Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative undecaprenyl-diphosphatase YbjG

Gene

ybjG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Overexpression leads to increased undecaprenyl diphosphatase activity and to increased resistance to bacitracin. May have a preferred substrate other than undecaprenyl diphosphate in vivo.1 Publication

Catalytic activityi

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate.

GO - Molecular functioni

  • undecaprenyl-diphosphatase activity Source: EcoCyc

GO - Biological processi

  • cell wall organization Source: UniProtKB-KW
  • peptidoglycan biosynthetic process Source: UniProtKB-KW
  • regulation of cell shape Source: UniProtKB-KW
  • response to antibiotic Source: EcoCyc
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Antibiotic resistance, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciEcoCyc:G6439-MONOMER.
ECOL316407:JW5112-MONOMER.
MetaCyc:G6439-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative undecaprenyl-diphosphatase YbjG (EC:3.6.1.27)
Alternative name(s):
Undecaprenyl pyrophosphate phosphatase
Gene namesi
Name:ybjG
Ordered Locus Names:b0841, JW5112
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13676. ybjG.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 27CytoplasmicSequence analysisAdd BLAST27
Transmembranei28 – 48HelicalSequence analysisAdd BLAST21
Topological domaini49 – 57PeriplasmicSequence analysis9
Transmembranei58 – 78HelicalSequence analysisAdd BLAST21
Topological domaini79 – 120CytoplasmicSequence analysisAdd BLAST42
Transmembranei121 – 143HelicalSequence analysisAdd BLAST23
Topological domaini144 – 149PeriplasmicSequence analysis6
Transmembranei150 – 172HelicalSequence analysisAdd BLAST23
Topological domaini173 – 198CytoplasmicSequence analysisAdd BLAST26

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001687391 – 198Putative undecaprenyl-diphosphatase YbjGAdd BLAST198

Proteomic databases

PaxDbiP75806.
PRIDEiP75806.

Interactioni

Protein-protein interaction databases

BioGridi4262827. 183 interactors.
STRINGi511145.b0841.

Structurei

3D structure databases

ProteinModelPortaliP75806.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BcrC/YbjG family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105D1E. Bacteria.
COG0671. LUCA.
HOGENOMiHOG000221066.
InParanoidiP75806.
KOiK19302.
OMAiWHRVWSG.
PhylomeDBiP75806.

Family and domain databases

CDDicd03385. PAP2_BcrC_like. 1 hit.
Gene3Di1.20.144.10. 1 hit.
InterProiIPR000326. P_Acid_Pase_2/haloperoxidase.
IPR033879. UPP_Pase.
[Graphical view]
PfamiPF01569. PAP2. 1 hit.
[Graphical view]
SMARTiSM00014. acidPPc. 1 hit.
[Graphical view]
SUPFAMiSSF48317. SSF48317. 1 hit.

Sequencei

Sequence statusi: Complete.

P75806-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLENLNLSLF SLINATPDSA PWMISLAIFI AKDLITVVPL LAVVLWLWGL
60 70 80 90 100
TAQRQLVIKI AIALAVSLFV SWTMGHLFPH DRPFVENIGY NFLHHAADDS
110 120 130 140 150
FPSDHGTVIF TFALAFLCWH RLWSGSLLMV LAVVIAWSRV YLGVHWPLDM
160 170 180 190
LGGLLAGMIG CLSAQIIWQA MGHKLYQRLQ SWYRVCFALP IRKGWVRD
Length:198
Mass (Da):22,399
Last modified:February 1, 1997 - v1
Checksum:iA1ED7A934F78A15D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73928.1.
AP009048 Genomic DNA. Translation: BAA35544.1.
PIRiA64822.
RefSeqiNP_415362.1. NC_000913.3.
WP_001295291.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73928; AAC73928; b0841.
BAA35544; BAA35544; BAA35544.
GeneIDi945450.
KEGGiecj:JW5112.
eco:b0841.
PATRICi32116885. VBIEscCol129921_0868.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73928.1.
AP009048 Genomic DNA. Translation: BAA35544.1.
PIRiA64822.
RefSeqiNP_415362.1. NC_000913.3.
WP_001295291.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP75806.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262827. 183 interactors.
STRINGi511145.b0841.

Proteomic databases

PaxDbiP75806.
PRIDEiP75806.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73928; AAC73928; b0841.
BAA35544; BAA35544; BAA35544.
GeneIDi945450.
KEGGiecj:JW5112.
eco:b0841.
PATRICi32116885. VBIEscCol129921_0868.

Organism-specific databases

EchoBASEiEB3440.
EcoGeneiEG13676. ybjG.

Phylogenomic databases

eggNOGiENOG4105D1E. Bacteria.
COG0671. LUCA.
HOGENOMiHOG000221066.
InParanoidiP75806.
KOiK19302.
OMAiWHRVWSG.
PhylomeDBiP75806.

Enzyme and pathway databases

BioCyciEcoCyc:G6439-MONOMER.
ECOL316407:JW5112-MONOMER.
MetaCyc:G6439-MONOMER.

Miscellaneous databases

PROiP75806.

Family and domain databases

CDDicd03385. PAP2_BcrC_like. 1 hit.
Gene3Di1.20.144.10. 1 hit.
InterProiIPR000326. P_Acid_Pase_2/haloperoxidase.
IPR033879. UPP_Pase.
[Graphical view]
PfamiPF01569. PAP2. 1 hit.
[Graphical view]
SMARTiSM00014. acidPPc. 1 hit.
[Graphical view]
SUPFAMiSSF48317. SSF48317. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYBJG_ECOLI
AccessioniPrimary (citable) accession number: P75806
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: November 30, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.