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Protein

Shikimate transporter

Gene

shiA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • shikimate transmembrane transporter activity Source: EcoCyc
  • symporter activity Source: UniProtKB-KW

GO - Biological processi

  • shikimate transmembrane transport Source: EcoCyc

Keywordsi

Biological processSymport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:SHIA-MONOMER
MetaCyc:SHIA-MONOMER

Protein family/group databases

TCDBi2.A.1.6.6 the major facilitator superfamily (mfs)

Names & Taxonomyi

Protein namesi
Recommended name:
Shikimate transporter
Gene namesi
Name:shiA
Synonyms:yeeM
Ordered Locus Names:b1981, JW1962
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG20205 shiA

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 27CytoplasmicSequence analysisAdd BLAST27
Transmembranei28 – 48Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini49 – 63PeriplasmicSequence analysisAdd BLAST15
Transmembranei64 – 84Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini85 – 108CytoplasmicSequence analysisAdd BLAST24
Transmembranei109 – 129Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini130 – 132PeriplasmicSequence analysis3
Transmembranei133 – 153Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini154 – 167CytoplasmicSequence analysisAdd BLAST14
Transmembranei168 – 188Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini189 – 192PeriplasmicSequence analysis4
Transmembranei193 – 213Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini214 – 254CytoplasmicSequence analysisAdd BLAST41
Transmembranei255 – 275Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini276 – 286PeriplasmicSequence analysisAdd BLAST11
Transmembranei287 – 307Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini308 – 317CytoplasmicSequence analysis10
Transmembranei318 – 337Helical; Name=9Sequence analysisAdd BLAST20
Topological domaini338 – 340PeriplasmicSequence analysis3
Transmembranei341 – 363Helical; Name=10Sequence analysisAdd BLAST23
Topological domaini364 – 386CytoplasmicSequence analysisAdd BLAST23
Transmembranei387 – 407Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini408 – 410PeriplasmicSequence analysis3
Transmembranei411 – 431Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini432 – 438CytoplasmicSequence analysis7

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000503361 – 438Shikimate transporterAdd BLAST438

Proteomic databases

PaxDbiP76350
PRIDEiP76350

Interactioni

Protein-protein interaction databases

BioGridi4260400, 9 interactors
STRINGi316385.ECDH10B_2125

Structurei

3D structure databases

ProteinModelPortaliP76350
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CSH Bacteria
ENOG410XP7I LUCA
HOGENOMiHOG000141611
InParanoidiP76350
KOiK08172
OMAiLTVMMMG
PhylomeDBiP76350

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR004736 MHS_symport
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
PF00083 Sugar_tr, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
TIGRFAMsiTIGR00883 2A0106, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00217 SUGAR_TRANSPORT_2, 1 hit

Sequencei

Sequence statusi: Complete.

P76350-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSTLISTRP DEGTLSLSRA RRAALGSFAG AVVDWYDFLL YGITAALVFN
60 70 80 90 100
REFFPQVSPA MGTLAAFATF GVGFLFRPLG GVIFGHFGDR LGRKRMLMLT
110 120 130 140 150
VWMMGIATAL IGILPSFSTI GWWAPILLVT LRAIQGFAVG GEWGGAALLS
160 170 180 190 200
VESAPKNKKA FYSSGVQVGY GVGLLLSTGL VSLISMMTTD EQFLSWGWRI
210 220 230 240 250
PFLFSIVLVL GALWVRNGME ESAEFEQQQH YQAAAKKRIP VIEALLRHPG
260 270 280 290 300
AFLKIIALRL CELLTMYIVT AFALNYSTQN MGLPRELFLN IGLLVGGLSC
310 320 330 340 350
LTIPCFAWLA DRFGRRRVYI TGTLIGTLSA FPFFMALEAQ SIFWIVFFSI
360 370 380 390 400
MLANIAHDMV VCVQQPMFTE MFGASYRYSG AGVGYQVASV VGGGFTPFIA
410 420 430
AALITYFAGN WHSVAIYLLA GCLISAMTAL LMKDSQRA
Length:438
Mass (Da):47,817
Last modified:February 1, 1997 - v1
Checksum:iB7FFBBD5AFDAE8CC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U88529 Genomic DNA Translation: AAC46271.1
U00096 Genomic DNA Translation: AAC75045.1
AP009048 Genomic DNA Translation: BAA15801.1
PIRiG64962
RefSeqiNP_416488.1, NC_000913.3
WP_000378575.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75045; AAC75045; b1981
BAA15801; BAA15801; BAA15801
GeneIDi946495
KEGGiecj:JW1962
eco:b1981
PATRICifig|1411691.4.peg.270

Similar proteinsi

Entry informationi

Entry nameiSHIA_ECOLI
AccessioniPrimary (citable) accession number: P76350
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: April 25, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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