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Protein

Ethanolamine utilization protein EutH

Gene

eutH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Possibly involved in the transport of ethanolamine from the periplasm to the cytoplasm.

Pathwayi: ethanolamine degradation

This protein is involved in the pathway ethanolamine degradation, which is part of Amine and polyamine degradation.
View all proteins of this organism that are known to be involved in the pathway ethanolamine degradation and in Amine and polyamine degradation.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:G7282-MONOMER.
ECOL316407:JW2436-MONOMER.
UniPathwayiUPA00560.

Names & Taxonomyi

Protein namesi
Recommended name:
Ethanolamine utilization protein EutH
Alternative name(s):
Putative ethanolamine transporter
Gene namesi
Name:eutH
Synonyms:yffU
Ordered Locus Names:b2452, JW2436
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14182. eutH.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1 – 21HelicalSequence analysisAdd BLAST21
Transmembranei61 – 81HelicalSequence analysisAdd BLAST21
Transmembranei89 – 109HelicalSequence analysisAdd BLAST21
Transmembranei126 – 146HelicalSequence analysisAdd BLAST21
Transmembranei155 – 175HelicalSequence analysisAdd BLAST21
Transmembranei192 – 212HelicalSequence analysisAdd BLAST21
Transmembranei230 – 250HelicalSequence analysisAdd BLAST21
Transmembranei274 – 294HelicalSequence analysisAdd BLAST21
Transmembranei313 – 333HelicalSequence analysisAdd BLAST21
Transmembranei342 – 362HelicalSequence analysisAdd BLAST21
Transmembranei369 – 389HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000870861 – 408Ethanolamine utilization protein EutHAdd BLAST408

Proteomic databases

PaxDbiP76552.
PRIDEiP76552.

Interactioni

Protein-protein interaction databases

BioGridi4259191. 8 interactors.
DIPiDIP-9533N.
IntActiP76552. 1 interactor.
MINTiMINT-1296863.
STRINGi511145.b2452.

Structurei

3D structure databases

ProteinModelPortaliP76552.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the EutH family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105ENY. Bacteria.
COG3192. LUCA.
HOGENOMiHOG000289514.
InParanoidiP76552.
KOiK04023.
OMAiFGDHLGF.
PhylomeDBiP76552.

Family and domain databases

InterProiIPR007441. EutH.
[Graphical view]
PfamiPF04346. EutH. 1 hit.
[Graphical view]
PIRSFiPIRSF019466. EutH. 1 hit.

Sequencei

Sequence statusi: Complete.

P76552-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGINEIIMYI MMFFMLIAAV DRILSQFGGS ARFLGKFGKS IEGSGGQFEE
60 70 80 90 100
GFMAMGALGL AMVGMTALAP VLAHVLGPVI IPVYEMLGAN PSMFAGTLLA
110 120 130 140 150
CDMGGFFLAK ELAGGDVAAW LYSGLILGSM MGPTIVFSIP VALGIIEPSD
160 170 180 190 200
RRYLALGVLA GIVTIPIGCI AGGLVAMYSG VQINGQPVEF TFALILMNMI
210 220 230 240 250
PVIIVAILVA LGLKFIPEKM INGFQIFAKF LVALITLGLA AAVVKFLLGW
260 270 280 290 300
ELIPGLDPIF MAPGDKPGEV MRAIEVIGSI SCVLLGAYPM VLLLTRWFEK
310 320 330 340 350
PLMSVGKVLN MNNIAAAGMV ATLANNIPMF GMMKQMDTRG KVINCAFAVS
360 370 380 390 400
AAFALGDHLG FAAANMNAMI FPMIVGKLIG GVTAIGVAMM LVPKEDATAT

KTEAEAQS
Length:408
Mass (Da):42,807
Last modified:February 1, 1997 - v1
Checksum:i6CA68C287E00F612
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75505.1.
AP009048 Genomic DNA. Translation: BAA16330.2.
PIRiC65020.
RefSeqiNP_416947.1. NC_000913.3.
WP_000512372.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75505; AAC75505; b2452.
BAA16330; BAA16330; BAA16330.
GeneIDi944979.
KEGGiecj:JW2436.
eco:b2452.
PATRICi32120287. VBIEscCol129921_2546.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75505.1.
AP009048 Genomic DNA. Translation: BAA16330.2.
PIRiC65020.
RefSeqiNP_416947.1. NC_000913.3.
WP_000512372.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP76552.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259191. 8 interactors.
DIPiDIP-9533N.
IntActiP76552. 1 interactor.
MINTiMINT-1296863.
STRINGi511145.b2452.

Proteomic databases

PaxDbiP76552.
PRIDEiP76552.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75505; AAC75505; b2452.
BAA16330; BAA16330; BAA16330.
GeneIDi944979.
KEGGiecj:JW2436.
eco:b2452.
PATRICi32120287. VBIEscCol129921_2546.

Organism-specific databases

EchoBASEiEB3934.
EcoGeneiEG14182. eutH.

Phylogenomic databases

eggNOGiENOG4105ENY. Bacteria.
COG3192. LUCA.
HOGENOMiHOG000289514.
InParanoidiP76552.
KOiK04023.
OMAiFGDHLGF.
PhylomeDBiP76552.

Enzyme and pathway databases

UniPathwayiUPA00560.
BioCyciEcoCyc:G7282-MONOMER.
ECOL316407:JW2436-MONOMER.

Miscellaneous databases

PROiP76552.

Family and domain databases

InterProiIPR007441. EutH.
[Graphical view]
PfamiPF04346. EutH. 1 hit.
[Graphical view]
PIRSFiPIRSF019466. EutH. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiEUTH_ECOLI
AccessioniPrimary (citable) accession number: P76552
Secondary accession number(s): P76968
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.