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Protein

Porin OmpL

Gene

ompL

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is unknown.1 Publication

Caution

In contrast to PubMed:11080145, PubMed:12660153 demonstrates that OmpL actually plays no perceptible role in modulating redox potential in the periplasm of E.coli.Curated

GO - Molecular functioni

  • porin activity Source: EcoCyc

GO - Biological processi

  • arabinose transmembrane transport Source: EcoliWiki
  • galactose transmembrane transport Source: EcoliWiki
  • glucose import Source: EcoliWiki
  • ion transport Source: UniProtKB-KW

Keywordsi

Molecular functionPorin
Biological processIon transport, Sugar transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:G7814-MONOMER

Protein family/group databases

TCDBi1.B.35.2.2 the oligogalacturonate-specific porin (kdgm) family

Names & Taxonomyi

Protein namesi
Recommended name:
Porin OmpL
Gene namesi
Name:ompL
Synonyms:yshA
Ordered Locus Names:b3875, JW3846
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13374 ompL

Subcellular locationi

GO - Cellular componenti

  • cell outer membrane Source: EcoliWiki
  • pore complex Source: UniProtKB-KW

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 201 PublicationAdd BLAST20
ChainiPRO_000001660521 – 230Porin OmpLAdd BLAST210

Proteomic databases

PaxDbiP76773
PRIDEiP76773

Interactioni

Protein-protein interaction databases

BioGridi4262635, 212 interactors
IntActiP76773, 21 interactors
STRINGi316385.ECDH10B_4065

Structurei

3D structure databases

ProteinModelPortaliP76773
SMRiP76773
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

eggNOGiENOG4108KUC Bacteria
ENOG410XRD5 LUCA
HOGENOMiHOG000005069
KOiK22110
OMAiETREAYN

Family and domain databases

InterProiView protein in InterPro
IPR009331 Oligogalacturonate-sp_porin
PANTHERiPTHR38105 PTHR38105, 1 hit
PfamiView protein in Pfam
PF06178 KdgM, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P76773-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKINAIILL SSLTSASVFA GAYVENREAY NLASDQGEVM LRVGYNFDMG
60 70 80 90 100
AGIMLTNTYN FQREDELKHG YNEIEGWYPL FKPTDKLTIQ PGGLINDKSI
110 120 130 140 150
GSGGAVYLDV NYKFVPWFNL TVRNRYNHNN YSSTDLSGEL DNNDTYEIGT
160 170 180 190 200
YWNFKITDKF SYTFEPHYFM RVNDFNSSNG KDHHWEITNT FRYRINEHWL
210 220 230
PYFELRWLDR NVEPYHREQN QIRIGTKYFF
Length:230
Mass (Da):27,200
Last modified:February 1, 1997 - v1
Checksum:i94743DA530F276CB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L19201 Genomic DNA Translation: AAB03009.1 Frameshift.
U00096 Genomic DNA Translation: AAC76872.1
AP009048 Genomic DNA Translation: BAE77434.1
PIRiF65192
RefSeqiNP_418311.1, NC_000913.3
WP_000723465.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76872; AAC76872; b3875
BAE77434; BAE77434; BAE77434
GeneIDi948366
KEGGiecj:JW3846
eco:b3875
PATRICifig|1411691.4.peg.2836

Similar proteinsi

Entry informationi

Entry nameiOMPL_ECOLI
AccessioniPrimary (citable) accession number: P76773
Secondary accession number(s): Q2M8H2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: April 25, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome
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Main funding by: National Institutes of Health