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Protein

Esterase YpfH

Gene

ypfH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Displays esterase activity toward palmitoyl-CoA and pNP-butyrate.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei111Charge relay systemBy similarity1
Active sitei159Charge relay systemBy similarity1
Active sitei191Charge relay systemBy similarity1

GO - Molecular functioni

  • carboxylic ester hydrolase activity Source: EcoCyc
  • hydrolase activity, acting on ester bonds Source: EcoliWiki

Keywordsi

Molecular functionHydrolase, Serine esterase

Enzyme and pathway databases

BioCyciEcoCyc:G7296-MONOMER
BRENDAi3.1.2.2 2026

Protein family/group databases

ESTHERiecoli-ypfh LYsophospholipase_carboxylesterase
MEROPSiS09.A43

Names & Taxonomyi

Protein namesi
Recommended name:
Esterase YpfH (EC:3.1.-.-)
Gene namesi
Name:ypfH
Ordered Locus Names:b2473, JW5396
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14195 ypfH

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001022761 – 232Esterase YpfHAdd BLAST232

Proteomic databases

PaxDbiP76561
PRIDEiP76561

Interactioni

Protein-protein interaction databases

BioGridi4259532, 4 interactors
IntActiP76561, 1 interactor
STRINGi316385.ECDH10B_2639

Structurei

3D structure databases

ProteinModelPortaliP76561
SMRiP76561
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4106KED Bacteria
COG0400 LUCA
HOGENOMiHOG000260141
InParanoidiP76561
KOiK06999
OMAiGHAIDDR
PhylomeDBiP76561

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR003140 PLipase/COase/thioEstase
PfamiView protein in Pfam
PF02230 Abhydrolase_2, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit

Sequencei

Sequence statusi: Complete.

P76561-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKHDHFVVQS PDKPAQQLLL LFHGVGDNPV AMGEIGNWFA PLFPDALVVS
60 70 80 90 100
VGGAEPSGNP AGRQWFSVQG ITEDNRQARV DAIMPTFIET VRYWQKQSGV
110 120 130 140 150
GANATALIGF SQGAIMVLES IKAEPGLASR VIAFNGRYAS LPETASTATT
160 170 180 190 200
IHLIHGGEDP VIDLAHAVAA QEALISAGGD VTLDIVEDLG HAIDNRSMQF
210 220 230
ALDHLRYTIP KHYFDEALSG GKPGDDDVIE MM
Length:232
Mass (Da):24,855
Last modified:May 30, 2000 - v2
Checksum:iE046F9D642076B41
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75526.2
AP009048 Genomic DNA Translation: BAE76722.1
PIRiH65022
RefSeqiNP_416968.2, NC_000913.3
WP_000679799.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75526; AAC75526; b2473
BAE76722; BAE76722; BAE76722
GeneIDi947571
KEGGiecj:JW5396
eco:b2473
PATRICifig|1411691.4.peg.4266

Similar proteinsi

Entry informationi

Entry nameiYPFH_ECOLI
AccessioniPrimary (citable) accession number: P76561
Secondary accession number(s): Q2MAI4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 30, 2000
Last modified: March 28, 2018
This is version 110 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health