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P75806

- YBJG_ECOLI

UniProt

P75806 - YBJG_ECOLI

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Protein
Putative undecaprenyl-diphosphatase YbjG
Gene
ybjG, b0841, JW5112
Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Overexpression leads to increased undecaprenyl diphosphatase activity and to increased resistance to bacitracin. May have a preferred substrate other than undecaprenyl diphosphate in vivo.1 Publication

Catalytic activityi

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate.

GO - Molecular functioni

  1. undecaprenyl-diphosphatase activity Source: EcoCyc

GO - Biological processi

  1. peptidoglycan biosynthetic process Source: UniProtKB-KW
  2. regulation of cell shape Source: UniProtKB-KW
  3. response to antibiotic Source: EcoCyc
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Antibiotic resistance, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciEcoCyc:G6439-MONOMER.
ECOL316407:JW5112-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative undecaprenyl-diphosphatase YbjG (EC:3.6.1.27)
Alternative name(s):
Undecaprenyl pyrophosphate phosphatase
Gene namesi
Name:ybjG
Ordered Locus Names:b0841, JW5112
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG13676. ybjG.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2727Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei28 – 4821Helical; Reviewed prediction
Add
BLAST
Topological domaini49 – 579Periplasmic Reviewed prediction
Transmembranei58 – 7821Helical; Reviewed prediction
Add
BLAST
Topological domaini79 – 12042Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei121 – 14323Helical; Reviewed prediction
Add
BLAST
Topological domaini144 – 1496Periplasmic Reviewed prediction
Transmembranei150 – 17223Helical; Reviewed prediction
Add
BLAST
Topological domaini173 – 19826Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 198198Putative undecaprenyl-diphosphatase YbjG
PRO_0000168739Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP75806.

Interactioni

Protein-protein interaction databases

STRINGi511145.b0841.

Structurei

3D structure databases

ProteinModelPortaliP75806.

Family & Domainsi

Sequence similaritiesi

Belongs to the BcrC/YbjG family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0671.
HOGENOMiHOG000221066.
KOiK06153.
OMAiWHRVWSG.
OrthoDBiEOG661HBQ.
PhylomeDBiP75806.

Family and domain databases

Gene3Di1.20.144.10. 1 hit.
InterProiIPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view]
PfamiPF01569. PAP2. 1 hit.
[Graphical view]
SMARTiSM00014. acidPPc. 1 hit.
[Graphical view]
SUPFAMiSSF48317. SSF48317. 1 hit.

Sequencei

Sequence statusi: Complete.

P75806-1 [UniParc]FASTAAdd to Basket

« Hide

MLENLNLSLF SLINATPDSA PWMISLAIFI AKDLITVVPL LAVVLWLWGL    50
TAQRQLVIKI AIALAVSLFV SWTMGHLFPH DRPFVENIGY NFLHHAADDS 100
FPSDHGTVIF TFALAFLCWH RLWSGSLLMV LAVVIAWSRV YLGVHWPLDM 150
LGGLLAGMIG CLSAQIIWQA MGHKLYQRLQ SWYRVCFALP IRKGWVRD 198
Length:198
Mass (Da):22,399
Last modified:February 1, 1997 - v1
Checksum:iA1ED7A934F78A15D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00096 Genomic DNA. Translation: AAC73928.1.
AP009048 Genomic DNA. Translation: BAA35544.1.
PIRiA64822.
RefSeqiNP_415362.1. NC_000913.3.
YP_489114.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC73928; AAC73928; b0841.
BAA35544; BAA35544; BAA35544.
GeneIDi12933833.
945450.
KEGGiecj:Y75_p0814.
eco:b0841.
PATRICi32116885. VBIEscCol129921_0868.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00096 Genomic DNA. Translation: AAC73928.1 .
AP009048 Genomic DNA. Translation: BAA35544.1 .
PIRi A64822.
RefSeqi NP_415362.1. NC_000913.3.
YP_489114.1. NC_007779.1.

3D structure databases

ProteinModelPortali P75806.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 511145.b0841.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC73928 ; AAC73928 ; b0841 .
BAA35544 ; BAA35544 ; BAA35544 .
GeneIDi 12933833.
945450.
KEGGi ecj:Y75_p0814.
eco:b0841.
PATRICi 32116885. VBIEscCol129921_0868.

Organism-specific databases

EchoBASEi EB3440.
EcoGenei EG13676. ybjG.

Phylogenomic databases

eggNOGi COG0671.
HOGENOMi HOG000221066.
KOi K06153.
OMAi WHRVWSG.
OrthoDBi EOG661HBQ.
PhylomeDBi P75806.

Enzyme and pathway databases

BioCyci EcoCyc:G6439-MONOMER.
ECOL316407:JW5112-MONOMER.

Miscellaneous databases

PROi P75806.

Gene expression databases

Genevestigatori P75806.

Family and domain databases

Gene3Di 1.20.144.10. 1 hit.
InterProi IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view ]
Pfami PF01569. PAP2. 1 hit.
[Graphical view ]
SMARTi SM00014. acidPPc. 1 hit.
[Graphical view ]
SUPFAMi SSF48317. SSF48317. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Identification of multiple genes encoding membrane proteins with undecaprenyl pyrophosphate phosphatase (UppP) activity in Escherichia coli."
    El Ghachi M., Derbise A., Bouhss A., Mengin-Lecreulx D.
    J. Biol. Chem. 280:18689-18695(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  5. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYBJG_ECOLI
AccessioniPrimary (citable) accession number: P75806
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: May 14, 2014
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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