P76421 (YEGX_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein yegX

Gene names

Name:	yegX
Ordered Locus Names:	b2102, JW5345

Organism

Escherichia coli (strain K12)

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	272 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the glycosyl hydrolase 25 family.

Ontologies

Keywords
Molecular function	Glycosidase Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cell wall macromolecule catabolic process Inferred from electronic annotation. Source: InterPro peptidoglycan catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro lysozyme activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 272	272	Uncharacterized protein yegX		PRO_0000208266
Sites
	Active site	71	1	By similarity
	Active site	163	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	P76421 [UniParc]. Last modified July 11, 2001. Version 2. Checksum: 35435731C5F6C337	FASTA	272	31,604
	10 20 30 40 50 60 MQLRITSRKK LTSLLCALGL ISIVAIYPRQ TVNFFYSTAV QITDYIHFYG YRPVKSFAIR 70 80 90 100 110 120 IPASYTIHGI DVSRWQERID WQRVAKMRDN GIRLQFAFIK ATEGEKLVDP YFSRNWQLSR 130 140 150 160 170 180 ENGLLRGAYH YFSPSVSASV QARLFLQTVD FSQGDFPAVL DVEERGKLSA KELRKRVSQW 190 200 210 220 230 240 LKMVEKSTGK KPIIYSGAVF YHTNLAGYFN EYPWWVAHYY QRRPDNDGMA WRFWQHSDRG 250 260 270 QVDGINGPVD FNVFNGTVEE LQAFVDGIKE TP

References

[1]	"A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map." Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S. , Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y., Horiuchi T. DNA Res. 3:379-392(1996) [PubMed: 9097040] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00096 Genomic DNA. Translation: AAC75163.2. AP009048 Genomic DNA. Translation: BAA15970.2.
PIR	E64977.
RefSeq	NP_416605.2. NC_000913.2.
3D structure databases
ProteinModelPortal	P76421.
SMR	P76421. Positions 60-264.
ModBase	Search...
Protein family/group databases
CAZy	GH25. Glycoside Hydrolase Family 25.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000001576; EBESCP00000001576; EBESCG00000001307. EBESCT00000018136; EBESCP00000017427; EBESCG00000017191.
GeneID	945543.
GenomeReviews	Gene locus JW5345 in contig AP009048_GR. Gene locus b2102 in contig U00096_GR.
KEGG	ecj:JW5345. eco:b2102.
PATRIC	32119537. VBIEscCol129921_2179.
Organism-specific databases
EchoBASE	EB3820.
EcoGene	EG14067. yegX.
Phylogenomic databases
eggNOG	COG3757.
GeneTree	EBGT00050000011081.
HOGENOM	HBG580490.
OMA	YYFCSSA.
PhylomeDB	P76421.
ProtClustDB	CLSK880290.
Enzyme and pathway databases
BioCyc	EcoCyc:G7134-MONOMER.
Gene expression databases
Genevestigator	P76421.
Family and domain databases
InterPro	IPR002053. Glyco_hydro_25. IPR008270. Glyco_hydro_25_AS. IPR018077. Glyco_hydro_fam25_subgr. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
KO	K07273.
Pfam	PF01183. Glyco_hydro_25. 1 hit. [Graphical view]
SMART	SM00641. Glyco_25. 1 hit. [Graphical view]
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
PROSITE	PS00953. GLYCOSYL_HYDROL_F25. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YEGX_ECOLI

Accession

Primary (citable) accession number: P76421
Secondary accession number(s): O08480

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	July 11, 2001
Last modified:	January 25, 2012
This is version 85 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program