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Protein

Probable outer membrane usher protein ElfC

Gene

elfC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be involved in the export and assembly of the ElfA fimbrial subunits across the outer membrane.1 Publication

GO - Molecular functioni

GO - Biological processi

  • pilus assembly Source: GO_Central
  • pilus organization Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Fimbrium biogenesis, Transport

Enzyme and pathway databases

BioCyciEcoCyc:G6482-MONOMER.
ECOL316407:JW0923-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable outer membrane usher protein ElfC
Gene namesi
Name:elfC
Synonyms:ycbS
Ordered Locus Names:b0940, JW0923
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13711. elfC.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3535Sequence analysisAdd
BLAST
Chaini36 – 866831Probable outer membrane usher protein ElfCPRO_0000009330Add
BLAST

Proteomic databases

PaxDbiP75857.
PRIDEiP75857.

Expressioni

Inductioni

Expression is negatively regulated by H-NS and subjected to cAMP receptor protein (CRP)-mediated catabolite repression.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4263120. 168 interactions.
STRINGi511145.b0940.

Structurei

3D structure databases

ProteinModelPortaliP75857.
SMRiP75857. Positions 61-866.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the fimbrial export usher family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

eggNOGiENOG4105CW0. Bacteria.
COG3188. LUCA.
HOGENOMiHOG000111414.
InParanoidiP75857.
KOiK07347.
OMAiICHISYE.
PhylomeDBiP75857.

Family and domain databases

InterProiIPR000015. Fimb_usher.
IPR018030. Fimbrial_membr_usher_CS.
IPR025949. PapC-like_C.
IPR025885. PapC_N.
[Graphical view]
PANTHERiPTHR30451. PTHR30451. 1 hit.
PfamiPF13953. PapC_C. 1 hit.
PF13954. PapC_N. 1 hit.
PF00577. Usher. 1 hit.
[Graphical view]
PROSITEiPS01151. FIMBRIAL_USHER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P75857-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYRTHRQHSL LSSGGVPSFI GGLVVFVSAA FNAQAETWFD PAFFKDDPSM
60 70 80 90 100
VADLSRFEKG QKITPGVYRV DIVLNQTIVD TRNVNFVEIT PEKGIAACLT
110 120 130 140 150
TESLDAMGVN TDAFPAFKQL DKQACVPLAE IIPDASVTFN VNKLRLEISV
160 170 180 190 200
PQIAIKSNAR GYVPPERWDE GINALLLGYS FSGANSIHSS ADSDSGDSYF
210 220 230 240 250
LNLNSGVNLG PWRLRNNSTW SRSSGQTAEW KNLSSYLQRA VIPLKGELTV
260 270 280 290 300
GDDYTAGDFF DSVSFRGVQL ASDDNMLPDS LKGFAPVVRG IAKSNAQITI
310 320 330 340 350
KQNGYTIYQT YVSPGAFEIS DLYSTSSSGD LLVEIKEADG SVNSYSVPFS
360 370 380 390 400
SVPLLQRQGR IKYAVTLAKY RTNSNEQQES KFAQATLQWG GPWGTTWYGG
410 420 430 440 450
GQYAEYYRAA MFGLGFNLGD FGAISFDATQ AKSTLADQSE HKGQSYRFLY
460 470 480 490 500
AKTLNHLGTN FQLMGYRYST SGFYTLSDTM YKHMDGYEFN DGDDEDTPMW
510 520 530 540 550
SRYYNLFYTK RGKLQVNISQ QLGEYGSFYL SGSQQTYWHT DQQDRLLQFG
560 570 580 590 600
YNTQIKDLSL GISWNYSKSR GQPDADQVFA LNFSLPLNLL LPRSNDSYTR
610 620 630 640 650
KKNYAWMTSN TSIDNEGHTT QNLGLTETLL DDGNLSYSVQ QGYNSEGKTA
660 670 680 690 700
NGSASMDYKG AFADARVGYN YSDNGSQQQL NYALSGSLVA HSQGITLGQS
710 720 730 740 750
LGETNVLIAA PGAENTRVAN STGLKTDWRG YTVVPYATSY RENRIALDAA
760 770 780 790 800
SLKRNVDLEN AVVNVVPTKG ALVLAEFNAH AGARVLMKTS KQGIPLRFGA
810 820 830 840 850
IATLDGVQAN SGIIDDDGSL YMAGLPAKGT ISVRWGEAPD QICHINYELT
860
EQQINSAITR MDAICR
Length:866
Mass (Da):95,242
Last modified:February 1, 1997 - v1
Checksum:i0004DC5E9F1F5796
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74026.1.
AP009048 Genomic DNA. Translation: BAA35695.1.
PIRiC64834.
RefSeqiNP_415460.1. NC_000913.3.
WP_000286312.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74026; AAC74026; b0940.
BAA35695; BAA35695; BAA35695.
GeneIDi946934.
KEGGiecj:JW0923.
eco:b0940.
PATRICi32117099. VBIEscCol129921_0974.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74026.1.
AP009048 Genomic DNA. Translation: BAA35695.1.
PIRiC64834.
RefSeqiNP_415460.1. NC_000913.3.
WP_000286312.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP75857.
SMRiP75857. Positions 61-866.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263120. 168 interactions.
STRINGi511145.b0940.

Proteomic databases

PaxDbiP75857.
PRIDEiP75857.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74026; AAC74026; b0940.
BAA35695; BAA35695; BAA35695.
GeneIDi946934.
KEGGiecj:JW0923.
eco:b0940.
PATRICi32117099. VBIEscCol129921_0974.

Organism-specific databases

EchoBASEiEB3475.
EcoGeneiEG13711. elfC.

Phylogenomic databases

eggNOGiENOG4105CW0. Bacteria.
COG3188. LUCA.
HOGENOMiHOG000111414.
InParanoidiP75857.
KOiK07347.
OMAiICHISYE.
PhylomeDBiP75857.

Enzyme and pathway databases

BioCyciEcoCyc:G6482-MONOMER.
ECOL316407:JW0923-MONOMER.

Miscellaneous databases

PROiP75857.

Family and domain databases

InterProiIPR000015. Fimb_usher.
IPR018030. Fimbrial_membr_usher_CS.
IPR025949. PapC-like_C.
IPR025885. PapC_N.
[Graphical view]
PANTHERiPTHR30451. PTHR30451. 1 hit.
PfamiPF13953. PapC_C. 1 hit.
PF13954. PapC_N. 1 hit.
PF00577. Usher. 1 hit.
[Graphical view]
PROSITEiPS01151. FIMBRIAL_USHER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiELFC_ECOLI
AccessioniPrimary (citable) accession number: P75857
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: September 7, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

The operon is cryptic under classical laboratory conditions, but is functional when constitutively expressed.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.