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Protein

Flagella basal body P-ring formation protein FlgA

Gene

flgA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.

GO - Biological processi

  • bacterial-type flagellum-dependent cell motility Source: EcoCyc
  • bacterial-type flagellum organization Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Bacterial flagellum biogenesis

Enzyme and pathway databases

BioCyciEcoCyc:G357-MONOMER.
ECOL316407:JW1059-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagella basal body P-ring formation protein FlgA
Gene namesi
Name:flgA
Ordered Locus Names:b1072, JW1059
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG20263. flgA.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Or 26Sequence analysisAdd
BLAST
Chaini22 – 219198Flagella basal body P-ring formation protein FlgAPRO_0000009341Add
BLAST

Proteomic databases

EPDiP75933.
PaxDbiP75933.
PRIDEiP75933.

Interactioni

Protein-protein interaction databases

BioGridi4260070. 182 interactions.
IntActiP75933. 2 interactions.
STRINGi511145.b1072.

Structurei

3D structure databases

ProteinModelPortaliP75933.
SMRiP75933. Positions 23-219.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FlgA family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105CKS. Bacteria.
COG1261. LUCA.
HOGENOMiHOG000119039.
InParanoidiP75933.
KOiK02386.
OMAiFFQQQYP.
OrthoDBiEOG6VQPS9.

Family and domain databases

InterProiIPR017585. Flag_basal_body_FlgA_C.
IPR013974. SAF.
[Graphical view]
PfamiPF13144. ChapFlgA. 1 hit.
[Graphical view]
SMARTiSM00858. SAF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03170. flgA_cterm. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P75933-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLIIKRSVAI IAILFSPLST ASNLTSQLHN FFSAQLAGVS DEVRVSIRTA
60 70 80 90 100
PNLLPPCEQP LLSMSNNSRL WGNVNVLARC GNDKRYLQVN VQATGNYVVA
110 120 130 140 150
AMPIARGGKL EAGNVKLKRG RLDTLPPRTV LDINQLVDAI SLRDLSPDQP
160 170 180 190 200
IQLTQFRQAW RVKAGQRVNV IASGDGFSAN AEGQALNNAA VAQNARVRMV
210
SGQVVSGVVD ADGNILINL
Length:219
Mass (Da):23,519
Last modified:February 1, 1997 - v1
Checksum:i69D8E6252E9ED73A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74156.1.
AP009048 Genomic DNA. Translation: BAA35880.1.
PIRiE64850.
RefSeqiNP_415590.1. NC_000913.3.
WP_000905458.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74156; AAC74156; b1072.
BAA35880; BAA35880; BAA35880.
GeneIDi946300.
KEGGiecj:JW1059.
eco:b1072.
PATRICi32117383. VBIEscCol129921_1114.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74156.1.
AP009048 Genomic DNA. Translation: BAA35880.1.
PIRiE64850.
RefSeqiNP_415590.1. NC_000913.3.
WP_000905458.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP75933.
SMRiP75933. Positions 23-219.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260070. 182 interactions.
IntActiP75933. 2 interactions.
STRINGi511145.b1072.

Proteomic databases

EPDiP75933.
PaxDbiP75933.
PRIDEiP75933.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74156; AAC74156; b1072.
BAA35880; BAA35880; BAA35880.
GeneIDi946300.
KEGGiecj:JW1059.
eco:b1072.
PATRICi32117383. VBIEscCol129921_1114.

Organism-specific databases

EchoBASEiEB4160.
EcoGeneiEG20263. flgA.

Phylogenomic databases

eggNOGiENOG4105CKS. Bacteria.
COG1261. LUCA.
HOGENOMiHOG000119039.
InParanoidiP75933.
KOiK02386.
OMAiFFQQQYP.
OrthoDBiEOG6VQPS9.

Enzyme and pathway databases

BioCyciEcoCyc:G357-MONOMER.
ECOL316407:JW1059-MONOMER.

Miscellaneous databases

PROiP75933.

Family and domain databases

InterProiIPR017585. Flag_basal_body_FlgA_C.
IPR013974. SAF.
[Graphical view]
PfamiPF13144. ChapFlgA. 1 hit.
[Graphical view]
SMARTiSM00858. SAF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03170. flgA_cterm. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiFLGA_ECOLI
AccessioniPrimary (citable) accession number: P75933
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: March 16, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.