Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Anaerobic dimethyl sulfoxide reductase chain YnfH

Gene

ynfH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. The C subunit anchors the other two subunits to the membrane and stabilize the catalytic subunits (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciEcoCyc:G6848-MONOMER.
ECOL316407:JW5261-MONOMER.
MetaCyc:G6848-MONOMER.

Protein family/group databases

TCDBi5.A.3.3.1. the prokaryotic molybdopterin-containing oxidoreductase (pmo) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Anaerobic dimethyl sulfoxide reductase chain YnfH
Alternative name(s):
DMSO reductase anchor subunit YnfH
Gene namesi
Name:ynfH
Ordered Locus Names:b1590, JW5261
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13846. ynfH.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 9PeriplasmicSequence analysis9
Transmembranei10 – 30HelicalSequence analysisAdd BLAST21
Topological domaini31 – 45CytoplasmicSequence analysisAdd BLAST15
Transmembranei46 – 66HelicalSequence analysisAdd BLAST21
Topological domaini67 – 86PeriplasmicSequence analysisAdd BLAST20
Transmembranei87 – 107HelicalSequence analysisAdd BLAST21
Topological domaini108 – 115CytoplasmicSequence analysis8
Transmembranei116 – 136HelicalSequence analysisAdd BLAST21
Topological domaini137 – 148PeriplasmicSequence analysisAdd BLAST12
Transmembranei149 – 169HelicalSequence analysisAdd BLAST21
Topological domaini170 – 180CytoplasmicSequence analysisAdd BLAST11
Transmembranei181 – 201HelicalSequence analysisAdd BLAST21
Topological domaini202 – 222PeriplasmicSequence analysisAdd BLAST21
Transmembranei223 – 243HelicalSequence analysisAdd BLAST21
Topological domaini244 – 250CytoplasmicSequence analysis7
Transmembranei251 – 271HelicalSequence analysisAdd BLAST21
Topological domaini272 – 284PeriplasmicSequence analysisAdd BLAST13

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001689671 – 284Anaerobic dimethyl sulfoxide reductase chain YnfHAdd BLAST284

Proteomic databases

PaxDbiP76173.
PRIDEiP76173.

Interactioni

Subunit structurei

The complex consists of three subunits: YnfF, the reductase; YnfG, an electron transfer protein, and YnfH, a membrane anchor protein.Curated

Protein-protein interaction databases

BioGridi4263479. 7 interactors.
STRINGi511145.b1590.

Structurei

3D structure databases

ProteinModelPortaliP76173.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

To E.coli DmsC.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107KGK. Bacteria.
COG3302. LUCA.
HOGENOMiHOG000118381.
KOiK07312.
OMAiMTRVYQI.

Family and domain databases

InterProiIPR007059. DmsC.
[Graphical view]
PfamiPF04976. DmsC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P76173-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNGWHEWPL VIFTVLGQCV VGALIVSGIG WFAAKNDADR QRIVRGMFFL
60 70 80 90 100
WLLMGVGFIA SVMHLGSPLR AFNSLNRIGA SGLSNEIAAG SIFFAVGGLW
110 120 130 140 150
WLVAVIGKMP QALGKLWLLF SMALGVIFVW MMTCVYQIDT VPTWHNGYTT
160 170 180 190 200
LAFFLTVLLS GPILAAAILR AARVTFNTTP FAIISVLALI ACAGVIVLQG
210 220 230 240 250
LSLASIHSSV QQASALVPDY ASLQVWRVVL LCAGLGCWLC PLIRRREPHV
260 270 280
AGLILGLILI LGGEMIGRVL FYGLHMTVGM AIAG
Length:284
Mass (Da):30,524
Last modified:February 1, 1997 - v1
Checksum:i73F7D760FC4B1344
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74662.1.
AP009048 Genomic DNA. Translation: BAA15314.2.
PIRiH64914.
RefSeqiNP_416107.1. NC_000913.3.
WP_000526503.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74662; AAC74662; b1590.
BAA15314; BAA15314; BAA15314.
GeneIDi945822.
KEGGiecj:JW5261.
eco:b1590.
PATRICi32118482. VBIEscCol129921_1661.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74662.1.
AP009048 Genomic DNA. Translation: BAA15314.2.
PIRiH64914.
RefSeqiNP_416107.1. NC_000913.3.
WP_000526503.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP76173.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263479. 7 interactors.
STRINGi511145.b1590.

Protein family/group databases

TCDBi5.A.3.3.1. the prokaryotic molybdopterin-containing oxidoreductase (pmo) family.

Proteomic databases

PaxDbiP76173.
PRIDEiP76173.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74662; AAC74662; b1590.
BAA15314; BAA15314; BAA15314.
GeneIDi945822.
KEGGiecj:JW5261.
eco:b1590.
PATRICi32118482. VBIEscCol129921_1661.

Organism-specific databases

EchoBASEiEB3607.
EcoGeneiEG13846. ynfH.

Phylogenomic databases

eggNOGiENOG4107KGK. Bacteria.
COG3302. LUCA.
HOGENOMiHOG000118381.
KOiK07312.
OMAiMTRVYQI.

Enzyme and pathway databases

BioCyciEcoCyc:G6848-MONOMER.
ECOL316407:JW5261-MONOMER.
MetaCyc:G6848-MONOMER.

Miscellaneous databases

PROiP76173.

Family and domain databases

InterProiIPR007059. DmsC.
[Graphical view]
PfamiPF04976. DmsC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYNFH_ECOLI
AccessioniPrimary (citable) accession number: P76173
Secondary accession number(s): P77142
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.