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Protein

Putative uncharacterized transporter YgaY

Gene

ygaY

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:G7404-MONOMER.
EcoCyc:YGAY-MONOMER.
ECOL316407:JW2655-MONOMER.

Protein family/group databases

TCDBi2.A.1.36.3. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Putative uncharacterized transporter YgaY
Gene namesi
Name:ygaY
Ordered Locus Names:b2681, JW2655
ORF Names:b2680
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13527. ygaY.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei10 – 3021HelicalSequence analysisAdd
BLAST
Transmembranei50 – 7021HelicalSequence analysisAdd
BLAST
Transmembranei79 – 9921HelicalSequence analysisAdd
BLAST
Transmembranei100 – 12021HelicalSequence analysisAdd
BLAST
Transmembranei138 – 15821HelicalSequence analysisAdd
BLAST
Transmembranei166 – 18621HelicalSequence analysisAdd
BLAST
Transmembranei218 – 23821HelicalSequence analysisAdd
BLAST
Transmembranei243 – 26321HelicalSequence analysisAdd
BLAST
Transmembranei291 – 31121HelicalSequence analysisAdd
BLAST
Transmembranei337 – 35721HelicalSequence analysisAdd
BLAST
Transmembranei364 – 38421HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 394394Putative uncharacterized transporter YgaYPRO_0000173407Add
BLAST

Interactioni

Protein-protein interaction databases

BioGridi4262259. 8 interactions.
STRINGi316407.85675521.

Structurei

3D structure databases

ProteinModelPortaliP76628.
SMRiP76628. Positions 37-182, 332-359.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiP76628.
OMAiAQLGYAC.
PhylomeDBiP76628.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 2 hits.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P76628-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKPNHELSP ALIVLMSIAT GLAVASNYYA QPLLDTIARN FSLSASSAGF
60 70 80 90 100
IVTAAQLGYA AGLLFLVPLG DMFERRRLIV SMTLLAAGGM LITASSQSLA
110 120 130 140 150
MMILGTALTG LFSVVAQILV PLAATLASPD KRGKVVGTIM SGLLLGILLA
160 170 180 190 200
RTVAGLLANL GGWRTVFWVA SVLMALMALA LWRGLPQMKS ETHLNYPQLL
210 220 230 240 250
GSVFSMFISD KILRTRALLG CLTFANFSIL WTSMAFLLAA PPFNYSDGVI
260 270 280 290 300
GLFGLAGAAG ALGARPAGGF ADKGKSHHTT TFGLLLLLLS WLAIWFGHTS
310 320 330 340 350
VLALIIGILV LDLTVQGVHI TNQTVIYRIH PDARNRLTAG YMTSYFIGGA
360 370 380 390
AGSLISASAW QHGGWAGVCL AGATIALVNL LVWWRGFHRQ EAAN
Length:394
Mass (Da):41,655
Last modified:May 10, 2002 - v2
Checksum:i23EDB3DCFA79BE76
GO

Sequence cautioni

The sequence BAE76783 differs from that shown. Reason: Frameshift at position 88. Curated
The sequence U00096 differs from that shown. Reason: Frameshift at position 88. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. No translation available.
AP009048 Genomic DNA. Translation: BAE76783.1. Frameshift.
PIRiA65048.
B65048.

Genome annotation databases

EnsemblBacteriaiBAE76783; BAE76783; BAE76783.
KEGGiecj:JW2655.
PATRICi48664767. VBIEscCol107702_2708.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. No translation available.
AP009048 Genomic DNA. Translation: BAE76783.1. Frameshift.
PIRiA65048.
B65048.

3D structure databases

ProteinModelPortaliP76628.
SMRiP76628. Positions 37-182, 332-359.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262259. 8 interactions.
STRINGi316407.85675521.

Protein family/group databases

TCDBi2.A.1.36.3. the major facilitator superfamily (mfs).

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAE76783; BAE76783; BAE76783.
KEGGiecj:JW2655.
PATRICi48664767. VBIEscCol107702_2708.

Organism-specific databases

EcoGeneiEG13527. ygaY.

Phylogenomic databases

InParanoidiP76628.
OMAiAQLGYAC.
PhylomeDBiP76628.

Enzyme and pathway databases

BioCyciEcoCyc:G7404-MONOMER.
EcoCyc:YGAY-MONOMER.
ECOL316407:JW2655-MONOMER.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 2 hits.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYGAY_ECOLI
AccessioniPrimary (citable) accession number: P76628
Secondary accession number(s): P76629, Q2MAC3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2002
Last sequence update: May 10, 2002
Last modified: September 7, 2016
This is version 110 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene. There seems to be a natural frameshift that produces two separate ORFs.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.