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Protein

Uncharacterized transporter YeeO

Gene

yeeO

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • antiporter activity Source: InterPro
  • dipeptide transmembrane transporter activity Source: EcoCyc
  • drug transmembrane transporter activity Source: GO_Central
  • FAD transmembrane transporter activity Source: EcoCyc
  • FMN transmembrane transporter activity Source: EcoCyc

GO - Biological processi

  • dipeptide transmembrane transport Source: EcoCyc
  • drug transmembrane transport Source: GO_Central
  • FAD transmembrane transport Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YEEO-MONOMER.
ECOL316407:JW1965-MONOMER.

Protein family/group databases

TCDBi2.A.66.1.23. the multidrug/oligosaccharidyl-lipid/polysaccharide (mop) flippase superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized transporter YeeO
Gene namesi
Name:yeeO
Ordered Locus Names:b1985, JW1965
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13383. yeeO.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei42 – 6221HelicalSequence analysisAdd
BLAST
Transmembranei87 – 10721HelicalSequence analysisAdd
BLAST
Transmembranei122 – 14221HelicalSequence analysisAdd
BLAST
Transmembranei159 – 17921HelicalSequence analysisAdd
BLAST
Transmembranei194 – 21623HelicalSequence analysisAdd
BLAST
Transmembranei229 – 24921HelicalSequence analysisAdd
BLAST
Transmembranei266 – 28621HelicalSequence analysisAdd
BLAST
Transmembranei298 – 31821HelicalSequence analysisAdd
BLAST
Transmembranei352 – 37221HelicalSequence analysisAdd
BLAST
Transmembranei387 – 40721HelicalSequence analysisAdd
BLAST
Transmembranei434 – 45421HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 495495Uncharacterized transporter YeeOPRO_0000164253Add
BLAST

Proteomic databases

PaxDbiP76352.

Interactioni

Protein-protein interaction databases

BioGridi4259355. 153 interactions.
STRINGi511145.b1985.

Structurei

3D structure databases

ProteinModelPortaliP76352.
SMRiP76352. Positions 39-478.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105UQX. Bacteria.
COG0534. LUCA.
HOGENOMiHOG000056139.
InParanoidiP76352.
OrthoDBiEOG6FV84C.
PhylomeDBiP76352.

Family and domain databases

InterProiIPR002528. MATE_fam.
[Graphical view]
PfamiPF01554. MatE. 2 hits.
[Graphical view]
PIRSFiPIRSF006603. DinF. 1 hit.
TIGRFAMsiTIGR00797. matE. 1 hit.

Sequencei

Sequence statusi: Complete.

P76352-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWFHFLQLRS ALNISSALRQ VVHGTRWHAK RKSYKVLFWR EITPLAVPIF
60 70 80 90 100
MENACVLLMG VLSTFLVSWL GKDAMAGVGL ADSFNMVIMA FFAAIDLGTT
110 120 130 140 150
VVVAFSLGKR DRRRARVATR QSLVIMTLFA VLLATLIHHF GEQIIDFVAG
160 170 180 190 200
DATTEVKALA LTYLELTVLS YPAAAITLIG SGALRGAGNT KIPLLINGSL
210 220 230 240 250
NILNIIISGI LIYGLFSWPG LGFVGAGLGL TISRYIGAVA ILWVLAIGFN
260 270 280 290 300
PALRISLKSY FKPLNFSIIW EVMGIGIPAS VESVLFTSGR LLTQMFVAGM
310 320 330 340 350
GTSVIAGNFI AFSIAALINL PGSALGSAST IITGRRLGVG QIAQAEIQLR
360 370 380 390 400
HVFWLSTLGL TAIAWLTAPF AGVMASFYTQ DPQVKHVVVI LIWLNALFMP
410 420 430 440 450
IWSASWVLPA GFKGARDARY AMWVSMLSMW GCRVVVGYVL GIMLGWGVVG
460 470 480 490
VWMGMFADWA VRAVLFYWRM VTGRWLWKYP RPEPQKCEKK PVVSE
Length:495
Mass (Da):54,199
Last modified:November 24, 2009 - v3
Checksum:iC00C8878EB4E5994
GO

Sequence cautioni

The sequence BAA15804.2 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75048.2.
AP009048 Genomic DNA. Translation: BAA15804.2. Different initiation.
PIRiB64963.
RefSeqiNP_416491.2. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC75048; AAC75048; b1985.
BAA15804; BAA15804; BAA15804.
GeneIDi946506.
KEGGiecj:JW1965.
eco:b1985.
PATRICi32119301. VBIEscCol129921_2062.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75048.2.
AP009048 Genomic DNA. Translation: BAA15804.2. Different initiation.
PIRiB64963.
RefSeqiNP_416491.2. NC_000913.3.

3D structure databases

ProteinModelPortaliP76352.
SMRiP76352. Positions 39-478.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259355. 153 interactions.
STRINGi511145.b1985.

Protein family/group databases

TCDBi2.A.66.1.23. the multidrug/oligosaccharidyl-lipid/polysaccharide (mop) flippase superfamily.

Proteomic databases

PaxDbiP76352.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75048; AAC75048; b1985.
BAA15804; BAA15804; BAA15804.
GeneIDi946506.
KEGGiecj:JW1965.
eco:b1985.
PATRICi32119301. VBIEscCol129921_2062.

Organism-specific databases

EchoBASEiEB3164.
EcoGeneiEG13383. yeeO.

Phylogenomic databases

eggNOGiENOG4105UQX. Bacteria.
COG0534. LUCA.
HOGENOMiHOG000056139.
InParanoidiP76352.
OrthoDBiEOG6FV84C.
PhylomeDBiP76352.

Enzyme and pathway databases

BioCyciEcoCyc:YEEO-MONOMER.
ECOL316407:JW1965-MONOMER.

Miscellaneous databases

PROiP76352.

Family and domain databases

InterProiIPR002528. MATE_fam.
[Graphical view]
PfamiPF01554. MatE. 2 hits.
[Graphical view]
PIRSFiPIRSF006603. DinF. 1 hit.
TIGRFAMsiTIGR00797. matE. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYEEO_ECOLI
AccessioniPrimary (citable) accession number: P76352
Secondary accession number(s): P94752
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 24, 2009
Last modified: July 6, 2016
This is version 115 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.