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Protein

Oxidoreductase YdhF

Gene

ydhF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May function as oxidoreductase.Curated

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei55 – 551Proton donorBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi158 – 1592NADP1 Publication
Nucleotide bindingi209 – 22012NADP1 PublicationAdd
BLAST
Nucleotide bindingi263 – 2642NADP1 Publication

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NADP

Enzyme and pathway databases

BioCyciEcoCyc:G6887-MONOMER.
ECOL316407:JW1639-MONOMER.

Protein family/group databases

TCDBi8.A.5.1.7. the voltage-gated k(+) channel -subunit (kv) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Oxidoreductase YdhF (EC:1.-.-.-)
Gene namesi
Name:ydhF
Ordered Locus Names:b1647, JW1639
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13420. ydhF.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 298298Oxidoreductase YdhFPRO_0000070394Add
BLAST

Proteomic databases

EPDiP76187.
PaxDbiP76187.
PRIDEiP76187.

Interactioni

Protein-protein interaction databases

BioGridi4263045. 12 interactions.
STRINGi511145.b1647.

Structurei

Secondary structure

1
298
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi4 – 63Combined sources
Beta strandi13 – 208Combined sources
Turni22 – 287Combined sources
Helixi31 – 4414Combined sources
Beta strandi48 – 503Combined sources
Turni55 – 595Combined sources
Helixi60 – 7011Combined sources
Helixi72 – 743Combined sources
Turni75 – 773Combined sources
Beta strandi79 – 846Combined sources
Beta strandi91 – 933Combined sources
Helixi103 – 11715Combined sources
Beta strandi122 – 1276Combined sources
Helixi136 – 14813Combined sources
Beta strandi155 – 1595Combined sources
Helixi162 – 1698Combined sources
Beta strandi179 – 1824Combined sources
Helixi189 – 1913Combined sources
Helixi195 – 2028Combined sources
Beta strandi207 – 2093Combined sources
Turni213 – 2153Combined sources
Beta strandi217 – 2193Combined sources
Helixi221 – 2233Combined sources
Helixi224 – 23613Combined sources
Helixi242 – 25110Combined sources
Beta strandi258 – 2614Combined sources
Helixi266 – 2738Combined sources
Helixi274 – 2774Combined sources
Helixi282 – 29312Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1OG6X-ray2.80A/B/C2-298[»]
1UR3X-ray2.57M2-298[»]
ProteinModelPortaliP76187.
SMRiP76187. Positions 1-297.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP76187.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4107RGM. Bacteria.
COG4989. LUCA.
HOGENOMiHOG000250282.
InParanoidiP76187.
OMAiAGTMTWG.
PhylomeDBiP76187.

Family and domain databases

CDDicd06660. Aldo_ket_red. 1 hit.
Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 1 hit.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.

Sequencei

Sequence statusi: Complete.

P76187-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQRITIAPQ GPEFSRFVMG YWRLMDWNMS ARQLVSFIEE HLDLGVTTVD
60 70 80 90 100
HADIYGGYQC EAAFGEALKL APHLRERMEI VSKCGIATTA REENVIGHYI
110 120 130 140 150
TDRDHIIKSA EQSLINLATD HLDLLLIHRP DPLMDADEVA DAFKHLHQSG
160 170 180 190 200
KVRHFGVSNF TPAQFALLQS RLPFTLATNQ VEISPVHQPL LLDGTLDQLQ
210 220 230 240 250
QLRVRPMAWS CLGGGRLFND DYFQPLRDEL AVVAEELNAG SIEQVVYAWV
260 270 280 290
LRLPSQPLPI IGSGKIERVR AAVEAETLKM TRQQWFRIRK AALGYDVP
Length:298
Mass (Da):33,676
Last modified:October 11, 2004 - v2
Checksum:i984DACC2C04A6D9F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAT48134.1.
AP009048 Genomic DNA. Translation: BAE76490.1.
PIRiA64922.
RefSeqiWP_000250656.1. NZ_LN832404.1.
YP_025305.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAT48134; AAT48134; b1647.
BAE76490; BAE76490; BAE76490.
GeneIDi946960.
KEGGiecj:JW1639.
eco:b1647.
PATRICi32118596. VBIEscCol129921_1718.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAT48134.1.
AP009048 Genomic DNA. Translation: BAE76490.1.
PIRiA64922.
RefSeqiWP_000250656.1. NZ_LN832404.1.
YP_025305.1. NC_000913.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1OG6X-ray2.80A/B/C2-298[»]
1UR3X-ray2.57M2-298[»]
ProteinModelPortaliP76187.
SMRiP76187. Positions 1-297.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263045. 12 interactions.
STRINGi511145.b1647.

Protein family/group databases

TCDBi8.A.5.1.7. the voltage-gated k(+) channel -subunit (kv) family.

Proteomic databases

EPDiP76187.
PaxDbiP76187.
PRIDEiP76187.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT48134; AAT48134; b1647.
BAE76490; BAE76490; BAE76490.
GeneIDi946960.
KEGGiecj:JW1639.
eco:b1647.
PATRICi32118596. VBIEscCol129921_1718.

Organism-specific databases

EchoBASEiEB3196.
EcoGeneiEG13420. ydhF.

Phylogenomic databases

eggNOGiENOG4107RGM. Bacteria.
COG4989. LUCA.
HOGENOMiHOG000250282.
InParanoidiP76187.
OMAiAGTMTWG.
PhylomeDBiP76187.

Enzyme and pathway databases

BioCyciEcoCyc:G6887-MONOMER.
ECOL316407:JW1639-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP76187.
PROiP76187.

Family and domain databases

CDDicd06660. Aldo_ket_red. 1 hit.
Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 1 hit.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYDHF_ECOLI
AccessioniPrimary (citable) accession number: P76187
Secondary accession number(s): Q2MB66, Q6BF80
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: October 11, 2004
Last modified: September 7, 2016
This is version 117 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.