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Protein

Inner membrane protein YgaZ

Gene

ygaZ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • efflux transmembrane transporter activity Source: EcoCyc
  • L-valine transmembrane transporter activity Source: EcoCyc

GO - Biological processi

  • valine transport Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:G7405-MONOMER.
ECOL316407:JW2657-MONOMER.
MetaCyc:G7405-MONOMER.

Protein family/group databases

TCDBi2.A.78.1.3. the branched chain amino acid exporter (liv-e) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane protein YgaZ
Gene namesi
Name:ygaZ
Ordered Locus Names:b2682, JW2657
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13528. ygaZ.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 24CytoplasmicSequence analysisAdd BLAST24
Transmembranei25 – 45HelicalSequence analysisAdd BLAST21
Topological domaini46 – 63PeriplasmicSequence analysisAdd BLAST18
Transmembranei64 – 84HelicalSequence analysisAdd BLAST21
Topological domaini85 – 109CytoplasmicSequence analysisAdd BLAST25
Transmembranei110 – 130HelicalSequence analysisAdd BLAST21
Topological domaini131 – 140PeriplasmicSequence analysis10
Transmembranei141 – 161HelicalSequence analysisAdd BLAST21
Topological domaini162 – 172CytoplasmicSequence analysisAdd BLAST11
Transmembranei173 – 193HelicalSequence analysisAdd BLAST21
Topological domaini194 – 205PeriplasmicSequence analysisAdd BLAST12
Transmembranei206 – 226HelicalSequence analysisAdd BLAST21
Topological domaini227 – 245CytoplasmicSequence analysisAdd BLAST19

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001117811 – 245Inner membrane protein YgaZAdd BLAST245

Proteomic databases

PaxDbiP76630.
PRIDEiP76630.

Interactioni

Protein-protein interaction databases

BioGridi4262948. 16 interactors.
STRINGi511145.b2682.

Structurei

3D structure databases

ProteinModelPortaliP76630.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AzlC family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108UMN. Bacteria.
COG1296. LUCA.
HOGENOMiHOG000013807.
InParanoidiP76630.
OMAiVELSFYD.
PhylomeDBiP76630.

Family and domain databases

InterProiIPR011606. Brnchd-chn_aa_trnsp_permease.
[Graphical view]
PfamiPF03591. AzlC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P76630-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESPTPQPAP GSATFMEGCK DSLPIVISYI PVAFAFGLNA TRLGFSPLES
60 70 80 90 100
VFFSCIIYAG ASQFVITAML AAGSSLWIAA LTVMAMDVRH VLYGPSLRSR
110 120 130 140 150
IIQRLQKSKT ALWAFGLTDE VFAAATAKLV RNNRRWSENW MIGIAFSSWS
160 170 180 190 200
SWVFGTVIGA FSGSGLLQGY PAVEAALGFM LPALFMSFLL ASFQRKQSLC
210 220 230 240
VTAALVGALA GVTLFSIPVA ILAGIVCGCL TALIQAFWQG APDEL
Length:245
Mass (Da):26,108
Last modified:February 1, 1997 - v1
Checksum:i22ACE8AB8D7D651B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75729.1.
AP009048 Genomic DNA. Translation: BAE76784.1.
PIRiC65048.
RefSeqiNP_417167.1. NC_000913.3.
WP_000445651.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75729; AAC75729; b2682.
BAE76784; BAE76784; BAE76784.
GeneIDi945093.
KEGGiecj:JW2657.
eco:b2682.
PATRICi32120756. VBIEscCol129921_2775.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75729.1.
AP009048 Genomic DNA. Translation: BAE76784.1.
PIRiC65048.
RefSeqiNP_417167.1. NC_000913.3.
WP_000445651.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP76630.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262948. 16 interactors.
STRINGi511145.b2682.

Protein family/group databases

TCDBi2.A.78.1.3. the branched chain amino acid exporter (liv-e) family.

Proteomic databases

PaxDbiP76630.
PRIDEiP76630.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75729; AAC75729; b2682.
BAE76784; BAE76784; BAE76784.
GeneIDi945093.
KEGGiecj:JW2657.
eco:b2682.
PATRICi32120756. VBIEscCol129921_2775.

Organism-specific databases

EchoBASEiEB3299.
EcoGeneiEG13528. ygaZ.

Phylogenomic databases

eggNOGiENOG4108UMN. Bacteria.
COG1296. LUCA.
HOGENOMiHOG000013807.
InParanoidiP76630.
OMAiVELSFYD.
PhylomeDBiP76630.

Enzyme and pathway databases

BioCyciEcoCyc:G7405-MONOMER.
ECOL316407:JW2657-MONOMER.
MetaCyc:G7405-MONOMER.

Miscellaneous databases

PROiP76630.

Family and domain databases

InterProiIPR011606. Brnchd-chn_aa_trnsp_permease.
[Graphical view]
PfamiPF03591. AzlC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYGAZ_ECOLI
AccessioniPrimary (citable) accession number: P76630
Secondary accession number(s): Q2MAC2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: November 30, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.