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Protein

Putative nucleoside transporter YegT

Gene

yegT

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Could be involved in nucleoside transport.By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:B2098-MONOMER.
ECOL316407:JW2085-MONOMER.

Protein family/group databases

TCDBi2.A.1.10.4. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Putative nucleoside transporter YegT
Gene namesi
Name:yegT
Ordered Locus Names:b2098, JW2085
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14063. yegT.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 88PeriplasmicSequence analysis
Transmembranei9 – 2921HelicalSequence analysisAdd
BLAST
Topological domaini30 – 389CytoplasmicSequence analysis
Transmembranei39 – 5921HelicalSequence analysisAdd
BLAST
Topological domaini60 – 634PeriplasmicSequence analysis
Transmembranei64 – 8421HelicalSequence analysisAdd
BLAST
Topological domaini85 – 906CytoplasmicSequence analysis
Transmembranei91 – 11121HelicalSequence analysisAdd
BLAST
Topological domaini112 – 13120PeriplasmicSequence analysisAdd
BLAST
Transmembranei132 – 15221HelicalSequence analysisAdd
BLAST
Topological domaini153 – 1619CytoplasmicSequence analysis
Transmembranei162 – 18221HelicalSequence analysisAdd
BLAST
Topological domaini183 – 21028PeriplasmicSequence analysisAdd
BLAST
Transmembranei211 – 23121HelicalSequence analysisAdd
BLAST
Topological domaini232 – 24413CytoplasmicSequence analysisAdd
BLAST
Transmembranei245 – 26521HelicalSequence analysisAdd
BLAST
Topological domaini266 – 28722PeriplasmicSequence analysisAdd
BLAST
Transmembranei288 – 30821HelicalSequence analysisAdd
BLAST
Topological domaini309 – 33931CytoplasmicSequence analysisAdd
BLAST
Transmembranei340 – 36021HelicalSequence analysisAdd
BLAST
Topological domaini361 – 37919PeriplasmicSequence analysisAdd
BLAST
Transmembranei380 – 40021HelicalSequence analysisAdd
BLAST
Topological domaini401 – 42525CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 425425Putative nucleoside transporter YegTPRO_0000169130Add
BLAST

Proteomic databases

PaxDbiP76417.

Interactioni

Protein-protein interaction databases

BioGridi4261530. 121 interactions.
DIPiDIP-11890N.
IntActiP76417. 1 interaction.
MINTiMINT-1263598.
STRINGi511145.b2098.

Structurei

3D structure databases

ProteinModelPortaliP76417.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EAA. Bacteria.
ENOG410ZVFU. LUCA.
HOGENOMiHOG000026502.
InParanoidiP76417.
OMAiYDFFFVS.
PhylomeDBiP76417.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR004740. Nuc_H_symport.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00889. 2A0110. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P76417-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTTAKLSFM MFVEWFIWGA WFVPLWLWLS KSGFSAGEIG WSYACTAIAA
60 70 80 90 100
ILSPILVGSI TDRFFSAQKV LAVLMFAGAL LMYFAAQQTT FAGFFPLLLA
110 120 130 140 150
YSLTYMPTIA LTNSIAFANV PDVERDFPRI RVMGTIGWIA SGLACGFLPQ
160 170 180 190 200
ILGYADISPT NIPLLITAGS SALLGVFAFF LPDTPPKSTG KMDIKVMLGL
210 220 230 240 250
DALILLRDKN FLVFFFCSFL FAMPLAFYYI FANGYLTEVG MKNATGWMTL
260 270 280 290 300
GQFSEIFFML ALPFFTKRFG IKKVLLLGLV TAAIRYGFFI YGSADEYFTY
310 320 330 340 350
ALLFLGILLH GVSYDFYYVT AYIYVDKKAP VHMRTAAQGL ITLCCQGFGS
360 370 380 390 400
LLGYRLGGVM MEKMFAYQEP VNGLTFNWSG MWTFGAVMIA IIAVLFMIFF
410 420
RESDNEITAI KVDDRDIALT QGEVK
Length:425
Mass (Da):47,359
Last modified:February 1, 1997 - v1
Checksum:i0EE5A11356A0543B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75159.1.
AP009048 Genomic DNA. Translation: BAA15967.1.
PIRiA64977.
RefSeqiNP_416601.1. NC_000913.3.
WP_000858484.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75159; AAC75159; b2098.
BAA15967; BAA15967; BAA15967.
GeneIDi946638.
KEGGiecj:JW2085.
eco:b2098.
PATRICi32119529. VBIEscCol129921_2175.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75159.1.
AP009048 Genomic DNA. Translation: BAA15967.1.
PIRiA64977.
RefSeqiNP_416601.1. NC_000913.3.
WP_000858484.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP76417.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261530. 121 interactions.
DIPiDIP-11890N.
IntActiP76417. 1 interaction.
MINTiMINT-1263598.
STRINGi511145.b2098.

Protein family/group databases

TCDBi2.A.1.10.4. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbiP76417.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75159; AAC75159; b2098.
BAA15967; BAA15967; BAA15967.
GeneIDi946638.
KEGGiecj:JW2085.
eco:b2098.
PATRICi32119529. VBIEscCol129921_2175.

Organism-specific databases

EchoBASEiEB3816.
EcoGeneiEG14063. yegT.

Phylogenomic databases

eggNOGiENOG4105EAA. Bacteria.
ENOG410ZVFU. LUCA.
HOGENOMiHOG000026502.
InParanoidiP76417.
OMAiYDFFFVS.
PhylomeDBiP76417.

Enzyme and pathway databases

BioCyciEcoCyc:B2098-MONOMER.
ECOL316407:JW2085-MONOMER.

Miscellaneous databases

PROiP76417.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR004740. Nuc_H_symport.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00889. 2A0110. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYEGT_ECOLI
AccessioniPrimary (citable) accession number: P76417
Secondary accession number(s): O08013
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: September 7, 2016
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.