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P76578 (YFHM_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 104. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized lipoprotein YfhM
Gene names
Name:yfhM
Ordered Locus Names:b2520, JW2504
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length1653 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existencePredicted

General annotation (Comments)

Subcellular location

Cell membrane; Lipid-anchor Potential.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1717 Potential
Chain18 – 16531636Uncharacterized lipoprotein YfhM
PRO_0000013775

Regions

Coiled coil1559 – 158931 Potential

Amino acid modifications

Lipidation181N-palmitoyl cysteine Potential
Lipidation181S-diacylglycerol cysteine Potential

Sequences

Sequence LengthMass (Da)Tools
P76578 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 13109EC5CDEB41A0

FASTA1,653181,585
        10         20         30         40         50         60 
MKKLRVAACM LMLALAGCDN NDNAPTAVKK DAPSEVTKAA SSENASSAKL SVPERQKLAQ 

        70         80         90        100        110        120 
QSAGKVLTLL DLSEVQLDGA ATLVLTFSIP LDPDQDFSRV IHVVDKKSGK VDGAWELSDN 

       130        140        150        160        170        180 
LKELRLRHLE PKRDLIVTIG KEVKALNNAT FSKDYEKTIT TRDIQPSVGF ASRGSLLPGK 

       190        200        210        220        230        240 
VVEGLPVMAL NVNNVDVNFF RVKPESLPAF ISQWEYRNSL ANWQSDKLLQ MADLVYTGRF 

       250        260        270        280        290        300 
DLNPARNTRE KLLLPLGDIK PLQQAGVYLA VMNQAGRYDY SNPATLFTLS DIGVSAHRYH 

       310        320        330        340        350        360 
NRLDIFTQSL ENGAAQQGIE VSLLNEKGQT LTQATSDAQG HVQLENDKNA ALLLARKDGQ 

       370        380        390        400        410        420 
TTLLDLKLPA LDLAEFNIAG APGYSKQFFM FGPRDLYRPG ETVILNGLLR DADGKALPNQ 

       430        440        450        460        470        480 
PIKLDVIKPD GQVLRSVVSQ PENGLYHFTW PLDSNAATGM WHIRANTGDN QYRMWDFHVE 

       490        500        510        520        530        540 
DFMPERMALN LTGEKTPLTP KDEVKFSVVG YYLYGAPANG NTLQGQLFLR PLREAVSALP 

       550        560        570        580        590        600 
GFEFGDIAAE NLSRTLDEVQ LTLDDKGRGE VSTESQWKET HSPLQVIFQG SLLESGGRPV 

       610        620        630        640        650        660 
TRRAEQAIWP ADALPGIRPQ FASKSVYDYR TDSTVKQPIV DEGSNAAFDI VYSDAQGVKK 

       670        680        690        700        710        720 
AVSGLQVRLI RERRDYYWNW SEDEGWQSQF DQKDLIENEQ TLDLKADETG KVSFPVEWGA 

       730        740        750        760        770        780 
YRLEVKAPNE AVSSVRFWAG YSWQDNSDGS GAVRPDRVTL KLDKASYRPG DTIKLHIAAP 

       790        800        810        820        830        840 
TAGKGYAMVE SSEGPLWWQE IDVRAQGLDL TIPVDKTWNR HDLYLSTLVV RPGDKSRSAT 

       850        860        870        880        890        900 
PKRAVGVLHL PLGDENRRLD LALETPAKMR PNQPLTVKIK ASTKNGEKPK QVNVLVSAVD 

       910        920        930        940        950        960 
SGVLNITDYV TPDPWQAFFG QKRYGADIYD IYGQVIEGQG RLAALRFGGD GDELKRGGKP 

       970        980        990       1000       1010       1020 
PVNHVNIVVQ QALPVTLNEQ GEGSVTLPIG DFNGELRVMA QAWTADDFGS NESKVIVAAP 

      1030       1040       1050       1060       1070       1080 
VIAELNMPRF MASGDTSRLT LDITNLTDKP QKLNVALTAS GLLELVSDSP AAVELAPGVR 

