Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Inner membrane protein YeaI

Gene

yeaI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • negative regulation of bacterial-type flagellum-dependent cell motility Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G6971-MONOMER.
ECOL316407:JW1774-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane protein YeaI
Gene namesi
Name:yeaI
Ordered Locus Names:b1785, JW1774
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13495. yeaI.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2828PeriplasmicSequence analysisAdd
BLAST
Transmembranei29 – 4921HelicalSequence analysisAdd
BLAST
Topological domaini50 – 545CytoplasmicSequence analysis
Transmembranei55 – 7521HelicalSequence analysisAdd
BLAST
Topological domaini76 – 8914PeriplasmicSequence analysisAdd
BLAST
Transmembranei90 – 11021HelicalSequence analysisAdd
BLAST
Topological domaini111 – 12111CytoplasmicSequence analysisAdd
BLAST
Transmembranei122 – 14221HelicalSequence analysisAdd
BLAST
Topological domaini143 – 15816PeriplasmicSequence analysisAdd
BLAST
Transmembranei159 – 17921HelicalSequence analysisAdd
BLAST
Topological domaini180 – 19314CytoplasmicSequence analysisAdd
BLAST
Transmembranei194 – 21421HelicalSequence analysisAdd
BLAST
Topological domaini215 – 23622PeriplasmicSequence analysisAdd
BLAST
Transmembranei237 – 25721HelicalSequence analysisAdd
BLAST
Topological domaini258 – 2669CytoplasmicSequence analysis
Transmembranei267 – 28721HelicalSequence analysisAdd
BLAST
Topological domaini288 – 2936PeriplasmicSequence analysis
Transmembranei294 – 31421HelicalSequence analysisAdd
BLAST
Topological domaini315 – 491177CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 491491Inner membrane protein YeaIPRO_0000169015Add
BLAST

Proteomic databases

PaxDbiP76236.
PRIDEiP76236.

Expressioni

Inductioni

Induced by 0.3M NaCl in an RpoS-dependent fashion.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4260314. 18 interactions.
DIPiDIP-11788N.
IntActiP76236. 2 interactions.
MINTiMINT-1232043.
STRINGi511145.b1785.

Structurei

3D structure databases

ProteinModelPortaliP76236.
SMRiP76236. Positions 325-488.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini356 – 491136GGDEFPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 GGDEF domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4106KTS. Bacteria.
COG2199. LUCA.
HOGENOMiHOG000118907.
InParanoidiP76236.
OMAiSHAYLME.

Family and domain databases

CDDicd01949. GGDEF. 1 hit.
InterProiIPR000160. GGDEF_dom.
IPR033424. MASE4.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00990. GGDEF. 1 hit.
PF17158. MASE4. 1 hit.
[Graphical view]
SMARTiSM00267. GGDEF. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
TIGRFAMsiTIGR00254. GGDEF. 1 hit.
PROSITEiPS50887. GGDEF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P76236-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIQSTRISMG LFFKYFLSLT KIDPGQNYIS LPSIKSSTHI ALLFMVSMGT
60 70 80 90 100
QKLKAQSFFI FSLLLTLILF CITTLYNENT NVKLIPQMNY LMVVVALFFL
110 120 130 140 150
NAVIFLFMLM KYFTNKQILP TLILSLAFLS GLIYLVETIV IIHKPINGST
160 170 180 190 200
LIQTKSNDVS IFYIFRQLSF ICLTSLALFC YGKDNILDNN KKKTGILLLA
210 220 230 240 250
LIPFLVFPLL AHNLSSYNAD YSLYVVDYCP DNHTATWGIN YTKILVCLWA
260 270 280 290 300
FLLFFIIMRT RLASELWPLI ALLCLASLCC NLLLLTLDEY NYTIWYISRG
310 320 330 340 350
IEVSSKLFVV SFLIYNIFQE LQLSSKLAVH DVLTNIYNRR YFFNSVESLL
360 370 380 390 400
SRPVVKDFCV MLVDINQFKR INAQWGHRVG DKVLVSIVDI IQQSIRPDDI
410 420 430 440 450
LARLEGEVFG LLFTELNSAQ AKIIAERMRK NVELLTGFSN RYDVPEQMTI
460 470 480 490
SIGTVFSTGD TRNISLVMTE ADKALREAKS EGGNKVIIHH I
Length:491
Mass (Da):56,101
Last modified:February 1, 1997 - v1
Checksum:i2CF33E70FB6551AB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74855.1.
AP009048 Genomic DNA. Translation: BAA15586.1.
PIRiA64939.
RefSeqiNP_416299.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC74855; AAC74855; b1785.
BAA15586; BAA15586; BAA15586.
GeneIDi946366.
KEGGiecj:JW1774.
eco:b1785.
PATRICi32118881. VBIEscCol129921_1858.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74855.1.
AP009048 Genomic DNA. Translation: BAA15586.1.
PIRiA64939.
RefSeqiNP_416299.1. NC_000913.3.

3D structure databases

ProteinModelPortaliP76236.
SMRiP76236. Positions 325-488.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260314. 18 interactions.
DIPiDIP-11788N.
IntActiP76236. 2 interactions.
MINTiMINT-1232043.
STRINGi511145.b1785.

Proteomic databases

PaxDbiP76236.
PRIDEiP76236.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74855; AAC74855; b1785.
BAA15586; BAA15586; BAA15586.
GeneIDi946366.
KEGGiecj:JW1774.
eco:b1785.
PATRICi32118881. VBIEscCol129921_1858.

Organism-specific databases

EchoBASEiEB3268.
EcoGeneiEG13495. yeaI.

Phylogenomic databases

eggNOGiENOG4106KTS. Bacteria.
COG2199. LUCA.
HOGENOMiHOG000118907.
InParanoidiP76236.
OMAiSHAYLME.

Enzyme and pathway databases

BioCyciEcoCyc:G6971-MONOMER.
ECOL316407:JW1774-MONOMER.

Miscellaneous databases

PROiP76236.

Family and domain databases

CDDicd01949. GGDEF. 1 hit.
InterProiIPR000160. GGDEF_dom.
IPR033424. MASE4.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00990. GGDEF. 1 hit.
PF17158. MASE4. 1 hit.
[Graphical view]
SMARTiSM00267. GGDEF. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
TIGRFAMsiTIGR00254. GGDEF. 1 hit.
PROSITEiPS50887. GGDEF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYEAI_ECOLI
AccessioniPrimary (citable) accession number: P76236
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: September 7, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.