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Protein

Inner membrane protein YccS

Gene

yccS

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:G6495-MONOMER.
ECOL316407:JW5128-MONOMER.

Protein family/group databases

TCDBi2.A.85.1.1. the aromatic acid exporter (arae) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane protein YccS
Gene namesi
Name:yccS
Ordered Locus Names:b0960, JW5128
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13721. yccS.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 10PeriplasmicSequence analysis10
Transmembranei11 – 31HelicalSequence analysisAdd BLAST21
Topological domaini32CytoplasmicSequence analysis1
Transmembranei33 – 53HelicalSequence analysisAdd BLAST21
Topological domaini54 – 66PeriplasmicSequence analysisAdd BLAST13
Transmembranei67 – 87HelicalSequence analysisAdd BLAST21
Topological domaini88CytoplasmicSequence analysis1
Transmembranei89 – 109HelicalSequence analysisAdd BLAST21
Topological domaini110 – 112PeriplasmicSequence analysis3
Transmembranei113 – 133HelicalSequence analysisAdd BLAST21
Topological domaini134 – 142CytoplasmicSequence analysis9
Transmembranei143 – 163HelicalSequence analysisAdd BLAST21
Topological domaini164 – 398PeriplasmicSequence analysisAdd BLAST235
Transmembranei399 – 419HelicalSequence analysisAdd BLAST21
Topological domaini420 – 441CytoplasmicSequence analysisAdd BLAST22
Transmembranei442 – 462HelicalSequence analysisAdd BLAST21
Topological domaini463 – 465PeriplasmicSequence analysis3
Transmembranei466 – 486HelicalSequence analysisAdd BLAST21
Topological domaini487 – 489CytoplasmicSequence analysis3
Transmembranei490 – 510HelicalSequence analysisAdd BLAST21
Topological domaini511 – 512PeriplasmicSequence analysis2
Transmembranei513 – 533HelicalSequence analysisAdd BLAST21
Topological domaini534 – 717CytoplasmicSequence analysisAdd BLAST184

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001687931 – 717Inner membrane protein YccSAdd BLAST717

Proteomic databases

PaxDbiP75870.
PRIDEiP75870.

Interactioni

Protein-protein interaction databases

BioGridi4263155. 284 interactors.
DIPiDIP-11498N.
IntActiP75870. 1 interactor.
STRINGi511145.b0960.

Structurei

3D structure databases

ProteinModelPortaliP75870.
SMRiP75870.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YccS/YhfK family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EM2. Bacteria.
COG1289. LUCA.
HOGENOMiHOG000279479.
InParanoidiP75870.
OMAiYSTIAFG.
PhylomeDBiP75870.

Family and domain databases

InterProiIPR010019. Integral_membrane_YccS.
IPR010020. Integral_membrane_YCCS_YHJK.
IPR032692. YccS_N.
[Graphical view]
PfamiPF12805. FUSC-like. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01666. YCCS. 1 hit.
TIGR01667. YCCS_YHJK. 1 hit.

Sequencei

Sequence statusi: Complete.

P75870-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSPLLKRYT WNSAWLYYAR IFIALCGTTA FPWWLGDVKL TIPLTLGMVA
60 70 80 90 100
AALTDLDDRL AGRLRNLIIT LFCFFIASAS VELLFPWPWL FAIGLTLSTS
110 120 130 140 150
GFILLGGLGQ RYATIAFGAL LIAIYTMLGT SLYEHWYQQP MYLLAGAVWY
160 170 180 190 200
NVLTLIGHLL FPVRPLQDNL ARCYEQLARY LELKSRMFDP DIEDQSQAPL
210 220 230 240 250
YDLALANGLL MATLNQTKLS LLTRLRGDRG QRGTRRTLHY YFVAQDIHER
260 270 280 290 300
ASSSHIQYQT LREHFRHSDV LFRFQRLMSM QGQACQQLSR CILLRQPYQH
310 320 330 340 350
DPHFERAFTH IDAALERMRD NGAPADLLKT LGFLLNNLRA IDAQLATIES
360 370 380 390 400
EQAQALPHNN DENELADDSP HGLSDIWLRL SRHFTPESAL FRHAVRMSLV
410 420 430 440 450
LCFGYAIIQI TGMHHGYWIL LTSLFVCQPN YNATRHRLKL RIIGTLVGIA
460 470 480 490 500
IGIPVLWFVP SLEGQLVLLV ITGVLFFAFR NVQYAHATMF ITLLVLLCFN
510 520 530 540 550
LLGEGFEVAL PRVIDTLIGC AIAWAAVSYI WPDWQFRNLP RMLERATEAN
560 570 580 590 600
CRYLDAILEQ YHQGRDNRLA YRIARRDAHN RDAELASVVS NMSSEPNVTP
610 620 630 640 650
QIREAAFRLL CLNHTFTSYI SALGAHREQL TNPEILAFLD DAVCYVDDAL
660 670 680 690 700
HHQPADEERV NEALASLKQR MQQLEPRADS KEPLVVQQVG LLIALLPEIG
710
RLQRQITQVP QETPVSA
Length:717
Mass (Da):81,668
Last modified:April 27, 2001 - v2
Checksum:i8EC99A6850EFAD5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74046.2.
AP009048 Genomic DNA. Translation: BAA35718.2.
PIRiG64836.
RefSeqiNP_415480.2. NC_000913.3.
WP_001382153.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74046; AAC74046; b0960.
BAA35718; BAA35718; BAA35718.
GeneIDi947001.
KEGGiecj:JW5128.
eco:b0960.
PATRICi32117139. VBIEscCol129921_0994.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74046.2.
AP009048 Genomic DNA. Translation: BAA35718.2.
PIRiG64836.
RefSeqiNP_415480.2. NC_000913.3.
WP_001382153.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP75870.
SMRiP75870.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263155. 284 interactors.
DIPiDIP-11498N.
IntActiP75870. 1 interactor.
STRINGi511145.b0960.

Protein family/group databases

TCDBi2.A.85.1.1. the aromatic acid exporter (arae) family.

Proteomic databases

PaxDbiP75870.
PRIDEiP75870.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74046; AAC74046; b0960.
BAA35718; BAA35718; BAA35718.
GeneIDi947001.
KEGGiecj:JW5128.
eco:b0960.
PATRICi32117139. VBIEscCol129921_0994.

Organism-specific databases

EchoBASEiEB3485.
EcoGeneiEG13721. yccS.

Phylogenomic databases

eggNOGiENOG4105EM2. Bacteria.
COG1289. LUCA.
HOGENOMiHOG000279479.
InParanoidiP75870.
OMAiYSTIAFG.
PhylomeDBiP75870.

Enzyme and pathway databases

BioCyciEcoCyc:G6495-MONOMER.
ECOL316407:JW5128-MONOMER.

Miscellaneous databases

PROiP75870.

Family and domain databases

InterProiIPR010019. Integral_membrane_YccS.
IPR010020. Integral_membrane_YCCS_YHJK.
IPR032692. YccS_N.
[Graphical view]
PfamiPF12805. FUSC-like. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01666. YCCS. 1 hit.
TIGR01667. YCCS_YHJK. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYCCS_ECOLI
AccessioniPrimary (citable) accession number: P75870
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: April 27, 2001
Last modified: November 2, 2016
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.