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Protein

Putative undecaprenyl-diphosphatase YbjG

Gene

ybjG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Overexpression leads to increased undecaprenyl diphosphatase activity and to increased resistance to bacitracin. May have a preferred substrate other than undecaprenyl diphosphate in vivo.1 Publication

Catalytic activityi

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate.

GO - Molecular functioni

  • undecaprenyl-diphosphatase activity Source: EcoCyc

GO - Biological processi

  • cell wall organization Source: UniProtKB-KW
  • peptidoglycan biosynthetic process Source: UniProtKB-KW
  • regulation of cell shape Source: UniProtKB-KW
  • response to antibiotic Source: EcoCyc

Keywordsi

Molecular functionHydrolase
Biological processAntibiotic resistance, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciEcoCyc:G6439-MONOMER
MetaCyc:G6439-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative undecaprenyl-diphosphatase YbjG (EC:3.6.1.27)
Alternative name(s):
Undecaprenyl pyrophosphate phosphatase
Gene namesi
Name:ybjG
Ordered Locus Names:b0841, JW5112
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13676 ybjG

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 27CytoplasmicSequence analysisAdd BLAST27
Transmembranei28 – 48HelicalSequence analysisAdd BLAST21
Topological domaini49 – 57PeriplasmicSequence analysis9
Transmembranei58 – 78HelicalSequence analysisAdd BLAST21
Topological domaini79 – 120CytoplasmicSequence analysisAdd BLAST42
Transmembranei121 – 143HelicalSequence analysisAdd BLAST23
Topological domaini144 – 149PeriplasmicSequence analysis6
Transmembranei150 – 172HelicalSequence analysisAdd BLAST23
Topological domaini173 – 198CytoplasmicSequence analysisAdd BLAST26

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001687391 – 198Putative undecaprenyl-diphosphatase YbjGAdd BLAST198

Proteomic databases

PaxDbiP75806
PRIDEiP75806

Interactioni

Protein-protein interaction databases

BioGridi4262827, 184 interactors
STRINGi316385.ECDH10B_0910

Structurei

3D structure databases

ProteinModelPortaliP75806
SMRiP75806
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BcrC/YbjG family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105D1E Bacteria
COG0671 LUCA
HOGENOMiHOG000221066
InParanoidiP75806
KOiK19302
OMAiNYTVFQW
PhylomeDBiP75806

Family and domain databases

CDDicd03385 PAP2_BcrC_like, 1 hit
InterProiView protein in InterPro
IPR036938 P_Acid_Pase_2/haloperoxi_sf
IPR000326 P_Acid_Pase_2/haloperoxidase
IPR033879 UPP_Pase
PfamiView protein in Pfam
PF01569 PAP2, 1 hit
SMARTiView protein in SMART
SM00014 acidPPc, 1 hit
SUPFAMiSSF48317 SSF48317, 1 hit

Sequencei

Sequence statusi: Complete.

P75806-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLENLNLSLF SLINATPDSA PWMISLAIFI AKDLITVVPL LAVVLWLWGL
60 70 80 90 100
TAQRQLVIKI AIALAVSLFV SWTMGHLFPH DRPFVENIGY NFLHHAADDS
110 120 130 140 150
FPSDHGTVIF TFALAFLCWH RLWSGSLLMV LAVVIAWSRV YLGVHWPLDM
160 170 180 190
LGGLLAGMIG CLSAQIIWQA MGHKLYQRLQ SWYRVCFALP IRKGWVRD
Length:198
Mass (Da):22,399
Last modified:February 1, 1997 - v1
Checksum:iA1ED7A934F78A15D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC73928.1
AP009048 Genomic DNA Translation: BAA35544.1
PIRiA64822
RefSeqiNP_415362.1, NC_000913.3
WP_001295291.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73928; AAC73928; b0841
BAA35544; BAA35544; BAA35544
GeneIDi945450
KEGGiecj:JW5112
eco:b0841
PATRICifig|1411691.4.peg.1437

Similar proteinsi

Entry informationi

Entry nameiYBJG_ECOLI
AccessioniPrimary (citable) accession number: P75806
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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