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Protein

Putative Lon protease homolog

Gene

ycbZ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei438By similarity1
Active sitei481By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Serine protease

Enzyme and pathway databases

BioCyciEcoCyc:G6493-MONOMER

Protein family/group databases

MEROPSiS16.A10

Names & Taxonomyi

Protein namesi
Recommended name:
Putative Lon protease homolog (EC:3.4.21.-)
Alternative name(s):
ATP-dependent protease La homolog
Gene namesi
Name:ycbZ
Ordered Locus Names:b0955, JW0938
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13718 ycbZ

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000761481 – 586Putative Lon protease homologAdd BLAST586

Proteomic databases

PaxDbiP75867
PRIDEiP75867

Interactioni

Protein-protein interaction databases

BioGridi4260030, 40 interactors
DIPiDIP-11487N
STRINGi316385.ECDH10B_1025

Structurei

3D structure databases

ProteinModelPortaliP75867
SMRiP75867
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini346 – 543Lon proteolyticPROSITE-ProRule annotationAdd BLAST198

Domaini

Lacks the ATP-binding domain.

Sequence similaritiesi

Belongs to the peptidase S16 family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105DAN Bacteria
COG1067 LUCA
HOGENOMiHOG000277817
InParanoidiP75867
KOiK04770
OMAiGFFTICQ
PhylomeDBiP75867

Family and domain databases

Gene3Di3.30.230.10, 1 hit
InterProiView protein in InterPro
IPR008269 Lon_proteolytic
IPR027065 Lon_Prtase
IPR020568 Ribosomal_S5_D2-typ_fold
IPR014721 Ribosomal_S5_D2-typ_fold_subgr
PANTHERiPTHR10046 PTHR10046, 1 hit
PfamiView protein in Pfam
PF05362 Lon_C, 1 hit
SUPFAMiSSF54211 SSF54211, 1 hit
PROSITEiView protein in PROSITE
PS51786 LON_PROTEOLYTIC, 1 hit

Sequencei

Sequence statusi: Complete.

P75867-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTITKLAWRD LVPDTDSYQE IFAQPHLIDE NDPLFSDTQP RLQFALEQLL
60 70 80 90 100
HTRASSSFML AKAPEESEYL NLIANAARTL QSDAGQLVGG HYEVSGHSIR
110 120 130 140 150
LRHAVSADDN FATLTQVVAA DWVEAEQLFG CLRQFNGDIT LQPGLVHQAN
160 170 180 190 200
GGILIISLRT LLAQPLLWMR LKNIVNRERF DWVAFDESRP LPVSVPSMPL
210 220 230 240 250
KLKVILVGER ESLADFQEME PELSEQAIYS EFEDTLQIVD AESVTQWCRW
260 270 280 290 300
VTFTARHNHL PAPGADAWPI LIREAARYTG EQETLPLSPQ WILRQCKEVA
310 320 330 340 350
SLCDGDTFSG EQLNLMLQQR EWREGFLAER MQDEILQEQI LIETEGERIG
360 370 380 390 400
QINALSVIEF PGHPRAFGEP SRISCVVHIG DGEFTDIERK AELGGNIHAK
410 420 430 440 450
GMMIMQAFLM SELQLEQQIP FSASLTFEQS YSEVDGDSAS MAELCALISA
460 470 480 490 500
LADVPVNQSI AITGSVDQFG RAQPVGGLNE KIEGFFAICQ QRELTGKQGV
510 520 530 540 550
IIPTANVRHL SLHSELVKAV EEGKFTIWAV DDVTDALPLL LNLVWDGEGQ
560 570 580
TTLMQTIQER IAQASQQEGR HRFPWPLRWL NWFIPN
Length:586
Mass (Da):65,819
Last modified:February 1, 1997 - v1
Checksum:i442AAEADDB87B59F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74041.1
AP009048 Genomic DNA Translation: BAA35713.1
PIRiB64836
RefSeqiNP_415475.1, NC_000913.3
WP_000156518.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74041; AAC74041; b0955
BAA35713; BAA35713; BAA35713
GeneIDi945569
KEGGiecj:JW0938
eco:b0955
PATRICifig|1411691.4.peg.1319

Similar proteinsi

Entry informationi

Entry nameiLONH_ECOLI
AccessioniPrimary (citable) accession number: P75867
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health