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Protein

Glutathione transport system permease protein GsiD

Gene

gsiD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of the ABC transporter complex GsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane (Probable).1 Publication

GO - Molecular functioni

  • glutathione transmembrane transporter activity Source: EcoCyc

GO - Biological processi

  • glutathione transmembrane transport Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YLID-MONOMER.
ECOL316407:JW0816-MONOMER.
MetaCyc:YLID-MONOMER.

Protein family/group databases

TCDBi3.A.1.5.11. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione transport system permease protein GsiD
Gene namesi
Name:gsiD
Synonyms:yliD
Ordered Locus Names:b0832, JW0816
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13475. gsiD.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei40 – 6021HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei105 – 12521HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei144 – 16421HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei165 – 18521HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei222 – 24221HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei266 – 28621HelicalPROSITE-ProRule annotationAdd
BLAST

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 303303Glutathione transport system permease protein GsiDPRO_0000060262Add
BLAST

Proteomic databases

PaxDbiP75799.

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (GsiA), two transmembrane proteins (GsiC and GsiD) and a solute-binding protein (GsiB).Curated

Protein-protein interaction databases

BioGridi4259984. 14 interactions.
STRINGi511145.b0832.

Structurei

3D structure databases

ProteinModelPortaliP75799.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini101 – 290190ABC transmembrane type-1PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C2T. Bacteria.
COG1173. LUCA.
HOGENOMiHOG000171368.
InParanoidiP75799.
KOiK13891.
OMAiFTLMIQA.
PhylomeDBiP75799.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
IPR025966. OppC_N.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
PF12911. OppC_N. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P75799-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLFNWRRQA VLNAMPLVKP DQVRTPWHEF WRRFRRQHMA MTAALFVILL
60 70 80 90 100
IVVAIFARWI APYDAENYFD YDNLNNGPSL QHWFGVDSLG RDIFSRVLVG
110 120 130 140 150
AQISLAAGVF AVFIGAAIGT LLGLLAGYYE GWWDRLIMRI CDVLFAFPGI
160 170 180 190 200
LLAIAVVAVL GSGIANVIIA VAIFSIPAFA RLVRGNTLVL KQQTFIESAR
210 220 230 240 250
SIGASDMTVL LRHILPGTVS SIVVFFTMRI GTSIISAASL SFLGLGAQPP
260 270 280 290 300
TPEWGAMLNE ARADMVIAPH VAVFPALAIF LTVLAFNLLG DGLRDALDPK

IKG
Length:303
Mass (Da):33,238
Last modified:February 1, 1997 - v1
Checksum:i94586DD1037F9D5E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73919.1.
AP009048 Genomic DNA. Translation: BAA35527.1.
PIRiH64820.
RefSeqiNP_415353.1. NC_000913.3.
WP_001236051.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73919; AAC73919; b0832.
BAA35527; BAA35527; BAA35527.
GeneIDi945461.
KEGGiecj:JW0816.
eco:b0832.
PATRICi32116867. VBIEscCol129921_0859.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73919.1.
AP009048 Genomic DNA. Translation: BAA35527.1.
PIRiH64820.
RefSeqiNP_415353.1. NC_000913.3.
WP_001236051.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP75799.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259984. 14 interactions.
STRINGi511145.b0832.

Protein family/group databases

TCDBi3.A.1.5.11. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP75799.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73919; AAC73919; b0832.
BAA35527; BAA35527; BAA35527.
GeneIDi945461.
KEGGiecj:JW0816.
eco:b0832.
PATRICi32116867. VBIEscCol129921_0859.

Organism-specific databases

EchoBASEiEB3248.
EcoGeneiEG13475. gsiD.

Phylogenomic databases

eggNOGiENOG4105C2T. Bacteria.
COG1173. LUCA.
HOGENOMiHOG000171368.
InParanoidiP75799.
KOiK13891.
OMAiFTLMIQA.
PhylomeDBiP75799.

Enzyme and pathway databases

BioCyciEcoCyc:YLID-MONOMER.
ECOL316407:JW0816-MONOMER.
MetaCyc:YLID-MONOMER.

Miscellaneous databases

PROiP75799.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
IPR025966. OppC_N.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
PF12911. OppC_N. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGSID_ECOLI
AccessioniPrimary (citable) accession number: P75799
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: September 7, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.