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Protein

Antitermination protein Q homolog from lambdoid prophage Qin

Gene

quuQ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Positively regulate expression of some phage genes. Bacterial host RNA polymerase modified by antitermination proteins transcribes through termination sites that otherwise prevent expression of the regulated genes (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription antitermination, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6830-MONOMER.
ECOL316407:JW1551-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Antitermination protein Q homolog from lambdoid prophage Qin
Gene namesi
Name:quuQ
Synonyms:ydfT
Ordered Locus Names:b1559, JW1551
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13832. quuQ.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 250250Antitermination protein Q homolog from lambdoid prophage QinPRO_0000073896Add
BLAST

Proteomic databases

PaxDbiP76161.

Interactioni

Protein-protein interaction databases

BioGridi4261260. 12 interactions.
DIPiDIP-28061N.
IntActiP76161. 5 interactions.
STRINGi511145.b1559.

Structurei

3D structure databases

ProteinModelPortaliP76161.
SMRiP76161. Positions 150-249.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105HGD. Bacteria.
ENOG410ZK5A. LUCA.
HOGENOMiHOG000119997.
OMAiWEKELCQ.
OrthoDBiEOG6FNHM0.

Family and domain databases

Gene3Di2.10.230.10. 1 hit.
InterProiIPR003222. Antitermntn.
IPR001305. HSP_DnaJ_Cys-rich_dom.
[Graphical view]
PfamiPF03589. Antiterm. 2 hits.
[Graphical view]
SUPFAMiSSF57938. SSF57938. 1 hit.

Sequencei

Sequence statusi: Complete.

P76161-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLEALPKYY SPKSPKLSDD APATGTGCLT ITDVMAAQGM VQSKAPLGLA
60 70 80 90 100
LFLAKVGVQD PQFAIEGLLN YAMALDNPTL NKLSEEIRLQ IIPYLVSFAF
110 120 130 140 150
ADYSRSAASK ARCEHCSGTG FYNVLREVVK HYRRGESVIK EEWVKELCQH
160 170 180 190 200
CHGKGEASTA CRGCKGKGIV LDEKRTRFHG VPVYKICGRC NGNRFSRLPT
210 220 230 240 250
TLARRHVQKL VPDLTDYQWY KGYADVIGKL VTKCWQEEAY AEAQLRKVTR
Length:250
Mass (Da):27,926
Last modified:April 27, 2001 - v2
Checksum:i275509A4E615F862
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74632.2.
AP009048 Genomic DNA. Translation: BAA15258.1.
PIRiB64911.
RefSeqiNP_416077.4. NC_000913.3.
WP_001047135.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74632; AAC74632; b1559.
BAA15258; BAA15258; BAA15258.
GeneIDi946103.
KEGGiecj:JW1551.
eco:b1559.
PATRICi32118420. VBIEscCol129921_1630.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74632.2.
AP009048 Genomic DNA. Translation: BAA15258.1.
PIRiB64911.
RefSeqiNP_416077.4. NC_000913.3.
WP_001047135.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP76161.
SMRiP76161. Positions 150-249.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261260. 12 interactions.
DIPiDIP-28061N.
IntActiP76161. 5 interactions.
STRINGi511145.b1559.

Proteomic databases

PaxDbiP76161.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74632; AAC74632; b1559.
BAA15258; BAA15258; BAA15258.
GeneIDi946103.
KEGGiecj:JW1551.
eco:b1559.
PATRICi32118420. VBIEscCol129921_1630.

Organism-specific databases

EchoBASEiEB3593.
EcoGeneiEG13832. quuQ.

Phylogenomic databases

eggNOGiENOG4105HGD. Bacteria.
ENOG410ZK5A. LUCA.
HOGENOMiHOG000119997.
OMAiWEKELCQ.
OrthoDBiEOG6FNHM0.

Enzyme and pathway databases

BioCyciEcoCyc:G6830-MONOMER.
ECOL316407:JW1551-MONOMER.

Miscellaneous databases

PROiP76161.

Family and domain databases

Gene3Di2.10.230.10. 1 hit.
InterProiIPR003222. Antitermntn.
IPR001305. HSP_DnaJ_Cys-rich_dom.
[Graphical view]
PfamiPF03589. Antiterm. 2 hits.
[Graphical view]
SUPFAMiSSF57938. SSF57938. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiREQ2_ECOLI
AccessioniPrimary (citable) accession number: P76161
Secondary accession number(s): P77604
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: January 20, 2016
This is version 117 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.