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Protein

Inhibitor of g-type lysozyme

Gene

pliG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium.1 Publication

GO - Molecular functioni

  • lysozyme inhibitor activity Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G6615-MONOMER.
ECOL316407:JW1167-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inhibitor of g-type lysozyme
Gene namesi
Name:pliG
Synonyms:ycgK
Ordered Locus Names:b1178, JW1167
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13892. pliG.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
  • periplasmic space Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence analysisAdd
BLAST
Chaini23 – 133111Inhibitor of g-type lysozymePRO_0000013828Add
BLAST

Proteomic databases

EPDiP76002.
PaxDbiP76002.
PRIDEiP76002.

2D gel databases

SWISS-2DPAGEP76002.

Interactioni

Protein-protein interaction databases

BioGridi4260099. 13 interactions.
IntActiP76002. 1 interaction.
STRINGi511145.b1178.

Structurei

Secondary structure

1
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi26 – 283Combined sources
Beta strandi36 – 4510Combined sources
Beta strandi50 – 567Combined sources
Beta strandi61 – 677Combined sources
Beta strandi72 – 765Combined sources
Beta strandi102 – 11211Combined sources
Helixi115 – 1195Combined sources
Beta strandi123 – 13311Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4DXZX-ray1.25A23-133[»]
4DY3X-ray1.80A/B23-133[»]
4G9SX-ray0.95B23-133[»]
ProteinModelPortaliP76002.
SMRiP76002. Positions 23-133.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG41066UD. Bacteria.
ENOG41129QS. LUCA.
HOGENOMiHOG000269686.
OMAiYNINIQI.
OrthoDBiEOG6DVJSJ.

Family and domain databases

InterProiIPR007280. Peptidase_C_arc/bac.
[Graphical view]
PfamiPF04151. PPC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P76002-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIKSIRKAV LLLALLTSTS FAAGKNVNVE FRKGHSSAQY SGEIKGYDYD
60 70 80 90 100
TYTFYAKKGQ KVHVSISNEG ADTYLFGPGI DDSVDLSRYS PELDSHGQYS
110 120 130
LPASGKYELR VLQTRNDARK NKTKKYNVDI QIK
Length:133
Mass (Da):14,906
Last modified:February 1, 1997 - v1
Checksum:i54997548219541F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74262.1.
AP009048 Genomic DNA. Translation: BAA36012.1.
PIRiG64863.
RefSeqiNP_415696.1. NC_000913.3.
WP_000695215.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74262; AAC74262; b1178.
BAA36012; BAA36012; BAA36012.
GeneIDi946963.
KEGGiecj:JW1167.
eco:b1178.
PATRICi32117600. VBIEscCol129921_1222.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74262.1.
AP009048 Genomic DNA. Translation: BAA36012.1.
PIRiG64863.
RefSeqiNP_415696.1. NC_000913.3.
WP_000695215.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4DXZX-ray1.25A23-133[»]
4DY3X-ray1.80A/B23-133[»]
4G9SX-ray0.95B23-133[»]
ProteinModelPortaliP76002.
SMRiP76002. Positions 23-133.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260099. 13 interactions.
IntActiP76002. 1 interaction.
STRINGi511145.b1178.

2D gel databases

SWISS-2DPAGEP76002.

Proteomic databases

EPDiP76002.
PaxDbiP76002.
PRIDEiP76002.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74262; AAC74262; b1178.
BAA36012; BAA36012; BAA36012.
GeneIDi946963.
KEGGiecj:JW1167.
eco:b1178.
PATRICi32117600. VBIEscCol129921_1222.

Organism-specific databases

EchoBASEiEB3651.
EcoGeneiEG13892. pliG.

Phylogenomic databases

eggNOGiENOG41066UD. Bacteria.
ENOG41129QS. LUCA.
HOGENOMiHOG000269686.
OMAiYNINIQI.
OrthoDBiEOG6DVJSJ.

Enzyme and pathway databases

BioCyciEcoCyc:G6615-MONOMER.
ECOL316407:JW1167-MONOMER.

Miscellaneous databases

PROiP76002.

Family and domain databases

InterProiIPR007280. Peptidase_C_arc/bac.
[Graphical view]
PfamiPF04151. PPC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. Cited for: FUNCTION, SUBCELLULAR LOCATION, IDENTIFICATION BY MASS SPECTROMETRY.
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiPLIG_ECOLI
AccessioniPrimary (citable) accession number: P76002
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: July 6, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.