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Protein

UPF0060 membrane protein YnfA

Gene

ynfA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:G6840-MONOMER.
ECOL316407:JW1574-MONOMER.

Protein family/group databases

TCDBi2.A.7.26.1. the drug/metabolite transporter (dmt) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0060 membrane protein YnfAUniRule annotation
Gene namesi
Name:ynfAUniRule annotation
Ordered Locus Names:b1582, JW1574
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13839. ynfA.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 5PeriplasmicUniRule annotation5
Transmembranei6 – 26HelicalUniRule annotationAdd BLAST21
Topological domaini27 – 30CytoplasmicUniRule annotation4
Transmembranei31 – 51HelicalUniRule annotationAdd BLAST21
Topological domaini52 – 60PeriplasmicUniRule annotation9
Transmembranei61 – 81HelicalUniRule annotationAdd BLAST21
Topological domaini82 – 84CytoplasmicUniRule annotation3
Transmembranei85 – 105HelicalUniRule annotationAdd BLAST21
Topological domaini106 – 108PeriplasmicUniRule annotation3

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoliWiki
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001623291 – 108UPF0060 membrane protein YnfAAdd BLAST108

Proteomic databases

PaxDbiP76169.
PRIDEiP76169.

Interactioni

Protein-protein interaction databases

BioGridi4260820. 20 interactors.
STRINGi511145.b1582.

Structurei

3D structure databases

ProteinModelPortaliP76169.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0060 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105KK4. Bacteria.
COG1742. LUCA.
HOGENOMiHOG000223633.
InParanoidiP76169.
KOiK09771.
OMAiTPDLYDW.
PhylomeDBiP76169.

Family and domain databases

HAMAPiMF_00010. UPF0060. 1 hit.
InterProiIPR003844. UPF0060.
[Graphical view]
PfamiPF02694. UPF0060. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P76169-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKTTLLFFA TALCEIIGCF LPWLWLKRNA SIWLLLPAGI SLALFVWLLT
60 70 80 90 100
LHPAASGRVY AAYGGVYVCT ALMWLRVVDG VKLTLYDWTG ALIALCGMLI

IVAGWGRT
Length:108
Mass (Da):11,920
Last modified:February 1, 1997 - v1
Checksum:i16319B7E35F2D1AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74654.1.
AP009048 Genomic DNA. Translation: BAE76476.1.
PIRiH64913.
RefSeqiNP_416099.1. NC_000913.3.
WP_000598292.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74654; AAC74654; b1582.
BAE76476; BAE76476; BAE76476.
GeneIDi946125.
KEGGiecj:JW1574.
eco:b1582.
PATRICi32118466. VBIEscCol129921_1653.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74654.1.
AP009048 Genomic DNA. Translation: BAE76476.1.
PIRiH64913.
RefSeqiNP_416099.1. NC_000913.3.
WP_000598292.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP76169.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260820. 20 interactors.
STRINGi511145.b1582.

Protein family/group databases

TCDBi2.A.7.26.1. the drug/metabolite transporter (dmt) superfamily.

Proteomic databases

PaxDbiP76169.
PRIDEiP76169.

Protocols and materials databases

DNASUi946125.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74654; AAC74654; b1582.
BAE76476; BAE76476; BAE76476.
GeneIDi946125.
KEGGiecj:JW1574.
eco:b1582.
PATRICi32118466. VBIEscCol129921_1653.

Organism-specific databases

EchoBASEiEB3600.
EcoGeneiEG13839. ynfA.

Phylogenomic databases

eggNOGiENOG4105KK4. Bacteria.
COG1742. LUCA.
HOGENOMiHOG000223633.
InParanoidiP76169.
KOiK09771.
OMAiTPDLYDW.
PhylomeDBiP76169.

Enzyme and pathway databases

BioCyciEcoCyc:G6840-MONOMER.
ECOL316407:JW1574-MONOMER.

Miscellaneous databases

PROiP76169.

Family and domain databases

HAMAPiMF_00010. UPF0060. 1 hit.
InterProiIPR003844. UPF0060.
[Graphical view]
PfamiPF02694. UPF0060. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYNFA_ECOLI
AccessioniPrimary (citable) accession number: P76169
Secondary accession number(s): Q2MB80
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.