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Protein

HTH-type transcriptional regulator YdeO

Gene

ydeO

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Induces the expression of gadE and mdtEF. Could also regulate the expression of other genes involved in acid resistance.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi153 – 172H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

  • positive regulation of transcription, DNA-templated Source: EcoCyc
  • transcription, DNA-templated Source: EcoCyc
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6789-MONOMER.
ECOL316407:JW1494-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator YdeO
Gene namesi
Name:ydeO
Ordered Locus Names:b1499, JW1494
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13797. ydeO.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001946061 – 253HTH-type transcriptional regulator YdeOAdd BLAST253

Proteomic databases

PaxDbiP76135.
PRIDEiP76135.

Expressioni

Inductioni

Induced by EvgA.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4260212. 7 interactors.
IntActiP76135. 1 interactor.
STRINGi511145.b1499.

Structurei

3D structure databases

ProteinModelPortaliP76135.
SMRiP76135.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 HTH araC/xylS-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105Z68. Bacteria.
COG2207. LUCA.
HOGENOMiHOG000120708.
InParanoidiP76135.
OMAiHMGMNTG.
PhylomeDBiP76135.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P76135-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLVCSVIFI HHAFNANILD KDYAFSDGEI LMVDNAVRTH FEPYERHFKE
60 70 80 90 100
IGFTENTIKK YLQCTNIQTV TVPVPAKFLR ASNVPTGLLN EMIAYLNSEE
110 120 130 140 150
RNHHNFSELL LFSCLSIFAA CKGFITLLTN GVLSVSGKVR NIVNMKPAHP
160 170 180 190 200
WKLKDICDCL YISESLLKKK LKQEQTTFSQ ILLDARMQHA KNLIRVEGSV
210 220 230 240 250
NKIAEQCGYA STSYFIYAFR KHFGNSPKRV SKEYRCQSHT GMNTGNTMNA

LAI
Length:253
Mass (Da):28,725
Last modified:February 1, 1997 - v1
Checksum:i6898BBAA54DAA997
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74572.1.
AP009048 Genomic DNA. Translation: BAA15173.2.
PIRiF64903.
RefSeqiNP_416016.1. NC_000913.3.
WP_000060495.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74572; AAC74572; b1499.
BAA15173; BAA15173; BAA15173.
GeneIDi945922.
KEGGiecj:JW1494.
eco:b1499.
PATRICi32118292. VBIEscCol129921_1566.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74572.1.
AP009048 Genomic DNA. Translation: BAA15173.2.
PIRiF64903.
RefSeqiNP_416016.1. NC_000913.3.
WP_000060495.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP76135.
SMRiP76135.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260212. 7 interactors.
IntActiP76135. 1 interactor.
STRINGi511145.b1499.

Proteomic databases

PaxDbiP76135.
PRIDEiP76135.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74572; AAC74572; b1499.
BAA15173; BAA15173; BAA15173.
GeneIDi945922.
KEGGiecj:JW1494.
eco:b1499.
PATRICi32118292. VBIEscCol129921_1566.

Organism-specific databases

EchoBASEiEB3558.
EcoGeneiEG13797. ydeO.

Phylogenomic databases

eggNOGiENOG4105Z68. Bacteria.
COG2207. LUCA.
HOGENOMiHOG000120708.
InParanoidiP76135.
OMAiHMGMNTG.
PhylomeDBiP76135.

Enzyme and pathway databases

BioCyciEcoCyc:G6789-MONOMER.
ECOL316407:JW1494-MONOMER.

Miscellaneous databases

PROiP76135.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYDEO_ECOLI
AccessioniPrimary (citable) accession number: P76135
Secondary accession number(s): P76877
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.