Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized fimbrial-like protein YfcP

Gene

yfcP

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Part of the yfcOPQRSUV fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. Increases adhesion to eukaryotic T24 bladder epithelial cells in the absence of fim genes.1 Publication

Miscellaneous

The operon is cryptic under classical laboratory conditions, but is functional when constitutively expressed.1 Publication

GO - Biological processi

  • cell adhesion Source: EcoCyc

Enzyme and pathway databases

BioCyciEcoCyc:G7204-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized fimbrial-like protein YfcP
Gene namesi
Name:yfcP
Ordered Locus Names:b2333, JW2330
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14119 yfcP

Subcellular locationi

GO - Cellular componenti

  • pilus Source: UniProtKB-SubCell

Keywords - Cellular componenti

Fimbrium

Pathology & Biotechi

Disruption phenotypei

Deletion of the operon under classical laboratory conditions does not result in any major effect on E.coli capacity to form biofilms compared with the wild-type strain.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_000000925628 – 179Uncharacterized fimbrial-like protein YfcPAdd BLAST152

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi43 ↔ 83Sequence analysis

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiP76499
PRIDEiP76499

Expressioni

Inductioni

Expression is negatively regulated by H-NS and subjected to cAMP receptor protein (CRP)-mediated catabolite repression.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4259569, 11 interactors
STRINGi316385.ECDH10B_2495

Structurei

3D structure databases

ProteinModelPortaliP76499
SMRiP76499
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the fimbrial protein family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105US4 Bacteria
ENOG4111UQM LUCA
HOGENOMiHOG000260127
InParanoidiP76499
OMAiIGMETTD
PhylomeDBiP76499

Family and domain databases

Gene3Di2.60.40.1090, 1 hit
InterProiView protein in InterPro
IPR000259 Adhesion_dom_fimbrial
IPR036937 Adhesion_dom_fimbrial_sf
IPR008966 Adhesion_dom_sf
PfamiView protein in Pfam
PF00419 Fimbrial, 1 hit
SUPFAMiSSF49401 SSF49401, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P76499-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKSMIQSGG YVLLAGLILA MSSTLFAADN NLHFSGNLLS KSCALVVDGQ
60 70 80 90 100
YLAEVRFPTV SRQDLNVAGQ SARVPVVFKL KDCKGPAGYN VKVTLTGVED
110 120 130 140 150
SEQPGFLALD TSSTAQGVGI GMEKTDGMQV AINNTNGATF ALTNGNNDIN
160 170
FRAWLQAKSG RDVTIGEFTA SLTATFEYI
Length:179
Mass (Da):18,951
Last modified:February 1, 1997 - v1
Checksum:i189D4355126CEA5F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75393.1
AP009048 Genomic DNA Translation: BAE76690.1
PIRiC65006
RefSeqiNP_416836.1, NC_000913.3
WP_001043398.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75393; AAC75393; b2333
BAE76690; BAE76690; BAE76690
GeneIDi946788
KEGGiecj:JW2330
eco:b2333
PATRICifig|1411691.4.peg.4399

Similar proteinsi

Entry informationi

Entry nameiYFCP_ECOLI
AccessioniPrimary (citable) accession number: P76499
Secondary accession number(s): Q2MAL6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health