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Protein

Uncharacterized protein YncE

Gene

yncE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • DNA binding Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G6763-MONOMER.
ECOL316407:JW1447-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YncE
Gene namesi
Name:yncE
Ordered Locus Names:b1452, JW1447
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13775. yncE.

Subcellular locationi

GO - Cellular componenti

  • outer membrane-bounded periplasmic space Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3030Sequence analysisAdd
BLAST
Chaini31 – 353323Uncharacterized protein YncEPRO_0000013838Add
BLAST

Proteomic databases

EPDiP76116.
PaxDbiP76116.
PRIDEiP76116.

Expressioni

Inductioni

Repressed by Fur.1 Publication

Interactioni

Subunit structurei

Monomer.1 Publication

Protein-protein interaction databases

BioGridi4260198. 4 interactions.
DIPiDIP-28079N.
IntActiP76116. 4 interactions.
STRINGi511145.b1452.

Structurei

Secondary structure

1
353
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi34 – 4916Combined sources
Turni50 – 534Combined sources
Beta strandi54 – 596Combined sources
Turni63 – 653Combined sources
Beta strandi66 – 749Combined sources
Turni76 – 783Combined sources
Beta strandi81 – 899Combined sources
Beta strandi93 – 975Combined sources
Turni98 – 1014Combined sources
Beta strandi102 – 1076Combined sources
Turni108 – 1114Combined sources
Beta strandi112 – 1176Combined sources
Turni118 – 1203Combined sources
Beta strandi123 – 1297Combined sources
Beta strandi142 – 1498Combined sources
Turni150 – 1534Combined sources
Beta strandi154 – 16310Combined sources
Beta strandi165 – 1706Combined sources
Turni171 – 1744Combined sources
Beta strandi175 – 1806Combined sources
Beta strandi191 – 1933Combined sources
Turni194 – 1974Combined sources
Beta strandi198 – 2025Combined sources
Beta strandi206 – 2127Combined sources
Turni213 – 2164Combined sources
Beta strandi217 – 2237Combined sources
Beta strandi227 – 2293Combined sources
Beta strandi233 – 2397Combined sources
Turni240 – 2434Combined sources
Beta strandi244 – 25916Combined sources
Turni260 – 2623Combined sources
Beta strandi265 – 2706Combined sources
Beta strandi277 – 2804Combined sources
Turni281 – 2844Combined sources
Beta strandi285 – 2906Combined sources
Turni291 – 2944Combined sources
Beta strandi295 – 3006Combined sources
Turni301 – 3044Combined sources
Beta strandi305 – 3117Combined sources
Beta strandi314 – 3218Combined sources
Beta strandi327 – 3337Combined sources
Beta strandi338 – 3403Combined sources
Beta strandi346 – 3527Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3VGZX-ray1.70A/B/C/D1-353[»]
3VH0X-ray2.90A/B/C/D1-353[»]
ProteinModelPortaliP76116.
SMRiP76116. Positions 31-353.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4108NS2. Bacteria.
COG3391. LUCA.
HOGENOMiHOG000120631.
InParanoidiP76116.
OMAiQDDGKEH.
OrthoDBiEOG6VXF6Q.
PhylomeDBiP76116.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR011048. Haem_d1.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
SUPFAMiSSF51004. SSF51004. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P76116-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHLRHLFSSR LRGSLLLGSL LVVSSFSTQA AEEMLRKAVG KGAYEMAYSQ
60 70 80 90 100
QENALWLATS QSRKLDKGGV VYRLDPVTLE VTQAIHNDLK PFGATINNTT
110 120 130 140 150
QTLWFGNTVN SAVTAIDAKT GEVKGRLVLD DRKRTEEVRP LQPRELVADD
160 170 180 190 200
ATNTVYISGI GKESVIWVVD GGNIKLKTAI QNTGKMSTGL ALDSEGKRLY
210 220 230 240 250
TTNADGELIT IDTADNKILS RKKLLDDGKE HFFINISLDT ARQRAFITDS
260 270 280 290 300
KAAEVLVVDT RNGNILAKVA APESLAVLFN PARNEAYVTH RQAGKVSVID
310 320 330 340 350
AKSYKVVKTF DTPTHPNSLA LSADGKTLYV SVKQKSTKQQ EATQPDDVIR

IAL
Length:353
Mass (Da):38,613
Last modified:February 1, 1997 - v1
Checksum:iF0CA76C737035671
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74534.1.
AP009048 Genomic DNA. Translation: BAE76445.1.
PIRiG64897.
RefSeqiNP_415969.1. NC_000913.3.
WP_000550695.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74534; AAC74534; b1452.
BAE76445; BAE76445; BAE76445.
GeneIDi946006.
KEGGiecj:JW1447.
eco:b1452.
PATRICi32118196. VBIEscCol129921_1518.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74534.1.
AP009048 Genomic DNA. Translation: BAE76445.1.
PIRiG64897.
RefSeqiNP_415969.1. NC_000913.3.
WP_000550695.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3VGZX-ray1.70A/B/C/D1-353[»]
3VH0X-ray2.90A/B/C/D1-353[»]
ProteinModelPortaliP76116.
SMRiP76116. Positions 31-353.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260198. 4 interactions.
DIPiDIP-28079N.
IntActiP76116. 4 interactions.
STRINGi511145.b1452.

Proteomic databases

EPDiP76116.
PaxDbiP76116.
PRIDEiP76116.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74534; AAC74534; b1452.
BAE76445; BAE76445; BAE76445.
GeneIDi946006.
KEGGiecj:JW1447.
eco:b1452.
PATRICi32118196. VBIEscCol129921_1518.

Organism-specific databases

EchoBASEiEB3537.
EcoGeneiEG13775. yncE.

Phylogenomic databases

eggNOGiENOG4108NS2. Bacteria.
COG3391. LUCA.
HOGENOMiHOG000120631.
InParanoidiP76116.
OMAiQDDGKEH.
OrthoDBiEOG6VXF6Q.
PhylomeDBiP76116.

Enzyme and pathway databases

BioCyciEcoCyc:G6763-MONOMER.
ECOL316407:JW1447-MONOMER.

Miscellaneous databases

PROiP76116.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR011048. Haem_d1.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
SUPFAMiSSF51004. SSF51004. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. "Global iron-dependent gene regulation in Escherichia coli. A new mechanism for iron homeostasis."
    McHugh J.P., Rodriguez-Quinones F., Abdul-Tehrani H., Svistunenko D.A., Poole R.K., Cooper C.E., Andrews S.C.
    J. Biol. Chem. 278:29478-29486(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.
  4. "Defining the role of the Escherichia coli chaperone SecB using comparative proteomics."
    Baars L., Ytterberg A.J., Drew D., Wagner S., Thilo C., van Wijk K.J., de Gier J.W.
    J. Biol. Chem. 281:10024-10034(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY, SUBSTRATE FOR SECB.
    Strain: K12 / MC4100.
  5. "Overproduction, purification and preliminary X-ray diffraction analysis of YncE, an iron-regulated Sec-dependent periplasmic protein from Escherichia coli."
    Baba-Dikwa A., Thompson D., Spencer N.J., Andrews S.C., Watson K.A.
    Acta Crystallogr. F 64:966-969(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PRELIMINARY CRYSTALLIZATION, SUBUNIT.

Entry informationi

Entry nameiYNCE_ECOLI
AccessioniPrimary (citable) accession number: P76116
Secondary accession number(s): Q2MBB1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2002
Last sequence update: February 1, 1997
Last modified: May 11, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Preliminary crystallization indicates the presence of a single beta-propeller domain that contains 7 4-stranded beta-sheets.

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.