Skip Header

Contribute Send feedback
Read comments (?) or add your own

P76186 (YDHK_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized transporter YdhK
Gene names
Name:ydhK
Ordered Locus Names:b1645, JW1637
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length670 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Subcellular location

Cell membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family. [View classification]

Ontologies

Keywords
   Biological processTransport
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtransport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 670670Uncharacterized transporter YdhK
PRO_0000210093

Regions

Transmembrane23 – 4220Helical; Potential
Transmembrane47 – 6923Helical; Potential
Transmembrane76 – 9823Helical; Potential
Transmembrane118 – 14023Helical; Potential
Transmembrane153 – 17018Helical; Potential
Transmembrane381 – 40323Helical; Potential
Transmembrane410 – 43223Helical; Potential
Transmembrane437 – 45418Helical; Potential
Transmembrane461 – 48323Helical; Potential
Transmembrane493 – 51018Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P76186 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 285C136651DD5EFA

FASTA67075,267
        10         20         30         40         50         60 
MNASSWSLRN LPWFRATLAQ WRYALRNTIA MCLALTVAYY LNLDEPYWAM TSAAVVSFPT 

        70         80         90        100        110        120 
VGGVISKSLG RIAGSLLGAI AALLLAGHTL NEPWFFLLSM SAWLGFCTWA CAHFTNNVAY 

       130        140        150        160        170        180 
AFQLAGYTAA IIAFPMVNIT EASQLWDIAQ ARVCEVIVGI LCGGMMMMIL PSSSDATALL 

       190        200        210        220        230        240 
TALKNMHARL LEHASLLWQP ETTDAIRAAH EGVIGQILTM NLLRIQAFWS HYRFRQQNAR 

       250        260        270        280        290        300 
LNALLHQQLR MTSVISSLRR MLLNWPSPPG ATREILEQLL TALASSQTDV YTVARIIAPL 

       310        320        330        340        350        360 
RPTNVADYRH VAFWQRLRYF CRLYLQSSQE LHRLQSGVDD HTRLPRTSGL ARHTDNAEAM 

       370        380        390        400        410        420 
WSGLRTFCTL MMIGAWSIAS QWDAGANALT LAAISCVLYS AVAAPFKSLS LLMRTLVLLS 

       430        440        450        460        470        480 
LFSFVVKFGL MVQISDLWQF LLFLFPLLAT MQLLKLQMPK FAALWGQLIV FMGSFIAVTN 

       490        500        510        520        530        540 
PPVYDFADFL NDNLAKIVGV ALAWLAFAIL RPGSDARKSR RHIRALRRDF VDQLSRHPTL 

       550        560        570        580        590        600 
SESEFESLTY HHVSQLSNSQ DALARRWLLR WGVVLLNCSH VVWQLRDWES RSDPLSRVRD 

       610        620        630        640        650        660 
NCISLLRGVM SERGVQQKSL AATLEELQRI CDSLARHHQP AARELAAIVW RLYCSLSQLE 

       670 
QAPPQGTLAS

« Hide

References

[1]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[2]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[3]"A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map."
Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K. expand/collapse author list , Nakade S., Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y., Wada C., Yamamoto Y., Horiuchi T.
DNA Res. 3:363-377(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-169.
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U00096 Genomic DNA. Translation: AAC74717.1.
AP009048 Genomic DNA. Translation: BAA15405.1.
PIRG64921.
RefSeqNP_416162.1. NC_000913.2.
YP_489909.1. NC_007779.1.

3D structure databases

ProteinModelPortalP76186.
ModBaseSearch...

Protein-protein interaction databases

IntActP76186. 4 interactions.
STRING511145.b1645.

Proteomic databases

PRIDEP76186.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC74717; AAC74717; b1645.
BAA15405; BAA15405; BAA15405.
GeneID12934054.
946528.
KEGGecj:Y75_p1622.
eco:b1645.
PATRIC32118592. VBIEscCol129921_1716.

Organism-specific databases

EchoBASEEB3703.
EcoGeneEG13945. ydhK.

Phylogenomic databases

eggNOGCOG1289.
HOGENOMHOG000283450.
OMARQNNVLN.
ProtClustDBCLSK880154.

Enzyme and pathway databases

BioCycEcoCyc:G6885-MONOMER.
ECOL316407:JW1637-MONOMER.

Gene expression databases

GenevestigatorP76186.

Family and domain databases

InterProIPR006726. PHBA_efflux_AaeB/fusaric-R.
[Graphical view]
PfamPF04632. FUSC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYDHK_ECOLI
AccessionPrimary (citable) accession number: P76186
Secondary accession number(s): P76894
Entry history
Integrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: February 1, 1997
Last modified: May 1, 2013
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents