdd BLAST21
Topological domaini305 – 313Cytoplasmic1 Publication9

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Inactivation of the gene does not significantly affect natural transformation.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000602421 – 313Inner membrane ABC transporter permease protein YdcUAdd BLAST313

Proteomic databases

PaxDbiP77156
PRIDEiP77156

Interactioni

Protein-protein interaction databases

BioGridi4260191, 93 interactors
STRINGi316385.ECDH10B_1572

Structurei

3D structure databases

ProteinModelPortaliP77156
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini87 – 302ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST216

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105D81 Bacteria
COG1176 LUCA
HOGENOMiHOG000263581
InParanoidiP77156
KOiK02054
OMAiYYMARYT
PhylomeDBiP77156

Family and domain databases

CDDicd06261 TM_PBP2, 1 hit
Gene3Di1.10.3720.10, 1 hit
InterProiView protein in InterPro
IPR000515 MetI-like
IPR035906 MetI-like_sf
PfamiView protein in Pfam
PF00528 BPD_transp_1, 1 hit
SUPFAMiSSF161098 SSF161098, 1 hit
PROSITEiView protein in PROSITE
PS50928 ABC_TM1, 1 hit

Sequencei

Sequence statusi: Complete.

P77156-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMNVLQSPS RPGLGKVSGF FWHNPGLGLF LLLLGPLMWF GIVYFGSLLT
60 70 80 90 100
LLWQGFYTFD DFTMSVTPEL TLANIRALFN PANYDIILRT LTMAVAVTIA
110 120 130 140 150
SAILAFPMAW YMARYTSGKM KAFFYIAVML PMWASYIVKA YAWTLLLAKD
160 170 180 190 200
GVAQWFLQHL GLEPLLTAFL TLPAVGGNTL STSGLGRFLV FLYIWLPFMI
210 220 230 240 250
LPVQAALERL PPSLLQASAD LGARPRQTFR YVVLPLAIPG IAAGSIFTFS
260 270 280 290 300
LTLGDFIVPQ LVGPPGYFIG NMVYSQQGAI GNMPMAAAFT LVPIILIALY
310
LAFVKRLGAF DAL
Length:313
Mass (Da):34,360
Last modified:February 1, 1997 - v1
Checksum:i1B7353627183720F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74524.1
AP009048 Genomic DNA Translation: BAA15071.1
PIRiE64896
RefSeqiNP_415959.1, NC_000913.3
WP_001251304.1, NZ_CP014272.1

Genome annotation databases

EnsemblBacteriaiAAC74524; AAC74524; b1442
BAA15071; BAA15071; BAA15071
GeneIDi945976
KEGGiecj:JW1437
eco:b1442
PATRICifig|1411691.4.peg.826

Similar proteinsi

Entry informationi

Entry nameiYDCU_ECOLI
AccessioniPrimary (citable) accession number: P77156
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 1, 1997
Last modified: April 25, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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