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P76340 (YEDW_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 112. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable transcriptional regulatory protein YedW
Gene names
Name:yedW
Ordered Locus Names:b1969, JW5322
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length223 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Probable member of a two-component regulatory system YedW/YedV.

Subcellular location

Cytoplasm Probable.

Post-translational modification

Phosphorylated by YedV. Ref.4

Sequence similarities

Contains 1 response regulatory domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 223223Probable transcriptional regulatory protein YedW
PRO_0000081360

Regions

Domain1 – 115115Response regulatory

Amino acid modifications

Modified residue5114-aspartylphosphate By similarity

Sequences

Sequence LengthMass (Da)Tools
P76340 [UniParc].

Last modified April 27, 2001. Version 2.
Checksum: 4A595D7430C2E2B5

FASTA22325,018
        10         20         30         40         50         60 
MKILLIEDNQ RTQEWVTQGL SEAGYVIDAV SDGRDGLYLA LKDDYALIIL DIMLPGMDGW 

        70         80         90        100        110        120 
QILQTLRTAK QTPVICLTAR DSVDDRVRGL DSGANDYLVK PFSFSELLAR VRAQLRQHHA 

       130        140        150        160        170        180 
LNSTLEISGL RMDSVSHSVS RDNISITLTR KEFQLLWLLA SRAGEIIPRT VIASEIWGIN 

       190        200        210        220 
FDSDTNTVDV AIRRLRAKVD DPFPEKLIAT IRGMGYSFVA VKK 

« Hide

References

« Hide 'large scale' references
[1]"A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map."
Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S. expand/collapse author list , Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y., Horiuchi T.
DNA Res. 3:379-392(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]"Functional characterization in vitro of all two-component signal transduction systems from Escherichia coli."
Yamamoto K., Hirao K., Oshima T., Aiba H., Utsumi R., Ishihama A.
J. Biol. Chem. 280:1448-1456(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION.
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00096 Genomic DNA. Translation: AAC75035.2.
AP009048 Genomic DNA. Translation: BAA15796.2.
PIRE64961.
RefSeqNP_416478.2. NC_000913.3.
YP_490219.1. NC_007779.1.

3D structure databases

ProteinModelPortalP76340.
SMRP76340. Positions 2-216.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-11853N.
IntActP76340. 2 interactions.
MINTMINT-1223015.
STRING511145.b1969.

Proteomic databases

PaxDbP76340.
PRIDEP76340.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC75035; AAC75035; b1969.
BAA15796; BAA15796; BAA15796.
GeneID12931392.
946486.
KEGGecj:Y75_p1936.
eco:b1969.
PATRIC32119269. VBIEscCol129921_2049.

Organism-specific databases

EchoBASEEB3798.
EcoGeneEG14045. yedW.

Phylogenomic databases

eggNOGCOG0745.
HOGENOMHOG000034815.
KOK02483.
OMAYVLREPH.
OrthoDBEOG6G4VQG.
PhylomeDBP76340.
ProtClustDBPRK11517.

Enzyme and pathway databases

BioCycEcoCyc:G7057-MONOMER.
ECOL316407:JW5322-MONOMER.

Gene expression databases

GenevestigatorP76340.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
InterProIPR011006. CheY-like_superfamily.
IPR001867. Sig_transdc_resp-reg_C.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR006291. Sig_transdc_resp-reg_metal.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF00072. Response_reg. 1 hit.
PF00486. Trans_reg_C. 1 hit.
[Graphical view]
SMARTSM00448. REC. 1 hit.
SM00862. Trans_reg_C. 1 hit.
[Graphical view]
SUPFAMSSF46894. SSF46894. 1 hit.
SSF52172. SSF52172. 1 hit.
TIGRFAMsTIGR01387. cztR_silR_copR. 1 hit.
PROSITEPS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP76340.

Entry information

Entry nameYEDW_ECOLI
AccessionPrimary (citable) accession number: P76340
Secondary accession number(s): P97172
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: April 27, 2001
Last modified: April 16, 2014
This is version 112 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene