P75931 (YCEM_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative oxidoreductase YceM
EC=1.-.-.-

Gene names

Name:	yceM
Synonyms:	mviM
Ordered Locus Names:	b1068, JW1055

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	307 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the Gfo/Idh/MocA family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 307

307

Putative oxidoreductase YceM

PRO_0000096654

Secondary structure

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307

Helix Strand Turn

Details...

Beta strand

4 – 9

6

Helix

14 – 17

4

Helix

19 – 24

6

Beta strand

27 – 35

9

Helix

42 – 49

8

Helix

57 – 61

5

Beta strand

65 – 69

5

Helix

73 – 75

3

Helix

76 – 85

10

Beta strand

89 – 96

8

Helix

100 – 112

13

Beta strand

117 – 120

4

Helix

122 – 125

4

Helix

127 – 132

6

Turn

133 – 135

3

Helix

136 – 138

3

Beta strand

141 – 146

6

Helix

157 – 163

7

Helix

165 – 175

11

Turn

176 – 178

3

Beta strand

182 – 189

8

Beta strand

195 – 204

10

Beta strand

207 – 218

12

Beta strand

222 – 228

7

Beta strand

231 – 236

6

Turn

237 – 239

3

Beta strand

240 – 247

8

Beta strand

249 – 251

3

Helix

260 – 263

4

Helix

266 – 279

14

Helix

287 – 290

4

Helix

292 – 304

13

Sequences

	Sequence		Length	Mass (Da)
	P75931 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: E8BB622AE0C5C92C	FASTA	307	33,682
	10 20 30 40 50 60 MKKLRIGVVG LGGIAQKAWL PVLAAASDWT LQGAWSPTRA KALPICESWR IPYADSLSSL 70 80 90 100 110 120 AASCDAVFVH SSTASHFDVV STLLNAGVHV CVDKPLAENL RDAERLVELA ARKKLTLMVG 130 140 150 160 170 180 FNRRFAPLYG ELKTQLATAA SLRMDKHRSN SVGPHDLYFT LLDDYLHVVD TALWLSGGKA 190 200 210 220 230 240 SLDGGTLLTN DAGEMLFAEH HFSAGPLQIT TCMHRRAGSQ RETVQAVTDG ALIDITDMRE 250 260 270 280 290 300 WREERGQGVV HKPIPGWQST LEQRGFVGCA RHFIECVQNQ TVPQTAGEQA VLAQRIVDKI WRDAMSE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K., Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S., Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K. , Mori H., Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G., Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M., Horiuchi T. DNA Res. 3:137-155(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Crystal structure of a putative oxidoreductase (virulence factor MviM homolog)." Rajashankar K.R., Solorzano V., Kniewel R., Lima C.D. Submitted (JUN-2004) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.70 ANGSTROMS) OF 2-307.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U00096 Genomic DNA. Translation: AAC74152.1.
AP009048 Genomic DNA. Translation: BAA35876.1.

PIR

A64850.

RefSeq

NP_415586.1. NC_000913.2.
YP_489336.1. NC_007779.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1TLT	X-ray	2.70	A/B	2-307	[»]

ProteinModelPortal

P75931.

SMR

P75931. Positions 3-307.

ModBase

Search...

Protein-protein interaction databases

IntAct

P75931. 3 interactions.

STRING

511145.b1068.

Proteomic databases

PaxDb

P75931.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAC74152; AAC74152; b1068.
BAA35876; BAA35876; BAA35876.

GeneID

12930409.
945204.

KEGG

ecj:Y75_p1038.
eco:b1068.

PATRIC

32117375. VBIEscCol129921_1110.

Organism-specific databases

EchoBASE

EB3638.

EcoGene

EG13879. yceM.

Phylogenomic databases

eggNOG

COG0673.

HOGENOM

HOG000039102.

KO

K03810.

OMA

QCDAVFV.

ProtClustDB

CLSK879949.

Enzyme and pathway databases

BioCyc

EcoCyc:G6560-MONOMER.
ECOL316407:JW1055-MONOMER.

Gene expression databases

Genevestigator

P75931.

Family and domain databases

Gene3D

3.40.50.720. 1 hit.

InterPro

IPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
IPR004104. OxRdtase_C.
[Graphical view]

Pfam

PF01408. GFO_IDH_MocA. 1 hit.
PF02894. GFO_IDH_MocA_C. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

P75931.

Entry information

Entry name

YCEM_ECOLI

Accession

Primary (citable) accession number: P75931

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	May 1, 2013
This is version 90 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program