SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P76458

- ATOD_ECOLI

UniProt

P76458 - ATOD_ECOLI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Acetate CoA-transferase subunit alpha
Gene
atoD, b2221, JW2215
Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

Acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.

Pathwayi

GO - Molecular functioni

  1. acetate CoA-transferase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. short-chain fatty acid metabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Fatty acid metabolism, Lipid metabolism

Enzyme and pathway databases

BioCyciEcoCyc:ATOD-MONOMER.
ECOL316407:JW2215-MONOMER.
MetaCyc:ATOD-MONOMER.
UniPathwayiUPA00656.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetate CoA-transferase subunit alpha (EC:2.8.3.8)
Alternative name(s):
Acetyl-CoA:acetoacetate-CoA transferase subunit alpha
Gene namesi
Name:atoD
Ordered Locus Names:b2221, JW2215
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG11669. atoD.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 220220Acetate CoA-transferase subunit alpha
PRO_0000157904Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP76458.

Interactioni

Subunit structurei

Heterodimer By similarity.

Protein-protein interaction databases

DIPiDIP-9191N.
IntActiP76458. 3 interactions.
MINTiMINT-1293580.
STRINGi511145.b2221.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi4 – 63
Helixi8 – 114
Helixi12 – 143
Beta strandi20 – 234
Helixi33 – 4210
Beta strandi46 – 505
Helixi62 – 665
Beta strandi70 – 778
Helixi82 – 898
Beta strandi92 – 976
Helixi100 – 11112
Beta strandi116 – 1205
Turni121 – 1244
Beta strandi133 – 1364
Beta strandi139 – 1446
Beta strandi149 – 16012
Helixi169 – 1724
Helixi175 – 1817
Beta strandi182 – 19312
Helixi200 – 2023
Helixi207 – 2093
Beta strandi212 – 2143

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1K6DX-ray1.90A/B1-220[»]
ProteinModelPortaliP76458.
SMRiP76458. Positions 1-219.

Miscellaneous databases

EvolutionaryTraceiP76458.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 307CoA-binding Reviewed prediction

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1788.
HOGENOMiHOG000221244.
KOiK01034.
OMAiNKAGRNF.
OrthoDBiEOG6HMXJG.
PhylomeDBiP76458.

Family and domain databases

InterProiIPR012792. 3-oxoacid_CoA-transf_A.
IPR004165. CoA_trans_fam_I.
IPR004163. CoA_transf_BS.
[Graphical view]
PANTHERiPTHR13707. PTHR13707. 1 hit.
PfamiPF01144. CoA_trans. 1 hit.
[Graphical view]
SMARTiSM00882. CoA_trans. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02429. pcaI_scoA_fam. 1 hit.
PROSITEiPS01273. COA_TRANSF_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P76458-1 [UniParc]FASTAAdd to Basket

« Hide

MKTKLMTLQD ATGFFRDGMT IMVGGFMGIG TPSRLVEALL ESGVRDLTLI    50
ANDTAFVDTG IGPLIVNGRV RKVIASHIGT NPETGRRMIS GEMDVVLVPQ 100
GTLIEQIRCG GAGLGGFLTP TGVGTVVEEG KQTLTLDGKT WLLERPLRAD 150
LALIRAHRCD TLGNLTYQLS ARNFNPLIAL AADITLVEPD ELVETGELQP 200
DHIVTPGAVI DHIIVSQESK 220
Length:220
Mass (Da):23,526
Last modified:February 1, 1997 - v1
Checksum:iD1DD69ECEBB2676D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00096 Genomic DNA. Translation: AAC75281.1.
AP009048 Genomic DNA. Translation: BAA16017.1.
PIRiC64992.
RefSeqiNP_416725.1. NC_000913.3.
YP_490462.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC75281; AAC75281; b2221.
BAA16017; BAA16017; BAA16017.
GeneIDi12930185.
947525.
KEGGiecj:Y75_p2184.
eco:b2221.
PATRICi32119801. VBIEscCol129921_2310.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00096 Genomic DNA. Translation: AAC75281.1 .
AP009048 Genomic DNA. Translation: BAA16017.1 .
PIRi C64992.
RefSeqi NP_416725.1. NC_000913.3.
YP_490462.1. NC_007779.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1K6D X-ray 1.90 A/B 1-220 [» ]
ProteinModelPortali P76458.
SMRi P76458. Positions 1-219.
ModBasei Search...

Protein-protein interaction databases

DIPi DIP-9191N.
IntActi P76458. 3 interactions.
MINTi MINT-1293580.
STRINGi 511145.b2221.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC75281 ; AAC75281 ; b2221 .
BAA16017 ; BAA16017 ; BAA16017 .
GeneIDi 12930185.
947525.
KEGGi ecj:Y75_p2184.
eco:b2221.
PATRICi 32119801. VBIEscCol129921_2310.

Organism-specific databases

EchoBASEi EB1620.
EcoGenei EG11669. atoD.

Phylogenomic databases

eggNOGi COG1788.
HOGENOMi HOG000221244.
KOi K01034.
OMAi NKAGRNF.
OrthoDBi EOG6HMXJG.
PhylomeDBi P76458.

Enzyme and pathway databases

UniPathwayi UPA00656 .
BioCyci EcoCyc:ATOD-MONOMER.
ECOL316407:JW2215-MONOMER.
MetaCyc:ATOD-MONOMER.

Miscellaneous databases

EvolutionaryTracei P76458.
PROi P76458.

Gene expression databases

Genevestigatori P76458.

Family and domain databases

InterProi IPR012792. 3-oxoacid_CoA-transf_A.
IPR004165. CoA_trans_fam_I.
IPR004163. CoA_transf_BS.
[Graphical view ]
PANTHERi PTHR13707. PTHR13707. 1 hit.
Pfami PF01144. CoA_trans. 1 hit.
[Graphical view ]
SMARTi SM00882. CoA_trans. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02429. pcaI_scoA_fam. 1 hit.
PROSITEi PS01273. COA_TRANSF_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiATOD_ECOLI
AccessioniPrimary (citable) accession number: P76458
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: May 14, 2014
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi