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Protein

Cytochrome b561 homolog 1

Gene

yodB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

heme bBy similarityNote: Binds 2 heme B (iron-protoporphyrin IX) groups per molecule.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi12 – 121Iron (heme axial ligand)Sequence analysis
Metal bindingi46 – 461Iron (heme axial ligand)Sequence analysis
Metal bindingi152 – 1521Iron (heme axial ligand)Sequence analysis
Metal bindingi159 – 1591Iron (heme axial ligand)Sequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7062-MONOMER.
ECOL316407:JW5323-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome b561 homolog 1
Gene namesi
Name:yodB
Ordered Locus Names:b1974, JW5323
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14050. yodB.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 77PeriplasmicSequence analysis
Transmembranei8 – 2821HelicalSequence analysisAdd
BLAST
Topological domaini29 – 8557CytoplasmicSequence analysisAdd
BLAST
Transmembranei86 – 10621HelicalSequence analysisAdd
BLAST
Topological domaini107 – 14135PeriplasmicSequence analysisAdd
BLAST
Transmembranei142 – 16221HelicalSequence analysisAdd
BLAST
Topological domaini163 – 17614CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 176176Cytochrome b561 homolog 1PRO_0000199974Add
BLAST

Proteomic databases

PaxDbiP76345.

Interactioni

Protein-protein interaction databases

BioGridi4260395. 6 interactions.
STRINGi511145.b1974.

Structurei

3D structure databases

ProteinModelPortaliP76345.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome b561 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108VKM. Bacteria.
COG3038. LUCA.
HOGENOMiHOG000110384.
InParanoidiP76345.
OMAiSVERNLM.
OrthoDBiEOG65F8V2.
PhylomeDBiP76345.

Family and domain databases

InterProiIPR011577. Cyt_b561_bac/Ni-Hgenase.
IPR016174. Di-haem_cyt_TM.
[Graphical view]
PfamiPF01292. Ni_hydr_CYTB. 1 hit.
[Graphical view]
SUPFAMiSSF81342. SSF81342. 1 hit.

Sequencei

Sequence statusi: Complete.

P76345-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRFSKTQIY LHWITLLFVA ITYAAMELRG WFPKGSSTYL LMRETHYNAG
60 70 80 90 100
IFVWVLMFSR LIIKHRYSDP SIVPPPPAWQ MKAASLMHIM LYITFLALPL
110 120 130 140 150
LGIALMAYSG KSWSFLGFNV SPFVTPNSEI KALIKNIHET WANIGYFLIA
160 170
AHAGAALFHH YIQKDNTLLR MMPRRK
Length:176
Mass (Da):20,337
Last modified:November 1, 1997 - v2
Checksum:iD992943D0C3A950A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75040.2.
AP009048 Genomic DNA. Translation: BAA15798.2.
PIRiB64962.
RefSeqiNP_416483.4. NC_000913.3.
WP_001079074.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75040; AAC75040; b1974.
BAA15798; BAA15798; BAA15798.
GeneIDi946491.
KEGGiecj:JW5323.
eco:b1974.
PATRICi32119279. VBIEscCol129921_2054.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75040.2.
AP009048 Genomic DNA. Translation: BAA15798.2.
PIRiB64962.
RefSeqiNP_416483.4. NC_000913.3.
WP_001079074.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP76345.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260395. 6 interactions.
STRINGi511145.b1974.

Proteomic databases

PaxDbiP76345.

Protocols and materials databases

DNASUi946491.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75040; AAC75040; b1974.
BAA15798; BAA15798; BAA15798.
GeneIDi946491.
KEGGiecj:JW5323.
eco:b1974.
PATRICi32119279. VBIEscCol129921_2054.

Organism-specific databases

EchoBASEiEB3803.
EcoGeneiEG14050. yodB.

Phylogenomic databases

eggNOGiENOG4108VKM. Bacteria.
COG3038. LUCA.
HOGENOMiHOG000110384.
InParanoidiP76345.
OMAiSVERNLM.
OrthoDBiEOG65F8V2.
PhylomeDBiP76345.

Enzyme and pathway databases

BioCyciEcoCyc:G7062-MONOMER.
ECOL316407:JW5323-MONOMER.

Miscellaneous databases

PROiP76345.

Family and domain databases

InterProiIPR011577. Cyt_b561_bac/Ni-Hgenase.
IPR016174. Di-haem_cyt_TM.
[Graphical view]
PfamiPF01292. Ni_hydr_CYTB. 1 hit.
[Graphical view]
SUPFAMiSSF81342. SSF81342. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiC56H_ECOLI
AccessioniPrimary (citable) accession number: P76345
Secondary accession number(s): P94749
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 11, 2016
This is version 112 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.