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P76630 (YGAZ_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Inner membrane protein YgaZ
Gene names
Name:ygaZ
Ordered Locus Names:b2682, JW2657
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length245 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Cell inner membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the AzlC family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 245245Inner membrane protein YgaZ
PRO_0000111781

Regions

Topological domain1 – 2424Cytoplasmic Potential
Transmembrane25 – 4521Helical; Potential
Topological domain46 – 6318Periplasmic Potential
Transmembrane64 – 8421Helical; Potential
Topological domain85 – 10925Cytoplasmic Potential
Transmembrane110 – 13021Helical; Potential
Topological domain131 – 14010Periplasmic Potential
Transmembrane141 – 16121Helical; Potential
Topological domain162 – 17211Cytoplasmic Potential
Transmembrane173 – 19321Helical; Potential
Topological domain194 – 20512Periplasmic Potential
Transmembrane206 – 22621Helical; Potential
Topological domain227 – 24519Cytoplasmic Potential

Sequences

Sequence LengthMass (Da)Tools
P76630 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 22ACE8AB8D7D651B

FASTA24526,108
        10         20         30         40         50         60 
MESPTPQPAP GSATFMEGCK DSLPIVISYI PVAFAFGLNA TRLGFSPLES VFFSCIIYAG 

        70         80         90        100        110        120 
ASQFVITAML AAGSSLWIAA LTVMAMDVRH VLYGPSLRSR IIQRLQKSKT ALWAFGLTDE 

       130        140        150        160        170        180 
VFAAATAKLV RNNRRWSENW MIGIAFSSWS SWVFGTVIGA FSGSGLLQGY PAVEAALGFM 

       190        200        210        220        230        240 
LPALFMSFLL ASFQRKQSLC VTAALVGALA GVTLFSIPVA ILAGIVCGCL TALIQAFWQG 


APDEL 

« Hide

References

[1]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[2]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[3]"Global topology analysis of the Escherichia coli inner membrane proteome."
Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: K12 / MG1655 / ATCC 47076.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00096 Genomic DNA. Translation: AAC75729.1.
AP009048 Genomic DNA. Translation: BAE76784.1.
PIRC65048.
RefSeqNP_417167.1. NC_000913.3.
YP_490896.1. NC_007779.1.

3D structure databases

ProteinModelPortalP76630.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING511145.b2682.

Protein family/group databases

TCDB2.A.78.1.3. the branched chain amino acid exporter (liv-e) family.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC75729; AAC75729; b2682.
BAE76784; BAE76784; BAE76784.
GeneID12933954.
945093.
KEGGecj:Y75_p2625.
eco:b2682.
PATRIC32120756. VBIEscCol129921_2775.

Organism-specific databases

EchoBASEEB3299.
EcoGeneEG13528. ygaZ.

Phylogenomic databases

eggNOGCOG1296.
HOGENOMHOG000013807.
OMAWLSWVAG.
OrthoDBEOG6K9QNJ.
PhylomeDBP76630.
ProtClustDBCLSK880458.

Enzyme and pathway databases

BioCycEcoCyc:G7405-MONOMER.
ECOL316407:JW2657-MONOMER.

Gene expression databases

GenevestigatorP76630.

Family and domain databases

InterProIPR011606. Brnchd-chn_aa_trnsp_permease.
[Graphical view]
PfamPF03591. AzlC. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP76630.

Entry information

Entry nameYGAZ_ECOLI
AccessionPrimary (citable) accession number: P76630
Secondary accession number(s): Q2MAC2
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: April 16, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene