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Protein

Inner membrane ABC transporter permease protein YnjC

Gene

ynjC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Probably part of the binding-protein-dependent transport system YnjCD. Probably responsible for the translocation of the substrate across the membrane.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YNJC-MONOMER.
ECOL316407:JW5285-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane ABC transporter permease protein YnjC
Gene namesi
Name:ynjC
Ordered Locus Names:b1755, JW5285
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14005. ynjC.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 88CytoplasmicSequence analysis
Transmembranei9 – 2921HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini30 – 6233PeriplasmicSequence analysisAdd
BLAST
Transmembranei63 – 8321HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini84 – 918CytoplasmicSequence analysis
Transmembranei92 – 11221HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini113 – 13018PeriplasmicSequence analysisAdd
BLAST
Transmembranei131 – 15121HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini152 – 18938CytoplasmicSequence analysisAdd
BLAST
Transmembranei190 – 21021HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini211 – 23929PeriplasmicSequence analysisAdd
BLAST
Transmembranei240 – 26021HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini261 – 28424CytoplasmicSequence analysisAdd
BLAST
Transmembranei285 – 30521HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini306 – 31813PeriplasmicSequence analysisAdd
BLAST
Transmembranei319 – 33921HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini340 – 3456CytoplasmicSequence analysis
Transmembranei346 – 36621HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini367 – 3748PeriplasmicSequence analysis
Transmembranei375 – 39521HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini396 – 43237CytoplasmicSequence analysisAdd
BLAST
Transmembranei433 – 45321HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini454 – 48532PeriplasmicSequence analysisAdd
BLAST
Transmembranei486 – 50621HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini507 – 5115CytoplasmicSequence analysis

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 511511Inner membrane ABC transporter permease protein YnjCPRO_0000060263Add
BLAST

Proteomic databases

PaxDbiP76224.
PRIDEiP76224.

Interactioni

Protein-protein interaction databases

BioGridi4262127. 215 interactions.
STRINGi511145.b1755.

Structurei

3D structure databases

ProteinModelPortaliP76224.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini54 – 255202ABC transmembrane type-1 1PROSITE-ProRule annotationAdd
BLAST
Domaini315 – 496182ABC transmembrane type-1 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 ABC transmembrane type-1 domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CXZ. Bacteria.
COG4135. LUCA.
HOGENOMiHOG000275274.
KOiK05778.
OMAiESAFVLW.
OrthoDBiEOG6RRKK6.

Family and domain databases

Gene3Di1.10.3720.10. 2 hits.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 2 hits.
PROSITEiPS50928. ABC_TM1. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P76224-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATPLRYALI FLLWAMVAVI YAPLIPAALT LISPALSLTH WQALFADPQL
60 70 80 90 100
PQALLATLVS TTIAAVGALL IALLVIVALW PGPKWQRMCA RLPWLLAIPH
110 120 130 140 150
VAFATSALLL FADGGLLYDY FPYFTPPMDR FGIGLGLTLA VKESAFLLWI
160 170 180 190 200
LAAVLSEKWL LQQVIVLDSL GYSRWQCLNW LLLPSVAPAL AMAMLAIVAW
210 220 230 240 250
SLSVVDVAII LGPGNPPTLA VISWQWLTQG DIDQQTKGAL ASLLLMLLLA
260 270 280 290 300
AYVLLSYLLW RSWRRTIPRV DGVRKPATPL LPGNTLAIFL PLTGVLCVVL
310 320 330 340 350
LAILADQSTI NSEALINSLT MGLVATFIAL LLLLLWLEWG PQRRQLWLWL
360 370 380 390 400
PILLPALPLV AGQYTLALWL KLDGSWTAVV WGHLLWVMPW MLFILQPAWQ
410 420 430 440 450
RIDSRLILIA QTLGWSRAKI FFYVKCPLML RPVLIAFAVG FAVGIAQYMP
460 470 480 490 500
TLWLGAGRFP TLTTEAVALS SGGSNGILAA QALWQLLLPL IIFALTALVA
510
KWVGYVRQGL R
Length:511
Mass (Da):56,243
Last modified:December 15, 1998 - v2
Checksum:i07CDFCCE729BF369
GO

Sequence cautioni

The sequence BAA15546.2 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74825.2.
AP009048 Genomic DNA. Translation: BAA15546.2. Different initiation.
PIRiC64935.
RefSeqiNP_416269.4. NC_000913.3.
WP_000224958.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74825; AAC74825; b1755.
BAA15546; BAA15546; BAA15546.
GeneIDi946273.
KEGGiecj:JW5285.
eco:b1755.
PATRICi32118821. VBIEscCol129921_1828.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74825.2.
AP009048 Genomic DNA. Translation: BAA15546.2. Different initiation.
PIRiC64935.
RefSeqiNP_416269.4. NC_000913.3.
WP_000224958.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP76224.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262127. 215 interactions.
STRINGi511145.b1755.

Proteomic databases

PaxDbiP76224.
PRIDEiP76224.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74825; AAC74825; b1755.
BAA15546; BAA15546; BAA15546.
GeneIDi946273.
KEGGiecj:JW5285.
eco:b1755.
PATRICi32118821. VBIEscCol129921_1828.

Organism-specific databases

EchoBASEiEB3761.
EcoGeneiEG14005. ynjC.

Phylogenomic databases

eggNOGiENOG4105CXZ. Bacteria.
COG4135. LUCA.
HOGENOMiHOG000275274.
KOiK05778.
OMAiESAFVLW.
OrthoDBiEOG6RRKK6.

Enzyme and pathway databases

BioCyciEcoCyc:YNJC-MONOMER.
ECOL316407:JW5285-MONOMER.

Miscellaneous databases

PROiP76224.

Family and domain databases

Gene3Di1.10.3720.10. 2 hits.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 2 hits.
PROSITEiPS50928. ABC_TM1. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], SEQUENCE REVISION.
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYNJC_ECOLI
AccessioniPrimary (citable) accession number: P76224
Secondary accession number(s): P76908
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: December 15, 1998
Last modified: April 13, 2016
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.