P76205 (ARPB_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative ankyrin repeat protein B

Gene names

Name:	arpB
Ordered Locus Names:	b4494, JW5278/JW1710
ORF Names:	b1720/b1721

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	632 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Sequence similarities	Contains 3 ANK repeats.
Caution	Could be the product of a pseudogene. A frameshift in position 142 produces two separate ORFs.
Sequence caution	The sequence AP009048 differs from that shown. Reason: Frameshift at position 142. The sequence U00096 differs from that shown. Reason: Frameshift at position 142.

Ontologies

Keywords
Domain	ANK repeat Repeat
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 632	632	Putative ankyrin repeat protein B		PRO_0000067229
Regions
	Repeat	398 – 427	30	ANK 1
	Repeat	446 – 476	31	ANK 2
	Repeat	542 – 571	30	ANK 3

Sequences

	Sequence		Length	Mass (Da)
	P76205 [UniParc]. Last modified December 1, 2000. Version 2. Checksum: D16C65DAC90B34EC	FASTA	632	70,650
	10 20 30 40 50 60 MSQNDIIIRT HYKSPHRLHI DSDIPTPSSE PINQFARQLI TLLDTSDLSS MLSYCVTQEF 70 80 90 100 110 120 TANCRKISQN CYSTALFTIN FATSPIHTEN ILITLHYKKE IISLLLETTP IKANHLRSIL 130 140 150 160 170 180 DYIEQEQLTA EDRNHCMKLS KXSIEKKTIH PTVNLNGSAC FLQSPSDAIF CRHLSLQYAL 190 200 210 220 230 240 DSLRNGKGKV NLIKHYSSVE SIQQHVPLVR DAEFRALLRH PPAGSRVIAS KDFGFALDIF 250 260 270 280 290 300 FCRMMANNVS HMSAILYIDN HTLSVRLRIK QSVYGQLNYV VSVYDPNDTN VAVRDTHRTA 310 320 330 340 350 360 RGFLSLDKFI SSGPDAQTWA DRYVRNCAIA ILPLLPVGVP GAIFAGIASR MPFAPIHPSA 370 380 390 400 410 420 MLLIMATGQS QQLITLFKQL PILPEKEIIE IITAQNSVGT PALFLAMMNG HTDNVKIFMQ 430 440 450 460 470 480 EIQSLVDNHI IHEDNLVKLL QTKSANETPG LYISMLYGFD EIIDIFLNAL TTPIAQELLN 490 500 510 520 530 540 KKLVMSILAM KIHDGEPGLY AAMENNHPLC VTRFLSKING IAFKYKLSKA NIMDLLKGAT 550 560 570 580 590 600 AQGTPALYIA MSKGNEDVVL SYISTLGAFA KKHSFSQHQL FTLLAAKNHD NMSAVHIAIH 610 620 630 HKHYKTVETY YAAINAISQS LSFSADEIKT YL

References

[1]	"A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map." Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K. , Nakade S., Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y., Wada C., Yamamoto Y., Horiuchi T. DNA Res. 3:363-377(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00096 Genomic DNA. No translation available. AP009048 Genomic DNA. No translation available.
3D structure databases
ProteinModelPortal	P76205.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-9160N.
IntAct	P76205. 1 interaction.
Proteomic databases
PRIDE	P76205.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
EchoBASE	EB3739.
EcoGene	EG13983. arpB.
Phylogenomic databases
HOGENOM	HOG000051632.
Enzyme and pathway databases
BioCyc	EcoCyc:G6926-MONOMER. EcoCyc:G6927-MONOMER.
Gene expression databases
Genevestigator	P76205.
Family and domain databases
Gene3D	1.25.40.20. 1 hit.
InterPro	IPR002110. Ankyrin_rpt. IPR020683. Ankyrin_rpt-contain_dom. IPR012927. Toxin_15_N. [Graphical view]
Pfam	PF07906. Toxin_15. 1 hit. [Graphical view]
SMART	SM00248. ANK. 4 hits. [Graphical view]
SUPFAM	SSF48403. ANK. 1 hit.
PROSITE	PS50297. ANK_REP_REGION. False negative. PS50088. ANK_REPEAT. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ARPB_ECOLI

Accession

Primary (citable) accession number: P76205
Secondary accession number(s): P77764

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	May 29, 2013
This is version 86 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program