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Protein

UPF0053 protein YegH

Gene

yegH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G7108-MONOMER.
ECOL316407:JW5336-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0053 protein YegH
Gene namesi
Name:yegH
Ordered Locus Names:b2063, JW5336
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14051. yegH.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei14 – 3421HelicalSequence analysisAdd
BLAST
Transmembranei51 – 7121HelicalSequence analysisAdd
BLAST
Transmembranei81 – 10121HelicalSequence analysisAdd
BLAST
Transmembranei145 – 16521HelicalSequence analysisAdd
BLAST
Transmembranei185 – 20521HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 527527UPF0053 protein YegHPRO_0000088355Add
BLAST

Proteomic databases

PaxDbiP76389.
PRIDEiP76389.

Interactioni

Protein-protein interaction databases

BioGridi4259686. 3 interactions.
DIPiDIP-11879N.
STRINGi511145.b2063.

Structurei

3D structure databases

ProteinModelPortaliP76389.
SMRiP76389. Positions 288-514.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini306 – 36661CBS 1PROSITE-ProRule annotationAdd
BLAST
Domaini371 – 42959CBS 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the UPF0053 family.Curated
Contains 2 CBS domains.PROSITE-ProRule annotation

Keywords - Domaini

CBS domain, Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EE5. Bacteria.
COG0861. LUCA.
COG1253. LUCA.
HOGENOMiHOG000279402.
InParanoidiP76389.
OMAiMVMRLLL.
PhylomeDBiP76389.

Family and domain databases

Gene3Di3.30.465.10. 1 hit.
InterProiIPR000644. CBS_dom.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR005496. Integral_membrane_TerC.
IPR005170. Transptr-assoc_dom.
[Graphical view]
PfamiPF00571. CBS. 2 hits.
PF03471. CorC_HlyC. 1 hit.
PF03741. TerC. 1 hit.
[Graphical view]
SMARTiSM00116. CBS. 2 hits.
SM01091. CorC_HlyC. 1 hit.
[Graphical view]
SUPFAMiSSF56176. SSF56176. 1 hit.
PROSITEiPS51371. CBS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P76389-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEWIADPSIW AGLITLIVIE LVLGIDNLVF IAILAEKLPP KQRDRARVTG
60 70 80 90 100
LLLAMLMRLL LLASISWLVT LTQPLFSFRS FTFSARDLIM LFGGFFLLFK
110 120 130 140 150
ATMELNERLE GKDSNNPTQR KGAKFWGVVT QIVVLDAIFS LDSVITAVGM
160 170 180 190 200
VDHLLVMMAA VVIAISLMLM ASKPLTQFVN SHPTIVILCL SFLLMIGFSL
210 220 230 240 250
VAEGFGFVIP KGYLYAAIGF SVMIEALNQL AIFNRRRFLS ANQTLRQRTT
260 270 280 290 300
EAVMRLLSGQ KEDAELDAET ASMLVDHGNQ QIFNPQERRM IERVLNLNQR
310 320 330 340 350
TVSSIMTSRH DIEHIDLNAP EEEIRQLLER NQHTRLVVTD GDDAEDLLGV
360 370 380 390 400
VHVIDLLQQS LRGEPLNLRV LIRQPLVFPE TLPLLPALEQ FRNARTHFAF
410 420 430 440 450
VVDEFGSVEG IVTLSDVTET IAGNLPNEVE EIDARHDIQK NADGSWTANG
460 470 480 490 500
HMPLEDLVQY VPLPLDEKRE YHTIAGLLME YLQRIPKPGE EVQVGDYLLK
510 520
TLQVESHRVQ KVQIIPLRKD GEMEYEV
Length:527
Mass (Da):59,450
Last modified:July 15, 1998 - v2
Checksum:i0C211895B9A0112D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75124.2.
AP009048 Genomic DNA. Translation: BAA15916.2.
PIRiF64972.
RefSeqiNP_416567.4. NC_000913.3.
WP_000454701.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75124; AAC75124; b2063.
BAA15916; BAA15916; BAA15916.
GeneIDi946566.
KEGGiecj:JW5336.
eco:b2063.
PATRICi32119459. VBIEscCol129921_2140.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75124.2.
AP009048 Genomic DNA. Translation: BAA15916.2.
PIRiF64972.
RefSeqiNP_416567.4. NC_000913.3.
WP_000454701.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP76389.
SMRiP76389. Positions 288-514.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259686. 3 interactions.
DIPiDIP-11879N.
STRINGi511145.b2063.

Proteomic databases

PaxDbiP76389.
PRIDEiP76389.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75124; AAC75124; b2063.
BAA15916; BAA15916; BAA15916.
GeneIDi946566.
KEGGiecj:JW5336.
eco:b2063.
PATRICi32119459. VBIEscCol129921_2140.

Organism-specific databases

EchoBASEiEB3804.
EcoGeneiEG14051. yegH.

Phylogenomic databases

eggNOGiENOG4105EE5. Bacteria.
COG0861. LUCA.
COG1253. LUCA.
HOGENOMiHOG000279402.
InParanoidiP76389.
OMAiMVMRLLL.
PhylomeDBiP76389.

Enzyme and pathway databases

BioCyciEcoCyc:G7108-MONOMER.
ECOL316407:JW5336-MONOMER.

Miscellaneous databases

PROiP76389.

Family and domain databases

Gene3Di3.30.465.10. 1 hit.
InterProiIPR000644. CBS_dom.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR005496. Integral_membrane_TerC.
IPR005170. Transptr-assoc_dom.
[Graphical view]
PfamiPF00571. CBS. 2 hits.
PF03471. CorC_HlyC. 1 hit.
PF03741. TerC. 1 hit.
[Graphical view]
SMARTiSM00116. CBS. 2 hits.
SM01091. CorC_HlyC. 1 hit.
[Graphical view]
SUPFAMiSSF56176. SSF56176. 1 hit.
PROSITEiPS51371. CBS. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYEGH_ECOLI
AccessioniPrimary (citable) accession number: P76389
Secondary accession number(s): P94756
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 15, 1998
Last modified: September 7, 2016
This is version 114 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.