P75936 (FLGD_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Basal-body rod modification protein flgD

Gene names

Name:	flgD
Synonyms:	fla FIV, flaV
Ordered Locus Names:	b1075, JW1062

Organism

Escherichia coli (strain K12)

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	231 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for flagellar hook formation. May act as a scaffolding protein.
Sequence similarities	Belongs to the flgD family.

Ontologies

Keywords
Biological process	Bacterial flagellum biogenesis
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	flagellum organization Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 231	231	Basal-body rod modification protein flgD		PRO_0000180812

Sequences

	Sequence		Length	Mass (Da)
	P75936 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 0043419C80F3A4C6	FASTA	231	23,575
	10 20 30 40 50 60 MSIAVTTTDP TNTGVSTTSS SSLTGSNAAD LQSSFLTLLV AQLKNQDPTN PMENNELTSQ 70 80 90 100 110 120 LAQISTVSGI EKLNTTLGSI SGQIDNSQSL QASNLIGHGV MIPGTTVLAG TGSEEGAVTT 130 140 150 160 170 180 TTPFGVELQQ AADKVTATIT DKNGAVVRTI DIGELTAGVH SFTWDGTLTD GSTAPNGSYN 190 200 210 220 230 VAISASNGGT QLVAQPLQFA LVQGVIRGNS GNTLDLGTYG TTTLDEVRQI I

References

[1]	"A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K., Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S., Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K. , Mori H., Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G., Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M., Horiuchi T. DNA Res. 3:137-155(1996) [PubMed: 8905232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00096 Genomic DNA. Translation: AAC74159.1. AP009048 Genomic DNA. Translation: BAA35883.1.
PIR	H64850.
RefSeq	NP_415593.1. NC_000913.2.
3D structure databases
ProteinModelPortal	P75936.
SMR	P75936. Positions 92-230.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-9632N.
IntAct	P75936. 3 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000004189; EBESCP00000004189; EBESCG00000003419. EBESCT00000016456; EBESCP00000015747; EBESCG00000015516.
GeneID	945813.
GenomeReviews	Gene locus JW1062 in contig AP009048_GR. Gene locus b1075 in contig U00096_GR.
KEGG	ecj:JW1062. eco:b1075.
PATRIC	32117391. VBIEscCol129921_1118.
Organism-specific databases
EchoBASE	EB4016.
EcoGene	EG14268. flgD.
Phylogenomic databases
eggNOG	COG1843.
GeneTree	EBGT00050000009302.
HOGENOM	HBG691812.
OMA	LAISGQI.
PhylomeDB	P75936.
ProtClustDB	PRK06655.
Enzyme and pathway databases
BioCyc	EcoCyc:G360-MONOMER.
Gene expression databases
Genevestigator	P75936.
Family and domain databases
InterPro	IPR005648. FlgD. [Graphical view]
KO	K02389.
Pfam	PF03963. FlgD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FLGD_ECOLI

Accession

Primary (citable) accession number: P75936

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 81 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program