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Protein

Uncharacterized HTH-type transcriptional regulator YcaN

Gene

ycaN

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi20 – 40H-T-H motifPROSITE-ProRule annotationAdd BLAST21

GO - Molecular functioni

GO - Biological processi

  • transcription, DNA-templated Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6467-MONOMER.
ECOL316407:JW0883-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YcaN
Gene namesi
Name:ycaN
Ordered Locus Names:b0900, JW0883
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13698. ycaN.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001057811 – 302Uncharacterized HTH-type transcriptional regulator YcaNAdd BLAST302

Proteomic databases

PaxDbiP75836.
PRIDEiP75836.

Interactioni

Protein-protein interaction databases

BioGridi4261671. 17 interactors.
STRINGi511145.b0900.

Structurei

3D structure databases

ProteinModelPortaliP75836.
SMRiP75836.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 60HTH lysR-typePROSITE-ProRule annotationAdd BLAST60

Sequence similaritiesi

Contains 1 HTH lysR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410642W. Bacteria.
ENOG410XSPG. LUCA.
HOGENOMiHOG000233519.
InParanoidiP75836.
OMAiDWITERP.
PhylomeDBiP75836.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P75836-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRMNMSDFAT FFAVARNQSF RAAGDELGLS SSAISHSIKT LEQRLKIRLF
60 70 80 90 100
NRTTRSVSLT EAGSNLYERL RPAFDEIQIM LDEMNDFRLT PTGTLKINAA
110 120 130 140 150
RVAARIFLMS LLVGFTREYP DIKVELTTDD SLVDIVQQGF DAGVRLSCIV
160 170 180 190 200
EKDMISVAIG PPVKLCVAAT PEYFARYGKP RHPHDLLNHQ CVVFRYPSGK
210 220 230 240 250
PFHWQFAKEL EIAVAGNIIL DDVDAELEAV LMGAGIGYLL YEQIKEYLDT
260 270 280 290 300
GRLECVLEDW STERPGFQIY YPNRQYMSCG LRAFLDYVKT GQICQSQRHR

PQ
Length:302
Mass (Da):34,294
Last modified:February 1, 1997 - v1
Checksum:i8FFF02FB02B24B73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73986.1.
AP009048 Genomic DNA. Translation: BAA35635.1.
PIRiC64829.
RefSeqiNP_415420.1. NC_000913.3.
WP_001242684.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73986; AAC73986; b0900.
BAA35635; BAA35635; BAA35635.
GeneIDi945523.
KEGGiecj:JW0883.
eco:b0900.
PATRICi32117013. VBIEscCol129921_0931.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73986.1.
AP009048 Genomic DNA. Translation: BAA35635.1.
PIRiC64829.
RefSeqiNP_415420.1. NC_000913.3.
WP_001242684.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP75836.
SMRiP75836.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261671. 17 interactors.
STRINGi511145.b0900.

Proteomic databases

PaxDbiP75836.
PRIDEiP75836.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73986; AAC73986; b0900.
BAA35635; BAA35635; BAA35635.
GeneIDi945523.
KEGGiecj:JW0883.
eco:b0900.
PATRICi32117013. VBIEscCol129921_0931.

Organism-specific databases

EchoBASEiEB3462.
EcoGeneiEG13698. ycaN.

Phylogenomic databases

eggNOGiENOG410642W. Bacteria.
ENOG410XSPG. LUCA.
HOGENOMiHOG000233519.
InParanoidiP75836.
OMAiDWITERP.
PhylomeDBiP75836.

Enzyme and pathway databases

BioCyciEcoCyc:G6467-MONOMER.
ECOL316407:JW0883-MONOMER.

Miscellaneous databases

PROiP75836.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYCAN_ECOLI
AccessioniPrimary (citable) accession number: P75836
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.