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P75793

- PFLF_ECOLI

UniProt

P75793 - PFLF_ECOLI

Protein

Putative formate acetyltransferase 3

Gene

ybiW

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 101 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Acetyl-CoA + formate = CoA + pyruvate.

    Pathwayi

    GO - Molecular functioni

    1. formate C-acetyltransferase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciEcoCyc:G6426-MONOMER.
    ECOL316407:JW0807-MONOMER.
    UniPathwayiUPA00920; UER00891.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative formate acetyltransferase 3 (EC:2.3.1.54)
    Alternative name(s):
    Pyruvate formate-lyase 3
    Gene namesi
    Name:ybiW
    Ordered Locus Names:b0823, JW0807
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG13328. ybiW.

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 810810Putative formate acetyltransferase 3PRO_0000166690Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei786 – 7861Glycine radicalPROSITE-ProRule annotation

    Keywords - PTMi

    Organic radical

    Proteomic databases

    PaxDbiP75793.
    PRIDEiP75793.

    Expressioni

    Gene expression databases

    GenevestigatoriP75793.

    Interactioni

    Protein-protein interaction databases

    IntActiP75793. 6 interactions.
    STRINGi511145.b0823.

    Structurei

    3D structure databases

    ProteinModelPortaliP75793.
    SMRiP75793. Positions 6-810.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini11 – 682672PFLPROSITE-ProRule annotationAdd
    BLAST
    Domaini689 – 810122Glycine radicalPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 glycine radical domain.PROSITE-ProRule annotation
    Contains 1 PFL domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG1882.
    HOGENOMiHOG000274400.
    KOiK00656.
    OMAiENCDIIA.
    OrthoDBiEOG65TRNB.
    PhylomeDBiP75793.

    Family and domain databases

    InterProiIPR019777. Form_AcTrfase_GR_CS.
    IPR001150. Gly_radical.
    IPR010098. PFL2/GDeHydtase_fam.
    IPR004184. PFL_dom.
    [Graphical view]
    PfamiPF01228. Gly_radical. 1 hit.
    PF02901. PFL. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01774. PFL2-3. 1 hit.
    PROSITEiPS00850. GLY_RADICAL_1. 1 hit.
    PS51149. GLY_RADICAL_2. 1 hit.
    PS51554. PFL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P75793-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTTLKLDTLS DRIKAHKNAL VHIVKPPVCT ERAQHYTEMY QQHLDKPIPV    50
    RRALALAHHL ANRTIWIKHD ELIIGNQASE VRAAPIFPEY TVSWIEKEID 100
    DLADRPGAGF AVSEENKRVL HEVCPWWRGQ TVQDRCYGMF TDEQKGLLAT 150
    GIIKAEGNMT SGDAHLAVNF PLLLEKGLDG LREEVAERRS RINLTVLEDL 200
    HGEQFLKAID IVLVAVSEHI ERFAALAREM AATETRESRR DELLAMAENC 250
    DLIAHQPPQT FWQALQLCYF IQLILQIESN GHSVSFGRMD QYLYPYYRRD 300
    VELNQTLDRE HAIEMLHSCW LKLLEVNKIR SGSHSKASAG SPLYQNVTIG 350
    GQNLVDGQPM DAVNPLSYAI LESCGRLRST QPNLSVRYHA GMSNDFLDAC 400
    VQVIRCGFGM PAFNNDEIVI PEFIKLGIEP QDAYDYAAIG CIETAVGGKW 450
    GYRCTGMSFI NFARVMLAAL EGGHDATSGK VFLPQEKALS AGNFNNFDEV 500
    MDAWDTQIRY YTRKSIEIEY VVDTMLEENV HDILCSALVD DCIERAKSIK 550
    QGGAKYDWVS GLQVGIANLG NSLAAVKKLV FEQGAIGQQQ LAAALADDFD 600
    GLTHEQLRQR LINGAPKYGN DDDTVDTLLA RAYQTYIDEL KQYHNPRYGR 650
    GPVGGNYYAG TSSISANVPF GAQTMATPDG RKAHTPLAEG ASPASGTDHL 700
    GPTAVIGSVG KLPTAAILGG VLLNQKLNPA TLENESDKQK LMILLRTFFE 750
    VHKGWHIQYN IVSRETLLDA KKHPDQYRDL VVRVAGYSAF FTALSPDAQD 800
    DIIARTEHML 810
    Length:810
    Mass (Da):90,125
    Last modified:February 1, 1997 - v1
    Checksum:i8578C59C67F95DE1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00096 Genomic DNA. Translation: AAC73910.1.
    AP009048 Genomic DNA. Translation: BAA35504.1.
    PIRiG64819.
    RefSeqiNP_415344.1. NC_000913.3.
    YP_489096.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC73910; AAC73910; b0823.
    BAA35504; BAA35504; BAA35504.
    GeneIDi12930984.
    945444.
    KEGGiecj:Y75_p0796.
    eco:b0823.
    PATRICi32116849. VBIEscCol129921_0850.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00096 Genomic DNA. Translation: AAC73910.1 .
    AP009048 Genomic DNA. Translation: BAA35504.1 .
    PIRi G64819.
    RefSeqi NP_415344.1. NC_000913.3.
    YP_489096.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P75793.
    SMRi P75793. Positions 6-810.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P75793. 6 interactions.
    STRINGi 511145.b0823.

    Proteomic databases

    PaxDbi P75793.
    PRIDEi P75793.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC73910 ; AAC73910 ; b0823 .
    BAA35504 ; BAA35504 ; BAA35504 .
    GeneIDi 12930984.
    945444.
    KEGGi ecj:Y75_p0796.
    eco:b0823.
    PATRICi 32116849. VBIEscCol129921_0850.

    Organism-specific databases

    EchoBASEi EB3112.
    EcoGenei EG13328. ybiW.

    Phylogenomic databases

    eggNOGi COG1882.
    HOGENOMi HOG000274400.
    KOi K00656.
    OMAi ENCDIIA.
    OrthoDBi EOG65TRNB.
    PhylomeDBi P75793.

    Enzyme and pathway databases

    UniPathwayi UPA00920 ; UER00891 .
    BioCyci EcoCyc:G6426-MONOMER.
    ECOL316407:JW0807-MONOMER.

    Miscellaneous databases

    PROi P75793.

    Gene expression databases

    Genevestigatori P75793.

    Family and domain databases

    InterProi IPR019777. Form_AcTrfase_GR_CS.
    IPR001150. Gly_radical.
    IPR010098. PFL2/GDeHydtase_fam.
    IPR004184. PFL_dom.
    [Graphical view ]
    Pfami PF01228. Gly_radical. 1 hit.
    PF02901. PFL. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01774. PFL2-3. 1 hit.
    PROSITEi PS00850. GLY_RADICAL_1. 1 hit.
    PS51149. GLY_RADICAL_2. 1 hit.
    PS51554. PFL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

    Entry informationi

    Entry nameiPFLF_ECOLI
    AccessioniPrimary (citable) accession number: P75793
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1998
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 101 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3