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Protein

Inner membrane protein YmfA

Gene

ymfA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:G6579-MONOMER.
ECOL316407:JW5164-MONOMER.

Protein family/group databases

TCDBi9.B.122.1.1. the duf3592 or pf12158 (duf3592) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane protein YmfA
Gene namesi
Name:ymfA
Ordered Locus Names:b1122, JW5164
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13445. ymfA.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 66CytoplasmicSequence analysis
Transmembranei7 – 2721HelicalSequence analysisAdd
BLAST
Topological domaini28 – 11689PeriplasmicSequence analysisAdd
BLAST
Transmembranei117 – 13721HelicalSequence analysisAdd
BLAST
Topological domaini138 – 15316CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 153153Inner membrane protein YmfAPRO_0000168840Add
BLAST

Proteomic databases

PaxDbiP75962.

Interactioni

Protein-protein interaction databases

BioGridi4260091. 8 interactions.
STRINGi511145.b1122.

Structurei

3D structure databases

ProteinModelPortaliP75962.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000119107.
OMAiDSAMINT.
OrthoDBiEOG6V7BN5.

Family and domain databases

InterProiIPR021994. DUF3592.
[Graphical view]
PfamiPF12158. DUF3592. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P75962-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQDSKVFFR IFLGIGLVLI LISVVVFYNQ FTYSKDAIHT EGVIVDTVWH
60 70 80 90 100
SSHSHRTGKD GSWYPVVAFR PTPDYTLIFN SSIGSDFYED SEGDKVNVYY
110 120 130 140 150
SPGHPEKAEI NNPWVNFFKW GFIGIMGVIF IAVGLLISMP SSKKSRRKRK

SRP
Length:153
Mass (Da):17,416
Last modified:August 29, 2001 - v2
Checksum:iDFD1327C9505EB33
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74206.2.
AP009048 Genomic DNA. Translation: BAA35942.2.
PIRiG64856.
RefSeqiNP_415640.2. NC_000913.3.
WP_000076376.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74206; AAC74206; b1122.
BAA35942; BAA35942; BAA35942.
GeneIDi945684.
KEGGiecj:JW5164.
eco:b1122.
PATRICi32117491. VBIEscCol129921_1168.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74206.2.
AP009048 Genomic DNA. Translation: BAA35942.2.
PIRiG64856.
RefSeqiNP_415640.2. NC_000913.3.
WP_000076376.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP75962.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260091. 8 interactions.
STRINGi511145.b1122.

Protein family/group databases

TCDBi9.B.122.1.1. the duf3592 or pf12158 (duf3592) family.

Proteomic databases

PaxDbiP75962.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74206; AAC74206; b1122.
BAA35942; BAA35942; BAA35942.
GeneIDi945684.
KEGGiecj:JW5164.
eco:b1122.
PATRICi32117491. VBIEscCol129921_1168.

Organism-specific databases

EchoBASEiEB3219.
EcoGeneiEG13445. ymfA.

Phylogenomic databases

HOGENOMiHOG000119107.
OMAiDSAMINT.
OrthoDBiEOG6V7BN5.

Enzyme and pathway databases

BioCyciEcoCyc:G6579-MONOMER.
ECOL316407:JW5164-MONOMER.

Miscellaneous databases

PROiP75962.

Family and domain databases

InterProiIPR021994. DUF3592.
[Graphical view]
PfamiPF12158. DUF3592. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYMFA_ECOLI
AccessioniPrimary (citable) accession number: P75962
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: August 29, 2001
Last modified: January 20, 2016
This is version 100 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.