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Protein

Short-chain fatty acids transporter

Gene

atoE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Responsible for the intake of short-chain fatty acids.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:EG11671-MONOMER.
ECOL316407:JW2217-MONOMER.
MetaCyc:EG11671-MONOMER.

Protein family/group databases

TCDBi2.A.73.1.1. the short chain fatty acid uptake (atoe) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Short-chain fatty acids transporter
Gene namesi
Name:atoE
Ordered Locus Names:b2223, JW2217
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11671. atoE.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 19PeriplasmicSequence analysisAdd BLAST19
Transmembranei20 – 40HelicalSequence analysisAdd BLAST21
Topological domaini41 – 53CytoplasmicSequence analysisAdd BLAST13
Transmembranei54 – 74HelicalSequence analysisAdd BLAST21
Topological domaini75 – 102PeriplasmicSequence analysisAdd BLAST28
Transmembranei103 – 123HelicalSequence analysisAdd BLAST21
Topological domaini124 – 137CytoplasmicSequence analysisAdd BLAST14
Transmembranei138 – 158HelicalSequence analysisAdd BLAST21
Transmembranei159 – 179HelicalSequence analysisAdd BLAST21
Topological domaini180CytoplasmicSequence analysis1
Transmembranei181 – 201HelicalSequence analysisAdd BLAST21
Topological domaini202 – 244PeriplasmicSequence analysisAdd BLAST43
Transmembranei245 – 265HelicalSequence analysisAdd BLAST21
Transmembranei266 – 286HelicalSequence analysisAdd BLAST21
Topological domaini287 – 313PeriplasmicSequence analysisAdd BLAST27
Transmembranei314 – 334HelicalSequence analysisAdd BLAST21
Topological domaini335 – 351CytoplasmicSequence analysisAdd BLAST17
Transmembranei352 – 372HelicalSequence analysisAdd BLAST21
Topological domaini373 – 394PeriplasmicSequence analysisAdd BLAST22
Transmembranei395 – 415HelicalSequence analysisAdd BLAST21
Topological domaini416 – 419CytoplasmicSequence analysis4
Transmembranei420 – 440HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000647331 – 440Short-chain fatty acids transporterAdd BLAST440

Proteomic databases

PaxDbiP76460.
PRIDEiP76460.

Interactioni

Protein-protein interaction databases

BioGridi4261814. 6 interactors.
STRINGi511145.b2223.

Structurei

3D structure databases

ProteinModelPortaliP76460.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CRW. Bacteria.
COG2031. LUCA.
HOGENOMiHOG000295152.
InParanoidiP76460.
KOiK02106.
OMAiYSGFVIW.
PhylomeDBiP76460.

Family and domain databases

InterProiIPR006161. CHP00366.
IPR006160. SCFA_transpt_AtoE.
[Graphical view]
PfamiPF02667. SCFA_trans. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00366. TIGR00366. 1 hit.

Sequencei

Sequence statusi: Complete.

P76460-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIGRISRFMT RFVSRWLPDP LIFAMLLTLL TFVIALWLTP QTPISMVKMW
60 70 80 90 100
GDGFWNLLAF GMQMALIIVT GHALASSAPV KSLLRTAASA AKTPVQGVML
110 120 130 140 150
VTFFGSVACV INWGFGLVVG AMFAREVARR VPGSDYPLLI ACAYIGFLTW
160 170 180 190 200
GGGFSGSMPL LAATPGNPVE HIAGLIPVGD TLFSGFNIFI TVALIVVMPF
210 220 230 240 250
ITRMMMPKPS DVVSIDPKLL MEEADFQKQL PKDAPPSERL EESRILTLII
260 270 280 290 300
GALGIAYLAM YFSEHGFNIT INTVNLMFMI AGLLLHKTPM AYMRAISAAA
310 320 330 340 350
RSTAGILVQF PFYAGIQLMM EHSGLGGLIT EFFINVANKD TFPVMTFFSS
360 370 380 390 400
ALINFAVPSG GGHWVIQGPF VIPAAQALGA DLGKSVMAIA YGEQWMNMAQ
410 420 430 440
PFWALPALAI AGLGVRDIMG YCITALLFSG VIFVIGLTLF
Length:440
Mass (Da):47,528
Last modified:February 1, 1997 - v1
Checksum:i5C9D5ECE79F5FA71
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75283.1.
AP009048 Genomic DNA. Translation: BAA16019.1.
PIRiE64992.
RefSeqiNP_416727.1. NC_000913.3.
WP_000580275.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75283; AAC75283; b2223.
BAA16019; BAA16019; BAA16019.
GeneIDi946721.
KEGGiecj:JW2217.
eco:b2223.
PATRICi32119805. VBIEscCol129921_2312.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75283.1.
AP009048 Genomic DNA. Translation: BAA16019.1.
PIRiE64992.
RefSeqiNP_416727.1. NC_000913.3.
WP_000580275.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP76460.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261814. 6 interactors.
STRINGi511145.b2223.

Protein family/group databases

TCDBi2.A.73.1.1. the short chain fatty acid uptake (atoe) family.

Proteomic databases

PaxDbiP76460.
PRIDEiP76460.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75283; AAC75283; b2223.
BAA16019; BAA16019; BAA16019.
GeneIDi946721.
KEGGiecj:JW2217.
eco:b2223.
PATRICi32119805. VBIEscCol129921_2312.

Organism-specific databases

EchoBASEiEB1622.
EcoGeneiEG11671. atoE.

Phylogenomic databases

eggNOGiENOG4105CRW. Bacteria.
COG2031. LUCA.
HOGENOMiHOG000295152.
InParanoidiP76460.
KOiK02106.
OMAiYSGFVIW.
PhylomeDBiP76460.

Enzyme and pathway databases

BioCyciEcoCyc:EG11671-MONOMER.
ECOL316407:JW2217-MONOMER.
MetaCyc:EG11671-MONOMER.

Miscellaneous databases

PROiP76460.

Family and domain databases

InterProiIPR006161. CHP00366.
IPR006160. SCFA_transpt_AtoE.
[Graphical view]
PfamiPF02667. SCFA_trans. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00366. TIGR00366. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiATOE_ECOLI
AccessioniPrimary (citable) accession number: P76460
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.