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P76269 (YEBQ_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Uncharacterized transporter YebQ
Gene names
Name:yebQ
Ordered Locus Names:b1828, JW5299
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length457 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Subcellular location

Cell inner membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the major facilitator superfamily. TCR/tet family.

Ontologies

Keywords
   Biological processTransport
   Cellular componentCell inner membrane
Cell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtransmembrane transport

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 457457Uncharacterized transporter YebQ
PRO_0000173449

Regions

Transmembrane15 – 3521Helical; Potential
Transmembrane54 – 7421Helical; Potential
Transmembrane87 – 10721Helical; Potential
Transmembrane112 – 13221Helical; Potential
Transmembrane144 – 16421Helical; Potential
Transmembrane166 – 18621Helical; Potential
Transmembrane205 – 22521Helical; Potential
Transmembrane229 – 24921Helical; Potential
Transmembrane269 – 28921Helical; Potential
Transmembrane308 – 32821Helical; Potential
Transmembrane334 – 35421Helical; Potential
Transmembrane357 – 37721Helical; Potential
Transmembrane400 – 42021Helical; Potential
Transmembrane428 – 44821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P76269 [UniParc].

Last modified April 27, 2001. Version 2.
Checksum: A973850A469E7B1F

FASTA45748,152
        10         20         30         40         50         60 
MPKVQADGLP LPQRYGAILT IVIGISMAVL DGAIANVALP TIATDLHATP ASSIWVVNAY 

        70         80         90        100        110        120 
QIAIVISLLS FSFLGDMFGY RRIYKCGLVV FLLSSLFCAL SDSLQMLTLA RVIQGFGGAA 

       130        140        150        160        170        180 
LMSVNTALIR LIYPQRFLGR GMGINSFIVA VSSAAGPTIA AAILSIASWK WLFLINVPLG 

       190        200        210        220        230        240 
IIALLLAMRF LPPNGSRASK PRFDLPSAVM NALTFGLLIT ALSGFAQGQS LTLIAAELVV 

       250        260        270        280        290        300 
MVVVGIFFIR RQLSLPVPLL PVDLLRIPLF SLSICTSVCS FCAQMLAMVS LPFYLQTVLG 

       310        320        330        340        350        360 
RSEVETGLLL TPWPLATMVM APLAGYLIER VHAGLLGALG LFIMAAGLFS LVLLPASPAD 

       370        380        390        400        410        420 
INIIWPMILC GAGFGLFQSP NNHTIITSAP RERSGGASGM LGTARLLGQS SGAALVALML 

       430        440        450 
NQFGDNGTHV SLMAAAILAV IAACVSGLRI TQPRSRA

« Hide

References

[1]"A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map."
Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S. expand/collapse author list , Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y., Horiuchi T.
DNA Res. 3:379-392(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U00096 Genomic DNA. Translation: AAC74898.2.
AP009048 Genomic DNA. Translation: BAA15636.1.
RefSeqNP_416342.4. NC_000913.2.
YP_490090.1. NC_007779.1.

3D structure databases

ProteinModelPortalP76269.
ModBaseSearch...

Protein-protein interaction databases

STRING511145.b1828.

Protein family/group databases

TCDB2.A.1.3.17. major facilitator superfamily (MFS).

Proteomic databases

PaxDbP76269.
PRIDEP76269.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC74898; AAC74898; b1828.
BAA15636; BAA15636; BAA15636.
GeneID12930161.
946048.
KEGGecj:Y75_p1804.
eco:b1828.
PATRIC32118977. VBIEscCol129921_1906.

Organism-specific databases

EchoBASEEB3773.
EcoGeneEG14019. yebQ.

Phylogenomic databases

eggNOGCOG0477.
HOGENOMHOG000239125.
KOK08169.
OMAICTSICS.
ProtClustDBCLSK880224.

Enzyme and pathway databases

BioCycEcoCyc:B1828-MONOMER.
ECOL316407:JW5299-MONOMER.

Gene expression databases

GenevestigatorP76269.

Family and domain databases

InterProIPR011701. MFS.
IPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR001411. Tet-R_TetB/Drug-R_transptr.
[Graphical view]
PfamPF07690. MFS_1. 1 hit.
[Graphical view]
PRINTSPR01036. TCRTETB.
SUPFAMSSF103473. MFS_gen_substrate_transporter. 1 hit.
PROSITEPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYEBQ_ECOLI
AccessionPrimary (citable) accession number: P76269
Entry history
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: May 1, 2013
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

SIMILARITY comments

Index of protein domains and families

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