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P76459

- ATOA_ECOLI

UniProt

P76459 - ATOA_ECOLI

Protein

Acetate CoA-transferase subunit beta

Gene

atoA

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 102 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei46 – 461PROSITE-ProRule annotation

    GO - Molecular functioni

    1. acetate CoA-transferase activity Source: EcoliWiki
    2. protein binding Source: IntAct

    GO - Biological processi

    1. short-chain fatty acid metabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Fatty acid metabolism, Lipid metabolism

    Enzyme and pathway databases

    BioCyciEcoCyc:ATOA-MONOMER.
    ECOL316407:JW2216-MONOMER.
    MetaCyc:ATOA-MONOMER.
    UniPathwayiUPA00656.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetate CoA-transferase subunit beta (EC:2.8.3.8)
    Alternative name(s):
    Acetyl-CoA:acetoacetate CoA-transferase subunit beta
    Gene namesi
    Name:atoA
    Ordered Locus Names:b2222, JW2216
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG11670. atoA.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 216216Acetate CoA-transferase subunit betaPRO_0000157915Add
    BLAST

    Proteomic databases

    PRIDEiP76459.

    Expressioni

    Gene expression databases

    GenevestigatoriP76459.

    Interactioni

    Subunit structurei

    Heterodimer.By similarity

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    bamDP0AC022EBI-1128061,EBI-1128087

    Protein-protein interaction databases

    IntActiP76459. 4 interactions.
    STRINGi511145.b2222.

    Structurei

    3D structure databases

    ProteinModelPortaliP76459.
    SMRiP76459. Positions 2-206.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG2057.
    HOGENOMiHOG000221245.
    KOiK01035.
    OMAiGMEHCAK.
    OrthoDBiEOG6HMXJG.
    PhylomeDBiP76459.

    Family and domain databases

    InterProiIPR012791. 3-oxoacid_CoA-transf_B.
    IPR004165. CoA_trans_fam_I.
    IPR004164. CoA_transf_AS.
    [Graphical view]
    PANTHERiPTHR13707. PTHR13707. 1 hit.
    PfamiPF01144. CoA_trans. 1 hit.
    [Graphical view]
    SMARTiSM00882. CoA_trans. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02428. pcaJ_scoB_fam. 1 hit.
    PROSITEiPS01274. COA_TRANSF_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P76459-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDAKQRIARR VAQELRDGDI VNLGIGLPTM VANYLPEGIH ITLQSENGFL    50
    GLGPVTTAHP DLVNAGGQPC GVLPGAAMFD SAMSFALIRG GHIDACVLGG 100
    LQVDEEANLA NWVVPGKMVP GMGGAMDLVT GSRKVIIAME HCAKDGSAKI 150
    LRRCTMPLTA QHAVHMLVTE LAVFRFIDGK MWLTEIADGC DLATVRAKTE 200
    ARFEVAADLN TQRGDL 216
    Length:216
    Mass (Da):22,960
    Last modified:February 1, 1997 - v1
    Checksum:i3F3916D024614BAE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00096 Genomic DNA. Translation: AAC75282.1.
    AP009048 Genomic DNA. Translation: BAA16018.1.
    PIRiD64992.
    RefSeqiNP_416726.1. NC_000913.3.
    YP_490463.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC75282; AAC75282; b2222.
    BAA16018; BAA16018; BAA16018.
    GeneIDi12933993.
    946719.
    KEGGiecj:Y75_p2185.
    eco:b2222.
    PATRICi32119803. VBIEscCol129921_2311.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00096 Genomic DNA. Translation: AAC75282.1 .
    AP009048 Genomic DNA. Translation: BAA16018.1 .
    PIRi D64992.
    RefSeqi NP_416726.1. NC_000913.3.
    YP_490463.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P76459.
    SMRi P76459. Positions 2-206.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P76459. 4 interactions.
    STRINGi 511145.b2222.

    Proteomic databases

    PRIDEi P76459.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC75282 ; AAC75282 ; b2222 .
    BAA16018 ; BAA16018 ; BAA16018 .
    GeneIDi 12933993.
    946719.
    KEGGi ecj:Y75_p2185.
    eco:b2222.
    PATRICi 32119803. VBIEscCol129921_2311.

    Organism-specific databases

    EchoBASEi EB1621.
    EcoGenei EG11670. atoA.

    Phylogenomic databases

    eggNOGi COG2057.
    HOGENOMi HOG000221245.
    KOi K01035.
    OMAi GMEHCAK.
    OrthoDBi EOG6HMXJG.
    PhylomeDBi P76459.

    Enzyme and pathway databases

    UniPathwayi UPA00656 .
    BioCyci EcoCyc:ATOA-MONOMER.
    ECOL316407:JW2216-MONOMER.
    MetaCyc:ATOA-MONOMER.

    Miscellaneous databases

    PROi P76459.

    Gene expression databases

    Genevestigatori P76459.

    Family and domain databases

    InterProi IPR012791. 3-oxoacid_CoA-transf_B.
    IPR004165. CoA_trans_fam_I.
    IPR004164. CoA_transf_AS.
    [Graphical view ]
    PANTHERi PTHR13707. PTHR13707. 1 hit.
    Pfami PF01144. CoA_trans. 1 hit.
    [Graphical view ]
    SMARTi SM00882. CoA_trans. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02428. pcaJ_scoB_fam. 1 hit.
    PROSITEi PS01274. COA_TRANSF_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

    Entry informationi

    Entry nameiATOA_ECOLI
    AccessioniPrimary (citable) accession number: P76459
    Secondary accession number(s): P94762
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 102 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3