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Protein

UPF0053 protein YegH

Gene

yegH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Enzyme and pathway databases

BioCyciEcoCyc:G7108-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0053 protein YegH
Gene namesi
Name:yegH
Ordered Locus Names:b2063, JW5336
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14051 yegH

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei14 – 34HelicalSequence analysisAdd BLAST21
Transmembranei51 – 71HelicalSequence analysisAdd BLAST21
Transmembranei81 – 101HelicalSequence analysisAdd BLAST21
Transmembranei145 – 165HelicalSequence analysisAdd BLAST21
Transmembranei185 – 205HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000883551 – 527UPF0053 protein YegHAdd BLAST527

Proteomic databases

PaxDbiP76389
PRIDEiP76389

Interactioni

Protein-protein interaction databases

BioGridi4259686, 4 interactors
DIPiDIP-11879N
STRINGi316385.ECDH10B_2213

Structurei

3D structure databases

ProteinModelPortaliP76389
SMRiP76389
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini306 – 366CBS 1PROSITE-ProRule annotationAdd BLAST61
Domaini371 – 429CBS 2PROSITE-ProRule annotationAdd BLAST59

Sequence similaritiesi

Belongs to the UPF0053 family.Curated

Keywords - Domaini

CBS domain, Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EE5 Bacteria
COG0861 LUCA
COG1253 LUCA
HOGENOMiHOG000279402
InParanoidiP76389
OMAiSDNPTQR
PhylomeDBiP76389

Family and domain databases

InterProiView protein in InterPro
IPR000644 CBS_dom
IPR036318 FAD-bd_2-like_sf
IPR005496 Integral_membrane_TerC
IPR005170 Transptr-assoc_dom
PfamiView protein in Pfam
PF00571 CBS, 2 hits
PF03471 CorC_HlyC, 1 hit
PF03741 TerC, 1 hit
SMARTiView protein in SMART
SM00116 CBS, 2 hits
SM01091 CorC_HlyC, 1 hit
SUPFAMiSSF56176 SSF56176, 1 hit
PROSITEiView protein in PROSITE
PS51371 CBS, 2 hits

Sequencei

Sequence statusi: Complete.

P76389-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEWIADPSIW AGLITLIVIE LVLGIDNLVF IAILAEKLPP KQRDRARVTG
60 70 80 90 100
LLLAMLMRLL LLASISWLVT LTQPLFSFRS FTFSARDLIM LFGGFFLLFK
110 120 130 140 150
ATMELNERLE GKDSNNPTQR KGAKFWGVVT QIVVLDAIFS LDSVITAVGM
160 170 180 190 200
VDHLLVMMAA VVIAISLMLM ASKPLTQFVN SHPTIVILCL SFLLMIGFSL
210 220 230 240 250
VAEGFGFVIP KGYLYAAIGF SVMIEALNQL AIFNRRRFLS ANQTLRQRTT
260 270 280 290 300
EAVMRLLSGQ KEDAELDAET ASMLVDHGNQ QIFNPQERRM IERVLNLNQR
310 320 330 340 350
TVSSIMTSRH DIEHIDLNAP EEEIRQLLER NQHTRLVVTD GDDAEDLLGV
360 370 380 390 400
VHVIDLLQQS LRGEPLNLRV LIRQPLVFPE TLPLLPALEQ FRNARTHFAF
410 420 430 440 450
VVDEFGSVEG IVTLSDVTET IAGNLPNEVE EIDARHDIQK NADGSWTANG
460 470 480 490 500
HMPLEDLVQY VPLPLDEKRE YHTIAGLLME YLQRIPKPGE EVQVGDYLLK
510 520
TLQVESHRVQ KVQIIPLRKD GEMEYEV
Length:527
Mass (Da):59,450
Last modified:July 15, 1998 - v2
Checksum:i0C211895B9A0112D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75124.2
AP009048 Genomic DNA Translation: BAA15916.2
PIRiF64972
RefSeqiNP_416567.4, NC_000913.3
WP_000454701.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75124; AAC75124; b2063
BAA15916; BAA15916; BAA15916
GeneIDi946566
KEGGiecj:JW5336
eco:b2063
PATRICifig|511145.12.peg.2140

Similar proteinsi

Entry informationi

Entry nameiYEGH_ECOLI
AccessioniPrimary (citable) accession number: P76389
Secondary accession number(s): P94756
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 15, 1998
Last modified: March 28, 2018
This is version 122 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health