P76553 (EUTG_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ethanolamine utilization protein EutG
EC=1.1.-.-

Gene names

Name:	eutG
Synonyms:	yffV
Ordered Locus Names:	b2453, JW2437

Organism

Escherichia coli (strain K12)

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	395 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	May act on the acetaldehyde produced from the degradation of ethanolamine.
Pathway	Amine and polyamine degradation; ethanolamine degradation.
Sequence similarities	Belongs to the iron-containing alcohol dehydrogenase family.

Ontologies

Keywords
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	metal ion binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
groL	P0A6F5	1	EBI-1128863,EBI-543750

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 395	395	Ethanolamine utilization protein EutG		PRO_0000087843

Sequences

	Sequence		Length	Mass (Da)
	P76553 [UniParc]. Last modified November 1, 1997. Version 2. Checksum: 13875E8CDA5B5424	FASTA	395	41,031
	10 20 30 40 50 60 MQNELQTALF QAFDTLNLQR VKTFSVPPVT LCGPGSVSSC GQQAQTRGLK HLFVMADSFL 70 80 90 100 110 120 HQAGMTAGLT RSLTVKGIAM TLWPCPVGEP CITDVCAAVA QLRESGCDGV IAFGGGSVLD 130 140 150 160 170 180 AAKAVTLLVT NPDSTLAEMS ETSVLQPRLP LIAIPTTAGT GSETTNVTVI IDAVSGRKQV 190 200 210 220 230 240 LAHASLMPDV AILDAALTEG VPSHVTAMTG IDALTHAIEA YSALNATPFT DSLAIGAIAM 250 260 270 280 290 300 IGKSLPKAVG YGHDLAARES MLLASCMAGM AFSSAGLGLC HAMAHQPGAA LHIPHGLANA 310 320 330 340 350 360 MLLPTVMEFN RMVCRERFSQ IGRALRTKKS DDRDAINAVS ELIAEVGIGK RLGDVGATSA 370 380 390 HYGAWAQAAL EDICLRSNPR TASLEQIVGL YAAAQ

References

[1]	"Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features." Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T. , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T. DNA Res. 4:91-113(1997) [PubMed: 9205837] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00096 Genomic DNA. Translation: AAC75506.2. AP009048 Genomic DNA. Translation: BAA16331.1.
PIR	D65020.
RefSeq	NP_416948.4. NC_000913.2.
3D structure databases
ProteinModelPortal	P76553.
SMR	P76553. Positions 22-394.
ModBase	Search...
Protein-protein interaction databases
IntAct	P76553. 1 interaction.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000004247; EBESCP00000004247; EBESCG00000003464. EBESCT00000017898; EBESCP00000017189; EBESCG00000016954.
GeneID	946233.
GenomeReviews	Gene locus JW2437 in contig AP009048_GR. Gene locus b2453 in contig U00096_GR.
KEGG	ecj:JW2437. eco:b2453.
PATRIC	32120289. VBIEscCol129921_2547.
Organism-specific databases
EchoBASE	EB3935.
EcoGene	EG14183. eutG.
Phylogenomic databases
eggNOG	COG1454.
GeneTree	EBGT00050000009177.
HOGENOM	HBG742415.
OMA	YSARHAT.
PhylomeDB	P76553.
ProtClustDB	PRK15454.
Enzyme and pathway databases
BioCyc	EcoCyc:G7283-MONOMER.
Gene expression databases
Genevestigator	P76553.
Family and domain databases
InterPro	IPR001670. ADH_Fe. IPR018211. ADH_Fe_CS. [Graphical view]
KO	K04022.
Pfam	PF00465. Fe-ADH. 1 hit. [Graphical view]
PROSITE	PS00913. ADH_IRON_1. 1 hit. PS00060. ADH_IRON_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EUTG_ECOLI

Accession

Primary (citable) accession number: P76553
Secondary accession number(s): P76969

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	January 25, 2012
This is version 81 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program