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P76173 (YNFH_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Anaerobic dimethyl sulfoxide reductase chain YnfH
Alternative name(s):
DMSO reductase anchor subunit YnfH
Gene names
Name:ynfH
Ordered Locus Names:b1590, JW5261
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length284 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. The C subunit anchors the other two subunits to the membrane and stabilize the catalytic subunits By similarity.

Subunit structure

The complex consists of three subunits: YnfF, the reductase; YnfG, an electron transfer protein, and YnfH, a membrane anchor protein Potential.

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

To E.coli DmsC.

Ontologies

Keywords
   Cellular componentCell inner membrane
Cell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processanaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionoxidoreductase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 284284Anaerobic dimethyl sulfoxide reductase chain YnfH
PRO_0000168967

Regions

Topological domain1 – 99Periplasmic Potential
Transmembrane10 – 3021Helical; Potential
Topological domain31 – 4515Cytoplasmic Potential
Transmembrane46 – 6621Helical; Potential
Topological domain67 – 8620Periplasmic Potential
Transmembrane87 – 10721Helical; Potential
Topological domain108 – 1158Cytoplasmic Potential
Transmembrane116 – 13621Helical; Potential
Topological domain137 – 14812Periplasmic Potential
Transmembrane149 – 16921Helical; Potential
Topological domain170 – 18011Cytoplasmic Potential
Transmembrane181 – 20121Helical; Potential
Topological domain202 – 22221Periplasmic Potential
Transmembrane223 – 24321Helical; Potential
Topological domain244 – 2507Cytoplasmic Potential
Transmembrane251 – 27121Helical; Potential
Topological domain272 – 28413Periplasmic Potential

Sequences

Sequence LengthMass (Da)Tools
P76173 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 73F7D760FC4B1344

FASTA28430,524
        10         20         30         40         50         60 
MGNGWHEWPL VIFTVLGQCV VGALIVSGIG WFAAKNDADR QRIVRGMFFL WLLMGVGFIA 

        70         80         90        100        110        120 
SVMHLGSPLR AFNSLNRIGA SGLSNEIAAG SIFFAVGGLW WLVAVIGKMP QALGKLWLLF 

       130        140        150        160        170        180 
SMALGVIFVW MMTCVYQIDT VPTWHNGYTT LAFFLTVLLS GPILAAAILR AARVTFNTTP 

       190        200        210        220        230        240 
FAIISVLALI ACAGVIVLQG LSLASIHSSV QQASALVPDY ASLQVWRVVL LCAGLGCWLC 

       250        260        270        280 
PLIRRREPHV AGLILGLILI LGGEMIGRVL FYGLHMTVGM AIAG

« Hide

References

[1]"A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map."
Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K. expand/collapse author list , Nakade S., Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y., Wada C., Yamamoto Y., Horiuchi T.
DNA Res. 3:363-377(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U00096 Genomic DNA. Translation: AAC74662.1.
AP009048 Genomic DNA. Translation: BAA15314.2.
PIRH64914.
RefSeqNP_416107.1. NC_000913.2.
YP_489853.1. NC_007779.1.

3D structure databases

ProteinModelPortalP76173.
ModBaseSearch...

Protein-protein interaction databases

STRING511145.b1590.

Protein family/group databases

TCDB5.A.3.3.1. prokaryotic molybdopterin-containing oxidoreductase (PMO) family.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC74662; AAC74662; b1590.
BAA15314; BAA15314; BAA15314.
GeneID12934485.
945822.
KEGGecj:Y75_p1566.
eco:b1590.
PATRIC32118482. VBIEscCol129921_1661.

Organism-specific databases

EchoBASEEB3607.
EcoGeneEG13846. ynfH.

Phylogenomic databases

eggNOGCOG3302.
HOGENOMHOG000118381.
KOK07312.
OMAWAMTRVY.
ProtClustDBCLSK870602.

Enzyme and pathway databases

BioCycEcoCyc:G6848-MONOMER.
ECOL316407:JW5261-MONOMER.
MetaCyc:G6848-MONOMER.

Gene expression databases

GenevestigatorP76173.

Family and domain databases

InterProIPR007059. DmsC.
[Graphical view]
PfamPF04976. DmsC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYNFH_ECOLI
AccessionPrimary (citable) accession number: P76173
Secondary accession number(s): P77142
Entry history
Integrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: February 1, 1997
Last modified: May 1, 2013
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

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