P76027 (OPPD_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Oligopeptide transport ATP-binding protein OppD

Gene names

Name:	oppD
Ordered Locus Names:	b1246, JW1238

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	337 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system.
Subcellular location	Cell inner membrane; Peripheral membrane protein.
Sequence similarities	Belongs to the ABC transporter superfamily. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Peptide transport Protein transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC protein transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro peptidoglycan peptide transporter activity Inferred from genetic interaction PubMed 3301822. Source: EcoCyc
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 337	337	Oligopeptide transport ATP-binding protein OppD		PRO_0000092658
Regions
	Domain	20 – 269	250	ABC transporter
	Nucleotide binding	56 – 63	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	P76027 [UniParc]. Last modified October 11, 2004. Version 2. Checksum: B64BAA2C5794F359	FASTA	337	37,188
	10 20 30 40 50 60 MSVIETATVP LAQQQADALL NVKDLRVTFS TPDGDVTAVN DLNFSLRAGE TLGIVGESGS 70 80 90 100 110 120 GKSQTAFALM GLLAANGRIG GSATFNGREI LNLPEHELNK LRAEQISMIF QDPMTSLNPY 130 140 150 160 170 180 MRVGEQLMEV LMLHKNMSKA EAFEESVRML DAVKMPEARK RMKMYPHEFS GGMRQRVMIA 190 200 210 220 230 240 MALLCRPKLL IADEPTTALD VTVQAQIMTL LNELKREFNT AIIMITHDLV VVAGICDKVL 250 260 270 280 290 300 VMYAGRTMEY GNARDVFYQP VHPYSIGLLN AVPRLDAEGE TMLTIPGNPP NLLRLPKGCP 310 320 330 FQPRCPHAME ICSSAPPLEE FTPGRLRACF KPVEELL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map." Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K. , Nakade S., Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y., Wada C., Yamamoto Y., Horiuchi T. DNA Res. 3:363-377(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Escherichia coli K-12: a cooperatively developed annotation snapshot -- 2005." Riley M., Abe T., Arnaud M.B., Berlyn M.K.B., Blattner F.R., Chaudhuri R.R., Glasner J.D., Horiuchi T., Keseler I.M., Kosuge T., Mori H., Perna N.T., Plunkett G. III, Rudd K.E., Serres M.H., Thomas G.H., Thomson N.R., Wishart D., Wanner B.L. Nucleic Acids Res. 34:1-9(2006) [PubMed] [Europe PMC] [Abstract] Cited for: SEQUENCE REVISION TO 2.
[4]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00096 Genomic DNA. Translation: AAT48129.1. AP009048 Genomic DNA. Translation: BAA14778.1.
PIR	A64872.
RefSeq	YP_025300.1. NC_000913.2. YP_489514.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P76027.
SMR	P76027. Positions 17-259.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-10408N.
IntAct	P76027. 3 interactions.
MINT	MINT-1300671.
STRING	511145.b1246.
Proteomic databases
PaxDb	P76027.
PRIDE	P76027.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAT48129; AAT48129; b1246. BAA14778; BAA14778; BAA14778.
GeneID	12930500. 945802.
KEGG	ecj:Y75_p1220. eco:b1246.
PATRIC	32117752. VBIEscCol129921_1296.
Organism-specific databases
EchoBASE	EB0671.
EcoGene	EG10677. oppD.
Phylogenomic databases
eggNOG	COG0444.
KO	K15583.
OMA	ICNSAPP.
ProtClustDB	PRK09473.
Enzyme and pathway databases
BioCyc	EcoCyc:OPPD-MONOMER. ECOL316407:JW1238-MONOMER.
Gene expression databases
Genevestigator	P76027.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR010066. Oligo_ATP-bd_C. IPR013563. Oligopep_ABC_C. [Graphical view]
Pfam	PF00005. ABC_tran. 1 hit. PF08352. oligo_HPY. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
TIGRFAMs	TIGR01727. oligo_HPY. 1 hit.
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

OPPD_ECOLI

Accession

Primary (citable) accession number: P76027
Secondary accession number(s): P77382

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	October 11, 2004
Last modified:	May 1, 2013
This is version 107 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program