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Protein

Cytochrome b561 homolog 2

Gene

yceJ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

heme bBy similarityNote: Binds 2 heme B (iron-protoporphyrin IX) groups per molecule.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi18 – 181Iron (heme axial ligand)Sequence analysis
Metal bindingi52 – 521Iron (heme axial ligand)Sequence analysis
Metal bindingi159 – 1591Iron (heme axial ligand)Sequence analysis
Metal bindingi166 – 1661Iron (heme axial ligand)Sequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6554-MONOMER.
ECOL316407:JW1044-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome b561 homolog 2
Gene namesi
Name:yceJ
Ordered Locus Names:b1057, JW1044
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12659. yceJ.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1515PeriplasmicSequence analysisAdd
BLAST
Transmembranei16 – 3621HelicalSequence analysisAdd
BLAST
Topological domaini37 – 9155CytoplasmicSequence analysisAdd
BLAST
Transmembranei92 – 11221HelicalSequence analysisAdd
BLAST
Topological domaini113 – 14331PeriplasmicSequence analysisAdd
BLAST
Transmembranei144 – 16421HelicalSequence analysisAdd
BLAST
Topological domaini165 – 18824CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 188188Cytochrome b561 homolog 2PRO_0000199975Add
BLAST

Proteomic databases

PaxDbiP75925.

Interactioni

Protein-protein interaction databases

BioGridi4261751. 6 interactions.
STRINGi511145.b1057.

Structurei

3D structure databases

ProteinModelPortaliP75925.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome b561 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DS1. Bacteria.
COG3038. LUCA.
HOGENOMiHOG000110385.
InParanoidiP75925.
OMAiWYKTAPH.
PhylomeDBiP75925.

Family and domain databases

InterProiIPR011577. Cyt_b561_bac/Ni-Hgenase.
IPR016174. Di-haem_cyt_TM.
[Graphical view]
PfamiPF01292. Ni_hydr_CYTB. 1 hit.
[Graphical view]
SUPFAMiSSF81342. SSF81342. 1 hit.

Sequencei

Sequence statusi: Complete.

P75925-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFTNTPERY GVISAAFHWL SAIIVYGMFA LGLWMVTLSY YDGWYHKAPE
60 70 80 90 100
LHKSIGILLM MGLVIRVLWR VISPPPGPLP SYSPMTRLAA RAGHLALYLL
110 120 130 140 150
LFAIGISGYL ISTADGKPIS VFGWFDVPAT LADAGAQADF AGALHFWLAW
160 170 180
SVVVLSVMHG FMALKHHFID KDDTLKRMLG KSSSDYGV
Length:188
Mass (Da):20,736
Last modified:February 1, 1997 - v1
Checksum:i1F7B8E575E2E3307
GO

Sequence cautioni

The sequence BAA06517 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74141.1.
AP009048 Genomic DNA. Translation: BAA35855.1.
D31709 Genomic DNA. Translation: BAA06517.1. Different initiation.
PIRiF64848.
RefSeqiNP_415575.1. NC_000913.3.
WP_000011114.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74141; AAC74141; b1057.
BAA35855; BAA35855; BAA35855.
GeneIDi945628.
KEGGiecj:JW1044.
eco:b1057.
PATRICi32117351. VBIEscCol129921_1098.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74141.1.
AP009048 Genomic DNA. Translation: BAA35855.1.
D31709 Genomic DNA. Translation: BAA06517.1. Different initiation.
PIRiF64848.
RefSeqiNP_415575.1. NC_000913.3.
WP_000011114.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP75925.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261751. 6 interactions.
STRINGi511145.b1057.

Proteomic databases

PaxDbiP75925.

Protocols and materials databases

DNASUi945628.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74141; AAC74141; b1057.
BAA35855; BAA35855; BAA35855.
GeneIDi945628.
KEGGiecj:JW1044.
eco:b1057.
PATRICi32117351. VBIEscCol129921_1098.

Organism-specific databases

EchoBASEiEB2526.
EcoGeneiEG12659. yceJ.

Phylogenomic databases

eggNOGiENOG4105DS1. Bacteria.
COG3038. LUCA.
HOGENOMiHOG000110385.
InParanoidiP75925.
OMAiWYKTAPH.
PhylomeDBiP75925.

Enzyme and pathway databases

BioCyciEcoCyc:G6554-MONOMER.
ECOL316407:JW1044-MONOMER.

Miscellaneous databases

PROiP75925.

Family and domain databases

InterProiIPR011577. Cyt_b561_bac/Ni-Hgenase.
IPR016174. Di-haem_cyt_TM.
[Graphical view]
PfamiPF01292. Ni_hydr_CYTB. 1 hit.
[Graphical view]
SUPFAMiSSF81342. SSF81342. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiC56I_ECOLI
AccessioniPrimary (citable) accession number: P75925
Secondary accession number(s): Q47145
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: February 1, 1997
Last modified: September 7, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.