      1090       1100       1110       1120       1130       1140 
TTLFIPVRAL PGYGDGEIQA TISGLALPGE TVADQHKQWK IGVRPAFPAQ TVNYGTALQP 

      1150       1160       1170       1180       1190       1200 
GETWAIPADG LQNFSPVTLE GQLLLSGKPP LNIARYIKEL KAYPYGCLEQ TASGLFPSLY 

      1210       1220       1230       1240       1250       1260 
TNAAQLQALG IKGDSDEKRR ASVDIGISRL LQMQRDNGGF ALWDKNGDEE YWLTAYVMDF 

      1270       1280       1290       1300       1310       1320 
LVRAGEQGYS VPTDAINRGN ERLLRYLQDP GMMSIPYADN LKASKFAVQS YAALVLARQQ 

      1330       1340       1350       1360       1370       1380 
KAPLGALREI WEHRADAASG LPLLQLGVAL KTMGDATRGE EAIALALKTP RNSDERIWLG 

      1390       1400       1410       1420       1430       1440 
DYGSSLRDNA LMLSLLEENK LLPDEQYTLL NTLSQQAFGE RWLSTQESNA LFLAARTIQD 

      1450       1460       1470       1480       1490       1500 
LPGKWQAQTS FSAEQLTGEK AQNSNLNSDQ LVTLQVSNSG DQPLWLRMDA SGYPQSAPLP 

      1510       1520       1530       1540       1550       1560 
ANNVLQIERH ILGTDGKSKS LDSLRSGDLV LVWLQVKASN SVPDALVVDL LPAGLELENQ 

      1570       1580       1590       1600       1610       1620 
NLANGSASLE QSGGEVQNLL NQMQQASIKH IEFRDDRFVA AVAVDEYQPV TLVYLARAVT 

      1630       1640       1650 
PGTYQVPQPM VESMYVPQWR ATGAAEDLLI VRP 

« Hide

References

[1]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[2]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00096 Genomic DNA. Translation: AAC75573.1.
AP009048 Genomic DNA. Translation: BAE76729.1.
PIRG65028.
RefSeqNP_417015.1. NC_000913.3.
YP_490748.1. NC_007779.1.

3D structure databases

ProteinModelPortalP76578.
SMRP76578. Positions 389-521, 757-791, 856-882, 1223-1287.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-28064N.
IntActP76578. 15 interactions.
STRING511145.b2520.

Protein family/group databases

MEROPSI39.008.

Proteomic databases

PaxDbP76578.
PRIDEP76578.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC75573; AAC75573; b2520.
BAE76729; BAE76729; BAE76729.
GeneID12931809.
947302.
KEGGecj:Y75_p2473.
eco:b2520.
PATRIC32120433. VBIEscCol129921_2619.

Organism-specific databases

EchoBASEEB3175.
EcoGeneEG13394. yfhM.

Phylogenomic databases

eggNOGCOG2373.
HOGENOMHOG000275932.
KOK06894.
OMATAYAMDF.
OrthoDBEOG6X3W1C.
PhylomeDBP76578.
ProtClustDBCLSK880420.

Enzyme and pathway databases

BioCycEcoCyc:G7323-MONOMER.
ECOL316407:JW2504-MONOMER.

Gene expression databases

GenevestigatorP76578.

Family and domain databases

Gene3D1.50.10.20. 1 hit.
InterProIPR026284. A2-macglob_dom_prot_bac.
IPR002890. A2M_N.
IPR011625. A2M_N_2.
IPR021868. Alpha_2_Macroglob_MG1.
IPR001599. Macroglobln_a2.
IPR008930. Terpenoid_cyclase/PrenylTrfase.
[Graphical view]
PfamPF00207. A2M. 1 hit.
PF01835. A2M_N. 1 hit.
PF07703. A2M_N_2. 1 hit.
PF11974. MG1. 1 hit.
[Graphical view]
PIRSFPIRSF038980. A2M_bac. 1 hit.
SUPFAMSSF48239. SSF48239. 1 hit.
PROSITEPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP76578.

Entry information

Entry nameYFHM_ECOLI
AccessionPrimary (citable) accession number: P76578
Secondary accession number(s): Q2MAH7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: February 1, 1997
Last modified: April 16, 2014
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene