P75937 (FLGE_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Flagellar hook protein FlgE

Gene names

Name:	flgE
Synonyms:	fla FV, flaK
Ordered Locus Names:	b1076, JW1063

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	402 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Bacterial flagellum basal body By similarity.
Sequence similarities	Belongs to the flagella basal body rod proteins family.

Ontologies

Keywords
Cellular component	Bacterial flagellum
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ciliary or flagellar motility Inferred from electronic annotation. Source: InterPro
Cellular_component	bacterial-type flagellum basal body, rod Inferred from electronic annotation. Source: InterPro bacterial-type flagellum hook Inferred from mutant phenotype PubMed 338588PubMed 6374380. Source: EcoliWiki
Molecular_function	motor activity Inferred from electronic annotation. Source: InterPro structural molecule activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 402	401	Flagellar hook protein FlgE		PRO_0000180825

Sequences

	Sequence		Length	Mass (Da)
	P75937 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: E81FBF5FA99C3220	FASTA	402	42,045
	10 20 30 40 50 60 MAFSQAVSGL NAAATNLDVI GNNIANSATY GFKSGTASFA DMFAGSKVGL GVKVAGITQD 70 80 90 100 110 120 FTDGTTTNTG RGLDVAISQN GFFRLVDSNG SVFYSRNGQF KLDENRNLVN MQGLQLTGYP 130 140 150 160 170 180 ATGTPPTIQQ GANPTNISIP NTLMAAKTTT TASMQINLNS SDPLPTVTPF SASNADSYNK 190 200 210 220 230 240 KGSVTVFDSQ GNAHDMSVYF VKTGDNNWQV YTQDSSDPNS IAKTATTLEF NANGTLVDGA 250 260 270 280 290 300 MANNIATGAI NGAEPATFSL SFLNSMQQNT GANNIVATTQ NGYKPGDLVS YQINDDGTVV 310 320 330 340 350 360 GNYSNEQTQL LGQIVLANFA NNEGLASEGD NVWSATQSSG VALLGTAGTG NFGTLTNGAL 370 380 390 400 EASNVDLSKE LVNMIVAQRN YQSNAQTIKT QDQILNTLVN LR

References

[1]	"A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K., Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S., Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K. , Mori H., Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G., Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M., Horiuchi T. DNA Res. 3:137-155(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00096 Genomic DNA. Translation: AAC74160.1. AP009048 Genomic DNA. Translation: BAA35885.1.
PIR	A64851.
RefSeq	NP_415594.1. NC_000913.2. YP_489344.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P75937.
SMR	P75937. Positions 2-402.
ModBase	Search...
Protein-protein interaction databases
IntAct	P75937. 3 interactions.
STRING	511145.b1076.
Proteomic databases
PaxDb	P75937.
PRIDE	P75937.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC74160; AAC74160; b1076. BAA35885; BAA35885; BAA35885.
GeneID	12931080. 945636.
KEGG	ecj:Y75_p1046. eco:b1076.
PATRIC	32117393. VBIEscCol129921_1119.
Organism-specific databases
EchoBASE	EB4017.
EcoGene	EG14269. flgE.
Phylogenomic databases
eggNOG	COG1749.
HOGENOM	HOG000254240.
KO	K02390.
OMA	QSARIEE.
ProtClustDB	PRK05682.
Enzyme and pathway databases
BioCyc	EcoCyc:G361-MONOMER. ECOL316407:JW1063-MONOMER.
Gene expression databases
Genevestigator	P75937.
Family and domain databases
InterPro	IPR011491. Falgellar_basal_body_FlaE. IPR001444. Flag_bb_rod_N. IPR019776. Flagellar_basal_body_rod_CS. IPR020013. Flagellar_FlgE/F/G. IPR010930. Flg_bb/hook_C_dom. [Graphical view]
Pfam	PF07559. FlaE. 1 hit. PF00460. Flg_bb_rod. 1 hit. PF06429. Flg_bbr_C. 1 hit. [Graphical view]
TIGRFAMs	TIGR03506. FlgEFG_subfam. 1 hit.
PROSITE	PS00588. FLAGELLA_BB_ROD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FLGE_ECOLI

Accession

Primary (citable) accession number: P75937
Secondary accession number(s): Q9R7P1

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	January 23, 2007
Last modified:	May 1, 2013
This is version 90 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program