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Protein

Uncharacterized fimbrial-like protein YfcQ

Gene

yfcQ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Part of the yfcOPQRSUV fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. Increases adhesion to eukaryotic T24 bladder epithelial cells in the absence of fim genes.1 Publication

Miscellaneous

The operon is cryptic under classical laboratory conditions, but is functional when constitutively expressed.1 Publication

GO - Biological processi

  • cell adhesion Source: EcoCyc

Enzyme and pathway databases

BioCyciEcoCyc:G7205-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized fimbrial-like protein YfcQ
Gene namesi
Name:yfcQ
Ordered Locus Names:b2334, JW2331
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14120 yfcQ

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Disruption phenotypei

Deletion of the operon under classical laboratory conditions does not result in any major effect on E.coli capacity to form biofilms compared with the wild-type strain.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_000001377219 – 162Uncharacterized fimbrial-like protein YfcQAdd BLAST144

Proteomic databases

PaxDbiP76500
PRIDEiP76500

Expressioni

Inductioni

Expression is negatively regulated by H-NS and subjected to cAMP receptor protein (CRP)-mediated catabolite repression.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4260530, 3 interactors
IntActiP76500, 12 interactors
STRINGi316385.ECDH10B_2496

Structurei

3D structure databases

ProteinModelPortaliP76500
SMRiP76500
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the fimbrial protein family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105UGQ Bacteria
ENOG4111UC7 LUCA
HOGENOMiHOG000122523
OMAiTIDVEFG

Family and domain databases

Gene3Di2.60.40.1090, 1 hit
InterProiView protein in InterPro
IPR000259 Adhesion_dom_fimbrial
IPR036937 Adhesion_dom_fimbrial_sf
IPR008966 Adhesion_dom_sf
PfamiView protein in Pfam
PF00419 Fimbrial, 1 hit
SUPFAMiSSF49401 SSF49401, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P76500-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKTFLTLLC VSSAIAHAAD EDITFHGTLL SPPTCSISGG KTIEVEFRDL
60 70 80 90 100
IIDDINGNYG RKEVPYELTC DSTTRHPDWE MTLTWTGTQT SFNDAAIETD
110 120 130 140 150
VPGFGIELQH DGQRFKLNTP LAINATDFTQ KPKLEAVPVK ASDAVLSDTN
160
FSAYATLRVD YQ
Length:162
Mass (Da):17,890
Last modified:February 1, 1997 - v1
Checksum:i2ED38E251AA3B73A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75394.1
AP009048 Genomic DNA Translation: BAE76691.1
PIRiD65006
RefSeqiNP_416837.1, NC_000913.3
WP_001232541.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75394; AAC75394; b2334
BAE76691; BAE76691; BAE76691
GeneIDi946779
KEGGiecj:JW2331
eco:b2334
PATRICifig|1411691.4.peg.4398

Similar proteinsi

Entry informationi

Entry nameiYFCQ_ECOLI
AccessioniPrimary (citable) accession number: P76500
Secondary accession number(s): Q2MAL5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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