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Protein

Uncharacterized lipoprotein GfcB

Gene

gfcB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:G6507-MONOMER.
ECOL316407:JW0969-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized lipoprotein GfcB
Alternative name(s):
Group 4 capsule protein B homolog
Gene namesi
Name:gfcB
Synonyms:ymcC
Ordered Locus Names:b0986, JW0969
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13731. gfcB.

Subcellular locationi

  • Cell membrane PROSITE-ProRule annotation; Lipid-anchor PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1515PROSITE-ProRule annotationAdd
BLAST
Chaini16 – 214199Uncharacterized lipoprotein GfcBPRO_0000018055Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi16 – 161N-palmitoyl cysteinePROSITE-ProRule annotation
Lipidationi16 – 161S-diacylglycerol cysteinePROSITE-ProRule annotation

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiP75884.
PRIDEiP75884.

Interactioni

Protein-protein interaction databases

DIPiDIP-12709N.
IntActiP75884. 1 interaction.
MINTiMINT-1301421.
STRINGi511145.b0986.

Structurei

Secondary structure

1
214
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi23 – 3311Combined sources
Helixi41 – 466Combined sources
Beta strandi51 – 566Combined sources
Beta strandi62 – 709Combined sources
Beta strandi73 – 775Combined sources
Beta strandi83 – 875Combined sources
Beta strandi90 – 9910Combined sources
Beta strandi101 – 1066Combined sources
Helixi107 – 1093Combined sources
Helixi111 – 1177Combined sources
Beta strandi123 – 13210Combined sources
Beta strandi135 – 15521Combined sources
Beta strandi158 – 17114Combined sources
Turni172 – 1754Combined sources
Beta strandi176 – 18510Combined sources
Turni186 – 1883Combined sources
Beta strandi191 – 20111Combined sources
Beta strandi203 – 2097Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2IN5X-ray2.30A/B17-214[»]
ProteinModelPortaliP75884.
SMRiP75884. Positions 18-214.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP75884.

Family & Domainsi

Sequence similaritiesi

To E.coli YjbF.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4108Y9B. Bacteria.
ENOG4111IXI. LUCA.
HOGENOMiHOG000280367.
OMAiPANAGIP.
OrthoDBiEOG6P335M.

Family and domain databases

Gene3Di2.40.360.10. 1 hit.
InterProiIPR021308. GfcB.
IPR023373. YmcC_dom.
[Graphical view]
PfamiPF11102. YjbF. 1 hit.
[Graphical view]
SUPFAMiSSF159270. SSF159270. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P75884-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPLILSIFA LFLAGCTHSQ QSMVDTFRAS LFDNQDITVA DQQIQALPYS
60 70 80 90 100
TMYLRLNEGQ RIFVVLGYIE QEQSKWLSQD NAMLVTHNGR LLKTVKLNNN
110 120 130 140 150
LLEVTNSGQD PLRNALAIKD GSRWTRDILW SEDNHFRSAT LSSTFSFAGL
160 170 180 190 200
ETLNIAGRNV LCNVWQEEVT STRPEKQWQN TFWVDSATGQ VRQSRQMLGA
210
GVIPVEMTFL KPAP
Length:214
Mass (Da):24,268
Last modified:February 1, 1997 - v1
Checksum:i77A3111CBAF3E90D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74071.1.
AP009048 Genomic DNA. Translation: BAA35751.1.
PIRiH64839.
RefSeqiNP_415506.1. NC_000913.3.
WP_001247610.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74071; AAC74071; b0986.
BAA35751; BAA35751; BAA35751.
GeneIDi949118.
KEGGiecj:JW0969.
eco:b0986.
PATRICi32117195. VBIEscCol129921_1021.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74071.1.
AP009048 Genomic DNA. Translation: BAA35751.1.
PIRiH64839.
RefSeqiNP_415506.1. NC_000913.3.
WP_001247610.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2IN5X-ray2.30A/B17-214[»]
ProteinModelPortaliP75884.
SMRiP75884. Positions 18-214.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-12709N.
IntActiP75884. 1 interaction.
MINTiMINT-1301421.
STRINGi511145.b0986.

Proteomic databases

PaxDbiP75884.
PRIDEiP75884.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74071; AAC74071; b0986.
BAA35751; BAA35751; BAA35751.
GeneIDi949118.
KEGGiecj:JW0969.
eco:b0986.
PATRICi32117195. VBIEscCol129921_1021.

Organism-specific databases

EchoBASEiEB3495.
EcoGeneiEG13731. gfcB.

Phylogenomic databases

eggNOGiENOG4108Y9B. Bacteria.
ENOG4111IXI. LUCA.
HOGENOMiHOG000280367.
OMAiPANAGIP.
OrthoDBiEOG6P335M.

Enzyme and pathway databases

BioCyciEcoCyc:G6507-MONOMER.
ECOL316407:JW0969-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP75884.
PROiP75884.

Family and domain databases

Gene3Di2.40.360.10. 1 hit.
InterProiIPR021308. GfcB.
IPR023373. YmcC_dom.
[Graphical view]
PfamiPF11102. YjbF. 1 hit.
[Graphical view]
SUPFAMiSSF159270. SSF159270. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Crystal structure of the hypothetical lipoprotein ymcC from Escherichia coli (K12), Northeast structural genomics target ER552."
    Northeast structural genomics consortium (NESG)
    Submitted (NOV-2006) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 17-214.

Entry informationi

Entry nameiGFCB_ECOLI
AccessioniPrimary (citable) accession number: P75884
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 11, 2015
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

In E.coli K12 / MG1655 and K12 / W3110 this operon is silenced by an IS1D insertion in the promoter region.Curated

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.