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Protein

Glutathione transport system permease protein GsiD

Gene

gsiD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Part of the ABC transporter complex GsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane (Probable).1 Publication

GO - Biological processi

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:YLID-MONOMER
MetaCyc:YLID-MONOMER

Protein family/group databases

TCDBi3.A.1.5.11 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione transport system permease protein GsiD
Gene namesi
Name:gsiD
Synonyms:yliD
Ordered Locus Names:b0832, JW0816
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13475 gsiD

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei40 – 60HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei105 – 125HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei144 – 164HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei165 – 185HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei222 – 242HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei266 – 286HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000602621 – 303Glutathione transport system permease protein GsiDAdd BLAST303

Proteomic databases

PaxDbiP75799
PRIDEiP75799

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (GsiA), two transmembrane proteins (GsiC and GsiD) and a solute-binding protein (GsiB).Curated

Protein-protein interaction databases

BioGridi425998435 interactors.
STRINGi316385.ECDH10B_0901

Structurei

3D structure databases

ProteinModelPortaliP75799
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini101 – 290ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST190

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C2T Bacteria
COG1173 LUCA
HOGENOMiHOG000171368
InParanoidiP75799
KOiK13891
OMAiTEFWRKF
PhylomeDBiP75799

Family and domain databases

CDDicd06261 TM_PBP2, 1 hit
Gene3Di1.10.3720.101 hit
InterProiView protein in InterPro
IPR000515 MetI-like
IPR035906 MetI-like_sf
IPR025966 OppC_N
PfamiView protein in Pfam
PF00528 BPD_transp_1, 1 hit
PF12911 OppC_N, 1 hit
SUPFAMiSSF161098 SSF161098, 1 hit
PROSITEiView protein in PROSITE
PS50928 ABC_TM1, 1 hit

Sequencei

Sequence statusi: Complete.

P75799-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLFNWRRQA VLNAMPLVKP DQVRTPWHEF WRRFRRQHMA MTAALFVILL
60 70 80 90 100
IVVAIFARWI APYDAENYFD YDNLNNGPSL QHWFGVDSLG RDIFSRVLVG
110 120 130 140 150
AQISLAAGVF AVFIGAAIGT LLGLLAGYYE GWWDRLIMRI CDVLFAFPGI
160 170 180 190 200
LLAIAVVAVL GSGIANVIIA VAIFSIPAFA RLVRGNTLVL KQQTFIESAR
210 220 230 240 250
SIGASDMTVL LRHILPGTVS SIVVFFTMRI GTSIISAASL SFLGLGAQPP
260 270 280 290 300
TPEWGAMLNE ARADMVIAPH VAVFPALAIF LTVLAFNLLG DGLRDALDPK

IKG
Length:303
Mass (Da):33,238
Last modified:February 1, 1997 - v1
Checksum:i94586DD1037F9D5E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC73919.1
AP009048 Genomic DNA Translation: BAA35527.1
PIRiH64820
RefSeqiNP_415353.1, NC_000913.3
WP_001236051.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73919; AAC73919; b0832
BAA35527; BAA35527; BAA35527
GeneIDi945461
KEGGiecj:JW0816
eco:b0832
PATRICifig|1411691.4.peg.1446

Similar proteinsi

Entry informationi

Entry nameiGSID_ECOLI
AccessioniPrimary (citable) accession number: P75799
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome