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P76340

- YEDW_ECOLI

UniProt

P76340 - YEDW_ECOLI

Protein

Probable transcriptional regulatory protein YedW

Gene

yedW

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 114 (01 Oct 2014)
      Sequence version 2 (27 Apr 2001)
      Previous versions | rss
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    Functioni

    Probable member of a two-component regulatory system YedW/YedV.

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. phosphorelay response regulator activity Source: InterPro

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation, Two-component regulatory system

    Keywords - Ligandi

    DNA-binding

    Enzyme and pathway databases

    BioCyciEcoCyc:G7057-MONOMER.
    ECOL316407:JW5322-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable transcriptional regulatory protein YedW
    Gene namesi
    Name:yedW
    Ordered Locus Names:b1969, JW5322
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG14045. yedW.

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 223223Probable transcriptional regulatory protein YedWPRO_0000081360Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei51 – 5114-aspartylphosphatePROSITE-ProRule annotation

    Post-translational modificationi

    Phosphorylated by YedV.1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PaxDbiP76340.
    PRIDEiP76340.

    Expressioni

    Gene expression databases

    GenevestigatoriP76340.

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-11853N.
    IntActiP76340. 2 interactions.
    MINTiMINT-1223015.
    STRINGi511145.b1969.

    Structurei

    3D structure databases

    ProteinModelPortaliP76340.
    SMRiP76340. Positions 2-216.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 115115Response regulatoryPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 response regulatory domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0745.
    HOGENOMiHOG000034815.
    KOiK02483.
    OMAiMTYDLWH.
    OrthoDBiEOG6G4VQG.
    PhylomeDBiP76340.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    InterProiIPR011006. CheY-like_superfamily.
    IPR001867. Sig_transdc_resp-reg_C.
    IPR016032. Sig_transdc_resp-reg_C-effctor.
    IPR006291. Sig_transdc_resp-reg_metal.
    IPR001789. Sig_transdc_resp-reg_receiver.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF00072. Response_reg. 1 hit.
    PF00486. Trans_reg_C. 1 hit.
    [Graphical view]
    SMARTiSM00448. REC. 1 hit.
    SM00862. Trans_reg_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF46894. SSF46894. 1 hit.
    SSF52172. SSF52172. 1 hit.
    TIGRFAMsiTIGR01387. cztR_silR_copR. 1 hit.
    PROSITEiPS50110. RESPONSE_REGULATORY. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P76340-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKILLIEDNQ RTQEWVTQGL SEAGYVIDAV SDGRDGLYLA LKDDYALIIL    50
    DIMLPGMDGW QILQTLRTAK QTPVICLTAR DSVDDRVRGL DSGANDYLVK 100
    PFSFSELLAR VRAQLRQHHA LNSTLEISGL RMDSVSHSVS RDNISITLTR 150
    KEFQLLWLLA SRAGEIIPRT VIASEIWGIN FDSDTNTVDV AIRRLRAKVD 200
    DPFPEKLIAT IRGMGYSFVA VKK 223
    Length:223
    Mass (Da):25,018
    Last modified:April 27, 2001 - v2
    Checksum:i4A595D7430C2E2B5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00096 Genomic DNA. Translation: AAC75035.2.
    AP009048 Genomic DNA. Translation: BAA15796.2.
    PIRiE64961.
    RefSeqiNP_416478.2. NC_000913.3.
    YP_490219.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC75035; AAC75035; b1969.
    BAA15796; BAA15796; BAA15796.
    GeneIDi12931392.
    946486.
    KEGGiecj:Y75_p1936.
    eco:b1969.
    PATRICi32119269. VBIEscCol129921_2049.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00096 Genomic DNA. Translation: AAC75035.2 .
    AP009048 Genomic DNA. Translation: BAA15796.2 .
    PIRi E64961.
    RefSeqi NP_416478.2. NC_000913.3.
    YP_490219.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P76340.
    SMRi P76340. Positions 2-216.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-11853N.
    IntActi P76340. 2 interactions.
    MINTi MINT-1223015.
    STRINGi 511145.b1969.

    Proteomic databases

    PaxDbi P76340.
    PRIDEi P76340.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC75035 ; AAC75035 ; b1969 .
    BAA15796 ; BAA15796 ; BAA15796 .
    GeneIDi 12931392.
    946486.
    KEGGi ecj:Y75_p1936.
    eco:b1969.
    PATRICi 32119269. VBIEscCol129921_2049.

    Organism-specific databases

    EchoBASEi EB3798.
    EcoGenei EG14045. yedW.

    Phylogenomic databases

    eggNOGi COG0745.
    HOGENOMi HOG000034815.
    KOi K02483.
    OMAi MTYDLWH.
    OrthoDBi EOG6G4VQG.
    PhylomeDBi P76340.

    Enzyme and pathway databases

    BioCyci EcoCyc:G7057-MONOMER.
    ECOL316407:JW5322-MONOMER.

    Miscellaneous databases

    PROi P76340.

    Gene expression databases

    Genevestigatori P76340.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    InterProi IPR011006. CheY-like_superfamily.
    IPR001867. Sig_transdc_resp-reg_C.
    IPR016032. Sig_transdc_resp-reg_C-effctor.
    IPR006291. Sig_transdc_resp-reg_metal.
    IPR001789. Sig_transdc_resp-reg_receiver.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF00072. Response_reg. 1 hit.
    PF00486. Trans_reg_C. 1 hit.
    [Graphical view ]
    SMARTi SM00448. REC. 1 hit.
    SM00862. Trans_reg_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46894. SSF46894. 1 hit.
    SSF52172. SSF52172. 1 hit.
    TIGRFAMsi TIGR01387. cztR_silR_copR. 1 hit.
    PROSITEi PS50110. RESPONSE_REGULATORY. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    4. "Functional characterization in vitro of all two-component signal transduction systems from Escherichia coli."
      Yamamoto K., Hirao K., Oshima T., Aiba H., Utsumi R., Ishihama A.
      J. Biol. Chem. 280:1448-1456(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION.
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

    Entry informationi

    Entry nameiYEDW_ECOLI
    AccessioniPrimary (citable) accession number: P76340
    Secondary accession number(s): P97172
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: April 27, 2001
    Last modified: October 1, 2014
    This is version 114 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3