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Protein

Oxidoreductase YdhF

Gene

ydhF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May function as oxidoreductase.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei55Proton donorBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi158 – 159NADP1 Publication2
Nucleotide bindingi209 – 220NADP1 PublicationAdd BLAST12
Nucleotide bindingi263 – 264NADP1 Publication2

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NADP

Enzyme and pathway databases

BioCyciEcoCyc:G6887-MONOMER.
ECOL316407:JW1639-MONOMER.

Protein family/group databases

TCDBi8.A.5.1.7. the voltage-gated k(+) channel -subunit (kv) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Oxidoreductase YdhF (EC:1.-.-.-)
Gene namesi
Name:ydhF
Ordered Locus Names:b1647, JW1639
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13420. ydhF.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000703941 – 298Oxidoreductase YdhFAdd BLAST298

Proteomic databases

EPDiP76187.
PaxDbiP76187.
PRIDEiP76187.

Interactioni

Protein-protein interaction databases

BioGridi4263045. 12 interactors.
STRINGi511145.b1647.

Structurei

Secondary structure

1298
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi4 – 6Combined sources3
Beta strandi13 – 20Combined sources8
Turni22 – 28Combined sources7
Helixi31 – 44Combined sources14
Beta strandi48 – 50Combined sources3
Turni55 – 59Combined sources5
Helixi60 – 70Combined sources11
Helixi72 – 74Combined sources3
Turni75 – 77Combined sources3
Beta strandi79 – 84Combined sources6
Beta strandi91 – 93Combined sources3
Helixi103 – 117Combined sources15
Beta strandi122 – 127Combined sources6
Helixi136 – 148Combined sources13
Beta strandi155 – 159Combined sources5
Helixi162 – 169Combined sources8
Beta strandi179 – 182Combined sources4
Helixi189 – 191Combined sources3
Helixi195 – 202Combined sources8
Beta strandi207 – 209Combined sources3
Turni213 – 215Combined sources3
Beta strandi217 – 219Combined sources3
Helixi221 – 223Combined sources3
Helixi224 – 236Combined sources13
Helixi242 – 251Combined sources10
Beta strandi258 – 261Combined sources4
Helixi266 – 273Combined sources8
Helixi274 – 277Combined sources4
Helixi282 – 293Combined sources12

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1OG6X-ray2.80A/B/C2-298[»]
1UR3X-ray2.57M2-298[»]
ProteinModelPortaliP76187.
SMRiP76187.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP76187.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4107RGM. Bacteria.
COG4989. LUCA.
HOGENOMiHOG000250282.
InParanoidiP76187.
OMAiAGTMTWG.
PhylomeDBiP76187.

Family and domain databases

CDDicd06660. Aldo_ket_red. 1 hit.
Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 1 hit.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.

Sequencei

Sequence statusi: Complete.

P76187-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQRITIAPQ GPEFSRFVMG YWRLMDWNMS ARQLVSFIEE HLDLGVTTVD
60 70 80 90 100
HADIYGGYQC EAAFGEALKL APHLRERMEI VSKCGIATTA REENVIGHYI
110 120 130 140 150
TDRDHIIKSA EQSLINLATD HLDLLLIHRP DPLMDADEVA DAFKHLHQSG
160 170 180 190 200
KVRHFGVSNF TPAQFALLQS RLPFTLATNQ VEISPVHQPL LLDGTLDQLQ
210 220 230 240 250
QLRVRPMAWS CLGGGRLFND DYFQPLRDEL AVVAEELNAG SIEQVVYAWV
260 270 280 290
LRLPSQPLPI IGSGKIERVR AAVEAETLKM TRQQWFRIRK AALGYDVP
Length:298
Mass (Da):33,676
Last modified:October 11, 2004 - v2
Checksum:i984DACC2C04A6D9F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAT48134.1.
AP009048 Genomic DNA. Translation: BAE76490.1.
PIRiA64922.
RefSeqiWP_000250656.1. NZ_LN832404.1.
YP_025305.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAT48134; AAT48134; b1647.
BAE76490; BAE76490; BAE76490.
GeneIDi946960.
KEGGiecj:JW1639.
eco:b1647.
PATRICi32118596. VBIEscCol129921_1718.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAT48134.1.
AP009048 Genomic DNA. Translation: BAE76490.1.
PIRiA64922.
RefSeqiWP_000250656.1. NZ_LN832404.1.
YP_025305.1. NC_000913.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1OG6X-ray2.80A/B/C2-298[»]
1UR3X-ray2.57M2-298[»]
ProteinModelPortaliP76187.
SMRiP76187.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263045. 12 interactors.
STRINGi511145.b1647.

Protein family/group databases

TCDBi8.A.5.1.7. the voltage-gated k(+) channel -subunit (kv) family.

Proteomic databases

EPDiP76187.
PaxDbiP76187.
PRIDEiP76187.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT48134; AAT48134; b1647.
BAE76490; BAE76490; BAE76490.
GeneIDi946960.
KEGGiecj:JW1639.
eco:b1647.
PATRICi32118596. VBIEscCol129921_1718.

Organism-specific databases

EchoBASEiEB3196.
EcoGeneiEG13420. ydhF.

Phylogenomic databases

eggNOGiENOG4107RGM. Bacteria.
COG4989. LUCA.
HOGENOMiHOG000250282.
InParanoidiP76187.
OMAiAGTMTWG.
PhylomeDBiP76187.

Enzyme and pathway databases

BioCyciEcoCyc:G6887-MONOMER.
ECOL316407:JW1639-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP76187.
PROiP76187.

Family and domain databases

CDDicd06660. Aldo_ket_red. 1 hit.
Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 1 hit.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYDHF_ECOLI
AccessioniPrimary (citable) accession number: P76187
Secondary accession number(s): Q2MB66, Q6BF80
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: October 11, 2004
Last modified: November 2, 2016
This is version 118 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.