P76093 (YNBD_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YnbD

Gene names

Name:	ynbD
Ordered Locus Names:	b1411, JW1408

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	430 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the protein-tyrosine phosphatase family.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	peptidyl-tyrosine dephosphorylation Inferred from electronic annotation. Source: GOC
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	protein tyrosine phosphatase activity Inferred from electronic annotation. Source: InterPro protein tyrosine/serine/threonine phosphatase activity Inferred from Biological aspect of Ancestor. Source: RefGenome
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 430	430	Uncharacterized protein YnbD		PRO_0000094929
Regions
	Transmembrane	2 – 22	21	Helical; Potential
	Transmembrane	46 – 66	21	Helical; Potential
	Transmembrane	85 – 105	21	Helical; Potential
	Transmembrane	175 – 195	21	Helical; Potential
	Transmembrane	209 – 229	21	Helical; Potential
	Transmembrane	230 – 250	21	Helical; Potential
	Transmembrane	372 – 392	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P76093 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 7707978DD3F05EB8	FASTA	430	49,563
	10 20 30 40 50 60 MLQGAGWLLL LAPFFFFTYG SLNQFTAVQD LNSHDIPSQV FGWETAIPFL PWTIVPYWSL 70 80 90 100 110 120 DLLYGFSLFV CSTTFEQRRL VHRLILATVM ACCGFLLYPL KFSFIRPEVS GVTGWLFSQL 130 140 150 160 170 180 ELFDLPYNQS PSLHIILCWL LWRHFRQHLA ERWRKVCGGW FLLIAISTLT TWQHHFIDVI 190 200 210 220 230 240 TGLAVGMLID WMVPVDRRWN YQKPDQRRIK IALPYVVGAG SCIVLMELMM MIQLWWSVWL 250 260 270 280 290 300 CWPVLSLLII GRGYGGLGAI TTGKDSQGKL PPAVYWLTLP CRIGMWLSMR WFCRRLEPVS 310 320 330 340 350 360 KMTAGVYLGA FPRHIPAQNA VLDVTFEFPR GRATKDRLYF CVPMLDLVVP EEGELRQAVA 370 380 390 400 410 420 MLETLREEQG SVLVHCALGL SRSALVVAAW LLCYGHCKTV NEAISYIRAR RPQIVLTDEH 430 KAMLRLWENR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[3]	"Nucleotide sequence of the replication terminus region of Escherichia coli." Kitakawa M., Kasai H., Baba T., Honjo A., Isono K. Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 90-430. Strain: K12.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00096 Genomic DNA. Translation: AAC74493.1. AP009048 Genomic DNA. Translation: BAE76432.1. D85081 Genomic DNA. Translation: BAA25407.1.
PIR	F64892.
RefSeq	NP_415929.1. NC_000913.2. YP_489678.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P76093.
SMR	P76093. Positions 299-414.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-12745N.
IntAct	P76093. 2 interactions.
MINT	MINT-1248050.
STRING	511145.b1411.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC74493; AAC74493; b1411. BAE76432; BAE76432; BAE76432.
GeneID	12934030. 945985.
KEGG	ecj:Y75_p1387. eco:b1411.
PATRIC	32118108. VBIEscCol129921_1474.
Organism-specific databases
EchoBASE	EB3514.
EcoGene	EG13751. ynbD.
Phylogenomic databases
eggNOG	COG0671.
HOGENOM	HOG000259044.
OMA	KEDHKAM.
ProtClustDB	CLSK880081.
Enzyme and pathway databases
BioCyc	EcoCyc:G6730-MONOMER. ECOL316407:JW1408-MONOMER.
Gene expression databases
Genevestigator	P76093.
Family and domain databases
InterPro	IPR000340. Dual-sp_phosphatase_cat-dom. IPR020422. Dual-sp_phosphatase_subgr_cat. IPR024950. DUSP. IPR000326. P_Acid_Pase_2/haloperoxidase. IPR000387. Tyr/Dual-sp_Pase. IPR016130. Tyr_Pase_AS. [Graphical view]
PANTHER	PTHR10159. PTHR10159. 1 hit.
Pfam	PF00782. DSPc. 1 hit. PF01569. PAP2. 1 hit. [Graphical view]
SMART	SM00195. DSPc. 1 hit. [Graphical view]
PROSITE	PS00383. TYR_PHOSPHATASE_1. 1 hit. PS50056. TYR_PHOSPHATASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YNBD_ECOLI

Accession

Primary (citable) accession number: P76093
Secondary accession number(s): Q2MBC4

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	May 1, 2013
This is version 96 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program