P75883 (GFCC_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein gfcC

Alternative name(s):
Group 4 capsule protein C homolog

Gene names

Name:	gfcC
Synonyms:	ymcB
Ordered Locus Names:	b0985, JW0968

Organism

Escherichia coli (strain K12)

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	248 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities	To E.coli yjbG.
Caution	In E.coli K12 / MG1655 and K12 / W3110 this operon is silenced by an IS1D insertion in the promoter region.

Ontologies

Keywords
Domain	Signal
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 22	22	Potential
	Chain	23 – 248	226	Uncharacterized protein gfcC		PRO_0000013816

Sequences

	Sequence		Length	Mass (Da)
	P75883 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 74F5B38825C4587B	FASTA	248	27,296
	10 20 30 40 50 60 MNKLQSYFIA SVLYVMTPHA FAQGTVTIYL PGEQQTLSVG PVENVVQLVT QPQLRDRLWW 70 80 90 100 110 120 PGALLTDSAA KAKALKDYQH VMAQLASWEA EADDDVAATI KSVRQQLLNL NITGRLPVKL 130 140 150 160 170 180 DPDFVRVDEN SNPPLVGDYT LYTVQRPVTI TLLGAVSGAG QLPWQAGRSV TDYLQDHPRL 190 200 210 220 230 240 AGADKNNVMV ITPEGETVVA PVALWNKRHV EPPPGSQLWL GFSAHVLPEK YADLNDQIVS VLTQRVPD

References

[1]	"A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K., Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S., Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K. , Mori H., Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G., Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M., Horiuchi T. DNA Res. 3:137-155(1996) [PubMed: 8905232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00096 Genomic DNA. Translation: AAC74070.1. AP009048 Genomic DNA. Translation: BAA35750.2.
PIR	G64839.
RefSeq	NP_415505.1. NC_000913.2.
3D structure databases
ProteinModelPortal	P75883.
SMR	P75883. Positions 23-248.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-12708N.
IntAct	P75883. 1 interaction.
MINT	MINT-1302737.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000003717; EBESCP00000003717; EBESCG00000003038. EBESCT00000018037; EBESCP00000017328; EBESCG00000017093.
GeneID	944978.
GenomeReviews	Gene locus JW0968 in contig AP009048_GR. Gene locus b0985 in contig U00096_GR.
KEGG	ecj:JW0968. eco:b0985.
PATRIC	32117193. VBIEscCol129921_1020.
Organism-specific databases
EchoBASE	EB3494.
EcoGene	EG13730. gfcC.
Phylogenomic databases
eggNOG	NOG10375.
GeneTree	EBGT00050000009132.
HOGENOM	HBG416875.
OMA	FSANNEF.
ProtClustDB	CLSK879893.
Enzyme and pathway databases
BioCyc	EcoCyc:G6506-MONOMER.
Gene expression databases
Genevestigator	P75883.
Family and domain databases
InterPro	IPR010425. DUF1017. [Graphical view]
Pfam	PF06251. DUF1017. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GFCC_ECOLI

Accession

Primary (citable) accession number: P75883
Secondary accession number(s): Q9Z3A3

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program