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Protein

Threonine-rich inner membrane protein GfcA

Gene

gfcA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:G6508-MONOMER.
ECOL316407:JW5133-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Threonine-rich inner membrane protein GfcA
Alternative name(s):
Group 4 capsule protein A homolog
Gene namesi
Name:gfcA
Synonyms:ymcD
Ordered Locus Names:b0987, JW5133
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13732. gfcA.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini22 – 59CytoplasmicSequence analysisAdd BLAST38
Transmembranei60 – 80HelicalSequence analysisAdd BLAST21
Topological domaini81 – 101PeriplasmicSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000016879922 – 101Threonine-rich inner membrane protein GfcAAdd BLAST80

Proteomic databases

PaxDbiP75885.
PRIDEiP75885.

Interactioni

Protein-protein interaction databases

BioGridi4262044. 9 interactors.
DIPiDIP-12710N.
IntActiP75885. 1 interactor.
STRINGi511145.b0987.

Structurei

3D structure databases

ProteinModelPortaliP75885.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi15 – 100Thr-richAdd BLAST86

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000009401.
OMAiKRKVMKH.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P75885-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKHKLSAILM AFMLTTPAAF AAPEATNGTE ATTGTTGTTT TTTGATTTAT
60 70 80 90 100
TTGGVAAGAV GTATVVGVAT AVGVATLAVV AANDSGDGGS HNTSTTTSTT

R
Length:101
Mass (Da):9,508
Last modified:November 13, 2007 - v2
Checksum:iAE3E86C5E6166C83
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74072.2.
AP009048 Genomic DNA. Translation: BAA35752.1.
PIRiA64840.
RefSeqiNP_415507.2. NC_000913.3.
WP_001295358.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74072; AAC74072; b0987.
BAA35752; BAA35752; BAA35752.
GeneIDi945029.
KEGGiecj:JW5133.
eco:b0987.
PATRICi32117197. VBIEscCol129921_1022.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74072.2.
AP009048 Genomic DNA. Translation: BAA35752.1.
PIRiA64840.
RefSeqiNP_415507.2. NC_000913.3.
WP_001295358.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP75885.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262044. 9 interactors.
DIPiDIP-12710N.
IntActiP75885. 1 interactor.
STRINGi511145.b0987.

Proteomic databases

PaxDbiP75885.
PRIDEiP75885.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74072; AAC74072; b0987.
BAA35752; BAA35752; BAA35752.
GeneIDi945029.
KEGGiecj:JW5133.
eco:b0987.
PATRICi32117197. VBIEscCol129921_1022.

Organism-specific databases

EchoBASEiEB3496.
EcoGeneiEG13732. gfcA.

Phylogenomic databases

HOGENOMiHOG000009401.
OMAiKRKVMKH.

Enzyme and pathway databases

BioCyciEcoCyc:G6508-MONOMER.
ECOL316407:JW5133-MONOMER.

Miscellaneous databases

PROiP75885.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiGFCA_ECOLI
AccessioniPrimary (citable) accession number: P75885
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 13, 2007
Last modified: November 2, 2016
This is version 104 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

In E.coli K12 / MG1655 and K12 / W3110 this operon is silenced by an IS1D insertion in the promoter region.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.