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P75806

- YBJG_ECOLI

UniProt

P75806 - YBJG_ECOLI

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Protein

Putative undecaprenyl-diphosphatase YbjG

Gene

ybjG

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli

Functioni

Overexpression leads to increased undecaprenyl diphosphatase activity and to increased resistance to bacitracin. May have a preferred substrate other than undecaprenyl diphosphate in vivo.1 Publication

Catalytic activityi

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate.

GO - Molecular functioni

  1. undecaprenyl-diphosphatase activity Source: EcoCyc

GO - Biological processi

  1. cell wall organization Source: UniProtKB-KW
  2. peptidoglycan biosynthetic process Source: UniProtKB-KW
  3. regulation of cell shape Source: UniProtKB-KW
  4. response to antibiotic Source: EcoCyc
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Antibiotic resistance, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciEcoCyc:G6439-MONOMER.
ECOL316407:JW5112-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative undecaprenyl-diphosphatase YbjG (EC:3.6.1.27)
Alternative name(s):
Undecaprenyl pyrophosphate phosphatase
Gene namesi
Name:ybjG
Ordered Locus Names:b0841, JW5112
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG13676. ybjG.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 198198Putative undecaprenyl-diphosphatase YbjGPRO_0000168739Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP75806.

Interactioni

Protein-protein interaction databases

STRINGi511145.b0841.

Structurei

3D structure databases

ProteinModelPortaliP75806.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2727CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini49 – 579PeriplasmicSequence Analysis
Topological domaini79 – 12042CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini144 – 1496PeriplasmicSequence Analysis
Topological domaini173 – 19826CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei28 – 4821HelicalSequence AnalysisAdd
BLAST
Transmembranei58 – 7821HelicalSequence AnalysisAdd
BLAST
Transmembranei121 – 14323HelicalSequence AnalysisAdd
BLAST
Transmembranei150 – 17223HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the BcrC/YbjG family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0671.
HOGENOMiHOG000221066.
InParanoidiP75806.
KOiK06153.
OMAiWHRVWSG.
OrthoDBiEOG661HBQ.
PhylomeDBiP75806.

Family and domain databases

Gene3Di1.20.144.10. 1 hit.
InterProiIPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view]
PfamiPF01569. PAP2. 1 hit.
[Graphical view]
SMARTiSM00014. acidPPc. 1 hit.
[Graphical view]
SUPFAMiSSF48317. SSF48317. 1 hit.

Sequencei

Sequence statusi: Complete.

P75806-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLENLNLSLF SLINATPDSA PWMISLAIFI AKDLITVVPL LAVVLWLWGL
60 70 80 90 100
TAQRQLVIKI AIALAVSLFV SWTMGHLFPH DRPFVENIGY NFLHHAADDS
110 120 130 140 150
FPSDHGTVIF TFALAFLCWH RLWSGSLLMV LAVVIAWSRV YLGVHWPLDM
160 170 180 190
LGGLLAGMIG CLSAQIIWQA MGHKLYQRLQ SWYRVCFALP IRKGWVRD
Length:198
Mass (Da):22,399
Last modified:February 1, 1997 - v1
Checksum:iA1ED7A934F78A15D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00096 Genomic DNA. Translation: AAC73928.1.
AP009048 Genomic DNA. Translation: BAA35544.1.
PIRiA64822.
RefSeqiNP_415362.1. NC_000913.3.
YP_489114.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC73928; AAC73928; b0841.
BAA35544; BAA35544; BAA35544.
GeneIDi12933833.
945450.
KEGGiecj:Y75_p0814.
eco:b0841.
PATRICi32116885. VBIEscCol129921_0868.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00096 Genomic DNA. Translation: AAC73928.1 .
AP009048 Genomic DNA. Translation: BAA35544.1 .
PIRi A64822.
RefSeqi NP_415362.1. NC_000913.3.
YP_489114.1. NC_007779.1.

3D structure databases

ProteinModelPortali P75806.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 511145.b0841.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC73928 ; AAC73928 ; b0841 .
BAA35544 ; BAA35544 ; BAA35544 .
GeneIDi 12933833.
945450.
KEGGi ecj:Y75_p0814.
eco:b0841.
PATRICi 32116885. VBIEscCol129921_0868.

Organism-specific databases

EchoBASEi EB3440.
EcoGenei EG13676. ybjG.

Phylogenomic databases

eggNOGi COG0671.
HOGENOMi HOG000221066.
InParanoidi P75806.
KOi K06153.
OMAi WHRVWSG.
OrthoDBi EOG661HBQ.
PhylomeDBi P75806.

Enzyme and pathway databases

BioCyci EcoCyc:G6439-MONOMER.
ECOL316407:JW5112-MONOMER.

Miscellaneous databases

PROi P75806.

Gene expression databases

Genevestigatori P75806.

Family and domain databases

Gene3Di 1.20.144.10. 1 hit.
InterProi IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view ]
Pfami PF01569. PAP2. 1 hit.
[Graphical view ]
SMARTi SM00014. acidPPc. 1 hit.
[Graphical view ]
SUPFAMi SSF48317. SSF48317. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Identification of multiple genes encoding membrane proteins with undecaprenyl pyrophosphate phosphatase (UppP) activity in Escherichia coli."
    El Ghachi M., Derbise A., Bouhss A., Mengin-Lecreulx D.
    J. Biol. Chem. 280:18689-18695(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  5. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYBJG_ECOLI
AccessioniPrimary (citable) accession number: P75806
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: October 29, 2014
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3