Reviewed, UniProtKB/Swiss-Prot P75937 (FLGE_ECOLI)

Names and origin

Protein names

Recommended name:
    Flagellar hook protein flgE

Gene names

Name:	flgE
Synonyms:	fla FV, flaK
Ordered Locus Names:	b1076, JW1063

Organism

Escherichia coli (strain K12) [Complete proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	402 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subcellular location	Bacterial flagellum basal bodyBy similarity.
Sequence similarities	Belongs to the flagella basal body rod proteins family.

Ontologies

Keywords
Cellular component	Bacterial flagellum
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ciliary or flagellar motility Inferred from electronic annotation. Source: InterPro
Cellular component	flagellin-based flagellum basal body, rod Inferred from electronic annotation. Source: InterPro
Molecular function	motor activity Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: IntAct structural molecule activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
nadE	P18843	1	EBI-1122032,EBI-548960

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 402	401	Flagellar hook protein flgE		PRO_0000180825

Sequences

	Sequence		Length	Mass (Da)
	P75937-1 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: E81FBF5FA99C3220	FASTA	402	42,045
	10 20 30 40 50 60 MAFSQAVSGL NAAATNLDVI GNNIANSATY GFKSGTASFA DMFAGSKVGL GVKVAGITQD 70 80 90 100 110 120 FTDGTTTNTG RGLDVAISQN GFFRLVDSNG SVFYSRNGQF KLDENRNLVN MQGLQLTGYP 130 140 150 160 170 180 ATGTPPTIQQ GANPTNISIP NTLMAAKTTT TASMQINLNS SDPLPTVTPF SASNADSYNK 190 200 210 220 230 240 KGSVTVFDSQ GNAHDMSVYF VKTGDNNWQV YTQDSSDPNS IAKTATTLEF NANGTLVDGA 250 260 270 280 290 300 MANNIATGAI NGAEPATFSL SFLNSMQQNT GANNIVATTQ NGYKPGDLVS YQINDDGTVV 310 320 330 340 350 360 GNYSNEQTQL LGQIVLANFA NNEGLASEGD NVWSATQSSG VALLGTAGTG NFGTLTNGAL 370 380 390 400 EASNVDLSKE LVNMIVAQRN YQSNAQTIKT QDQILNTLVN LR

References

[1]	"A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K., Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S., Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K. , Mori H., Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G., Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M., Horiuchi T. DNA Res. 3:137-155(1996) [PubMed: 8905232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U00096 Genomic DNA. Translation: AAC74160.1. AP009048 Genomic DNA. Translation: BAA35885.1.
PIR	A64851.
RefSeq	AP_001702.1. NP_415594.1.
3D structure databases
SMR	P75937. Positions 72-363.
ModBase	Search...
Protein-protein interaction databases
IntAct	P75937.
Genome annotation databases
GeneID	945636.
GenomeReviews	Gene locus b1076 in contig U00096_GR. Gene locus JW1063 in contig AP009048_GR.
KEGG	ecj:JW1063. eco:b1076.
Organism-specific databases
EchoBASE	EB4017.
EcoGene	EG14269. flgE.
CMR	Search...
Phylogenomic databases
HOGENOM	P75937.
Enzyme and pathway databases
BioCyc	EcoCyc:G361-MON.
Family and domain databases
InterPro	IPR010930. DUF1078_C. IPR011491. FlaE. IPR001444. Flag_bb_rod. [Graphical view]
Pfam	PF06429. DUF1078. 1 hit. PF07559. FlaE. 1 hit. PF00460. Flg_bb_rod. 1 hit. [Graphical view]
PROSITE	PS00588. FLAGELLA_BB_ROD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FLGE_ECOLI

Accession

Primary (citable) accession number: P75937
Secondary accession number(s): Q9R7P1

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	January 23, 2007
Last modified:	November 25, 2008
This is version 54 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)