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Protein

Basal-body rod modification protein FlgD

Gene

flgD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Required for flagellar hook formation. May act as a scaffolding protein.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Bacterial flagellum biogenesis

Enzyme and pathway databases

BioCyciEcoCyc:G360-MONOMER.
ECOL316407:JW1062-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Basal-body rod modification protein FlgD
Gene namesi
Name:flgD
Synonyms:fla FIV, flaV
Ordered Locus Names:b1075, JW1062
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14268. flgD.

Subcellular locationi

GO - Cellular componenti

  • bacterial-type flagellum hook Source: GO_Central
  • cytosol Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 231231Basal-body rod modification protein FlgDPRO_0000180812Add
BLAST

Proteomic databases

PaxDbiP75936.

Interactioni

Protein-protein interaction databases

BioGridi4263351. 15 interactions.
DIPiDIP-9632N.
IntActiP75936. 3 interactions.
STRINGi511145.b1075.

Structurei

3D structure databases

ProteinModelPortaliP75936.
SMRiP75936. Positions 88-230.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FlgD family.Curated

Phylogenomic databases

eggNOGiENOG4105W00. Bacteria.
COG1843. LUCA.
HOGENOMiHOG000265647.
InParanoidiP75936.
KOiK02389.
OMAiYTWNGKD.
OrthoDBiEOG6BKJ7S.
PhylomeDBiP75936.

Family and domain databases

InterProiIPR005648. FlgD.
IPR025965. FlgD_Ig.
IPR025963. FLgD_Tudor.
[Graphical view]
PfamiPF03963. FlgD. 1 hit.
PF13860. FlgD_ig. 1 hit.
PF13861. FLgD_tudor. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P75936-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIAVTTTDP TNTGVSTTSS SSLTGSNAAD LQSSFLTLLV AQLKNQDPTN
60 70 80 90 100
PMENNELTSQ LAQISTVSGI EKLNTTLGSI SGQIDNSQSL QASNLIGHGV
110 120 130 140 150
MIPGTTVLAG TGSEEGAVTT TTPFGVELQQ AADKVTATIT DKNGAVVRTI
160 170 180 190 200
DIGELTAGVH SFTWDGTLTD GSTAPNGSYN VAISASNGGT QLVAQPLQFA
210 220 230
LVQGVIRGNS GNTLDLGTYG TTTLDEVRQI I
Length:231
Mass (Da):23,575
Last modified:February 1, 1997 - v1
Checksum:i0043419C80F3A4C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74159.1.
AP009048 Genomic DNA. Translation: BAA35883.1.
PIRiH64850.
RefSeqiNP_415593.1. NC_000913.3.
WP_000020486.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74159; AAC74159; b1075.
BAA35883; BAA35883; BAA35883.
GeneIDi945813.
KEGGiecj:JW1062.
eco:b1075.
PATRICi32117391. VBIEscCol129921_1118.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74159.1.
AP009048 Genomic DNA. Translation: BAA35883.1.
PIRiH64850.
RefSeqiNP_415593.1. NC_000913.3.
WP_000020486.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP75936.
SMRiP75936. Positions 88-230.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263351. 15 interactions.
DIPiDIP-9632N.
IntActiP75936. 3 interactions.
STRINGi511145.b1075.

Proteomic databases

PaxDbiP75936.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74159; AAC74159; b1075.
BAA35883; BAA35883; BAA35883.
GeneIDi945813.
KEGGiecj:JW1062.
eco:b1075.
PATRICi32117391. VBIEscCol129921_1118.

Organism-specific databases

EchoBASEiEB4016.
EcoGeneiEG14268. flgD.

Phylogenomic databases

eggNOGiENOG4105W00. Bacteria.
COG1843. LUCA.
HOGENOMiHOG000265647.
InParanoidiP75936.
KOiK02389.
OMAiYTWNGKD.
OrthoDBiEOG6BKJ7S.
PhylomeDBiP75936.

Enzyme and pathway databases

BioCyciEcoCyc:G360-MONOMER.
ECOL316407:JW1062-MONOMER.

Miscellaneous databases

PROiP75936.

Family and domain databases

InterProiIPR005648. FlgD.
IPR025965. FlgD_Ig.
IPR025963. FLgD_Tudor.
[Graphical view]
PfamiPF03963. FlgD. 1 hit.
PF13860. FlgD_ig. 1 hit.
PF13861. FLgD_tudor. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiFLGD_ECOLI
AccessioniPrimary (citable) accession number: P75936
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: January 20, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.