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P76630

- YGAZ_ECOLI

UniProt

P76630 - YGAZ_ECOLI

Protein

Inner membrane protein YgaZ

Gene

ygaZ

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. efflux transmembrane transporter activity Source: EcoCyc
    2. L-valine transmembrane transporter activity Source: EcoCyc

    GO - Biological processi

    1. L-alpha-amino acid transmembrane transport Source: GOC
    2. L-amino acid transport Source: GOC
    3. transmembrane transport Source: GOC
    4. valine transport Source: EcoCyc

    Keywords - Biological processi

    Transport

    Enzyme and pathway databases

    BioCyciEcoCyc:G7405-MONOMER.
    ECOL316407:JW2657-MONOMER.
    MetaCyc:G7405-MONOMER.

    Protein family/group databases

    TCDBi2.A.78.1.3. the branched chain amino acid exporter (liv-e) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Inner membrane protein YgaZ
    Gene namesi
    Name:ygaZ
    Ordered Locus Names:b2682, JW2657
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG13528. ygaZ.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 245245Inner membrane protein YgaZPRO_0000111781Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP76630.

    Interactioni

    Protein-protein interaction databases

    STRINGi511145.b2682.

    Structurei

    3D structure databases

    ProteinModelPortaliP76630.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 2424CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini46 – 6318PeriplasmicSequence AnalysisAdd
    BLAST
    Topological domaini85 – 10925CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini131 – 14010PeriplasmicSequence Analysis
    Topological domaini162 – 17211CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini194 – 20512PeriplasmicSequence AnalysisAdd
    BLAST
    Topological domaini227 – 24519CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei25 – 4521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei64 – 8421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei110 – 13021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei141 – 16121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei173 – 19321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei206 – 22621HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AzlC family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1296.
    HOGENOMiHOG000013807.
    OMAiFAFGMNA.
    OrthoDBiEOG6K9QNJ.
    PhylomeDBiP76630.

    Family and domain databases

    InterProiIPR011606. Brnchd-chn_aa_trnsp_permease.
    [Graphical view]
    PfamiPF03591. AzlC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P76630-1 [UniParc]FASTAAdd to Basket

    « Hide

    MESPTPQPAP GSATFMEGCK DSLPIVISYI PVAFAFGLNA TRLGFSPLES    50
    VFFSCIIYAG ASQFVITAML AAGSSLWIAA LTVMAMDVRH VLYGPSLRSR 100
    IIQRLQKSKT ALWAFGLTDE VFAAATAKLV RNNRRWSENW MIGIAFSSWS 150
    SWVFGTVIGA FSGSGLLQGY PAVEAALGFM LPALFMSFLL ASFQRKQSLC 200
    VTAALVGALA GVTLFSIPVA ILAGIVCGCL TALIQAFWQG APDEL 245
    Length:245
    Mass (Da):26,108
    Last modified:February 1, 1997 - v1
    Checksum:i22ACE8AB8D7D651B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00096 Genomic DNA. Translation: AAC75729.1.
    AP009048 Genomic DNA. Translation: BAE76784.1.
    PIRiC65048.
    RefSeqiNP_417167.1. NC_000913.3.
    YP_490896.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC75729; AAC75729; b2682.
    BAE76784; BAE76784; BAE76784.
    GeneIDi12933954.
    945093.
    KEGGiecj:Y75_p2625.
    eco:b2682.
    PATRICi32120756. VBIEscCol129921_2775.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00096 Genomic DNA. Translation: AAC75729.1 .
    AP009048 Genomic DNA. Translation: BAE76784.1 .
    PIRi C65048.
    RefSeqi NP_417167.1. NC_000913.3.
    YP_490896.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P76630.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 511145.b2682.

    Protein family/group databases

    TCDBi 2.A.78.1.3. the branched chain amino acid exporter (liv-e) family.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC75729 ; AAC75729 ; b2682 .
    BAE76784 ; BAE76784 ; BAE76784 .
    GeneIDi 12933954.
    945093.
    KEGGi ecj:Y75_p2625.
    eco:b2682.
    PATRICi 32120756. VBIEscCol129921_2775.

    Organism-specific databases

    EchoBASEi EB3299.
    EcoGenei EG13528. ygaZ.

    Phylogenomic databases

    eggNOGi COG1296.
    HOGENOMi HOG000013807.
    OMAi FAFGMNA.
    OrthoDBi EOG6K9QNJ.
    PhylomeDBi P76630.

    Enzyme and pathway databases

    BioCyci EcoCyc:G7405-MONOMER.
    ECOL316407:JW2657-MONOMER.
    MetaCyc:G7405-MONOMER.

    Miscellaneous databases

    PROi P76630.

    Gene expression databases

    Genevestigatori P76630.

    Family and domain databases

    InterProi IPR011606. Brnchd-chn_aa_trnsp_permease.
    [Graphical view ]
    Pfami PF03591. AzlC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    3. "Global topology analysis of the Escherichia coli inner membrane proteome."
      Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
      Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
      Strain: K12 / MG1655 / ATCC 47076.

    Entry informationi

    Entry nameiYGAZ_ECOLI
    AccessioniPrimary (citable) accession number: P76630
    Secondary accession number(s): Q2MAC2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1998
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 95 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3